Immune bovine colostrum and method for preparing bifidobacteria composite tiny capsule and pill

A bifidobacterium and colostrum technology, applied in the direction of medical preparations containing active ingredients, sugar-coated pills, pill delivery, etc., can solve the problems of reducing the activity, quantity and potency of immune bovine colostrum and bifidobacteria, and achieve Good release effect in the intestinal tract, strong acid resistance and anti-digestive enzyme properties, high immunity and micro-ecological regulation dual activity effect
CN101219152BInactive Publication Date: 2010-08-04JILIN AGRICULTURAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JILIN AGRICULTURAL UNIV
Publication Date
2010-08-04
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a preparation method of a compound micro-capsule of hyper-immune bovine colostrum and bacillus bifidus which inoculates bacillus bifidus (inoculum concentration: 1-10 percent ) to degreased hyper-immune bovine colostrum that goes through ultra-high pressure sterilization and cultures for 4-24h to acquire bacillus bifidus fermented hyper-immune bovine colostrum; freeze-dryprotecting agent is added and vacuum cryodesiccation is carried out, and lyophilized powder of hyper-immune bovine colostrum and bacillus bifidus is obtained; a mother core and compound lyophilized powder with a mass ratio of 1: 4-14 are prepared into lyophilized powder of hyper-immune bovine colostrum and bacillus bifidus via air suspension granulation method, then enteric soluble opadry coatingliquid at a concentration of 5-50 percent is adopted as embedding medium for enteric coating during air suspension granulation to have the compound micro-capsule prepared. The acquired compound micro-capsule can stand the killing of gastric acid, remain immune effectively and micro-ecological double reactive, reduce the loss of activity, quantity and potency of hyper-immune bovine colostrum and bacillus bifidus during the production and usage process of the product and enhance health care function of the product to human body.
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Description

technical field

[0001] The invention relates to a method for preparing composite microcapsules with good immunity and microecological regulation dual activities through vacuum freeze-drying, suspension granulation and enteric coating after fermenting immunized bovine colostrum by using bifidobacteria. Background technique

[0002] At the end of the 19th century, humans began to recognize bifidobacteria and immune milk. After more than a century of research and practice, human beings have understood and mastered the basic characteristics of the two, and have developed a variety of products.

[0003] Bifidobacterium is the main beneficial flora in the human intestinal tract. It can inhibit the growth and reproduction of harmful flora, promote the body's metabolism, enhance the body's resistance, and regulate the micro-ecological balance in the human body. It has been used in health care drugs and food. Bifidobacterium products are very popular in countries such as Japan, Euro...

Claims

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