Method of preparing traditional Chinese medicine preparation for treating melancholia and anxiety neurosis

A technology of traditional Chinese medicine preparations and anxiety disorders, applied in the field of medicine, can solve the problems of affecting curative effect, large toxic and side effects, and difficult to cover up the bad taste of traditional Chinese medicine.

Inactive Publication Date: 2008-08-20
HOSPITAL NO 3 CPLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patients suffering from depression, anxiety and neurasthenia need long-term medication. Western medicine cannot solve the problem from the etiology, and long-term use has serious side effects
[0005] In solid preparations, the disintegration time of tablets is longer and the bioavailability is low; powders and granules are not easy to cover the bad taste of traditional Chinese medicine and are easy to absorb moisture, are not easy to store, affect the curative effect, and cannot meet the needs of the majority of patients

Method used

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  • Method of preparing traditional Chinese medicine preparation for treating melancholia and anxiety neurosis
  • Method of preparing traditional Chinese medicine preparation for treating melancholia and anxiety neurosis
  • Method of preparing traditional Chinese medicine preparation for treating melancholia and anxiety neurosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The raw materials used in this example are 150g sunburned astragalus, 100g American ginseng, 100g Atractylodes macrocephala, 100g Gastrodia elata, 100g medlar, 100g rehmannia glutinosa, 100g white peony root, 100g donkey-hide gelatin, 100g salvia miltiorrhiza, 100g angelica, 100g Chuanxiong, 100g epimedium, jujube Jen 150g, Polygala 100g, Poria cocos 100g, antler 50g.

[0068] The preparation process of this embodiment is:

[0069] (1) the raw material medicine of above-mentioned weight is washed, pulverizes, for subsequent use;

[0070] (2) Combine the 13 medicinal materials of Radix Astragalus, Atractylodes macrocephala, Gastrodia elata, medlar, rehmannia glutinosa, white peony root, salvia miltiorrhiza, angelica, chuanxiong, epimedium, jujube seed, polygala and poria cocos, add water and decoct, combine the decoction, and filter , the filtrate was concentrated under reduced pressure to an extract with a relative density of 1.13, thermally measured at 60°C, dried and...

Embodiment 2

[0075] The raw materials used in this example are 200g sunburned astragalus, 150g American ginseng, 150g Atractylodes macrocephala, 150g Gastrodia elata, 150g medlar, 150g rehmannia glutinosa, 150g white peony root, 150g donkey-hide gelatin, 150g salvia miltiorrhiza, 50g angelica, 50g Chuanxiong, 50g epimedium, jujube Jen 100g, Polygala 50g, Poria cocos 50g, antler 20g.

[0076] The preparation process of this embodiment is:

[0077] (1) the raw material medicine of above-mentioned weight is washed, pulverizes, for subsequent use;

[0078] (2) Combine the 13 medicinal materials of Radix Astragalus, Atractylodes macrocephala, Gastrodia elata, medlar, rehmannia glutinosa, white peony root, salvia miltiorrhiza, angelica, chuanxiong, epimedium, jujube seed, polygala and poria cocos, add water and decoct, combine the decoction, and filter , the filtrate was concentrated under reduced pressure to an extract with a relative density of 1.13, thermally measured at 60°C, dried and crus...

Embodiment 3

[0083] The raw materials used in this example are 100g sunburned astragalus, 50g American ginseng, 50g Atractylodes macrocephala, 50g Gastrodia elata, 50g medlar, 50g rehmannia glutinosa, 50g white peony root, 50g donkey-hide gelatin, 150g salvia miltiorrhiza, 150g angelica, 150g chuanxiong, 150g epimedium, jujube Jen 200g, Polygala 150g, Poria cocos 150g, antler 100g.

[0084] The preparation process of this embodiment is the same as that of Example 2.

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Abstract

The invention relates to a preparation method of Chinese herbal medicine preparation for treating depression and anxiety disorder, having the materials of roasted milkvetch root, Largehead Atractylodes Rhizome, Rhizoma Gastrodiae, medlar, Prepared Rehmannia Root, root of herbaceous peony, danshen root, angelica sinensis, Szechwan Lovage Rhizome, Epimedium Herb, semen zizyphi spinosae, polygalae, pachyma cocos, medicinal glue, American ginseng and Hairy Antler. The water volume of water decoction, extraction time and extraction times of the roasted milkvetch root, Largehead Atractylodes Rhizome, Rhizoma Gastrodiae, medlar, Prepared Rehmannia Root, root of herbaceous peony, danshen root, angelica sinensis, Szechwan Lovage Rhizome, Epimedium Herb, semen zizyphi spinosae, polygalae, pachyma cocos are preferred by adopting orthogonal test in the invention, which remain every component of medicinal materials having effect on the indications to the utmost extent; simultaneously the extraction of ineffective ingredient is reduced; the concentration is processed, and the active ingredient is not lost; the cost is lowered; the medicinal glue, American ginseng and Hairy Antler are ground, and the raw powder is used as medicines. The capsules prepared by the preparation method of Chinese herbal medicine preparation has the advantages of convenient administration, small administration dosage, easy discharge of the drug active ingredient, rapid absorption, increased bioavailability and fully exerted drug efficacy.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of a traditional Chinese medicine preparation for treating depression and anxiety. Background technique [0002] According to the statistics of the national health department, with the gradual acceleration of the pace of life in modern society and the increasing pressure of study, employment, work and life, more and more people suffer from neurological diseases such as insomnia, depression, anxiety and neurasthenia. Such diseases have been recognized as invisible killers that seriously threaten human health. Therefore, it is imperative to prevent and treat such diseases. [0003] Depression is an emotional mental illness with unknown causes, characterized by low emotion, slow thinking, and decreased and sluggish language movements. This disease belongs to the category of diseases such as depression syndrome and dementia in traditional Chinese me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K9/48A61K47/36A61P25/22A61P25/24A61K35/32A61K35/36
Inventor 李新田杨来启张彦林昱史锋庆
Owner HOSPITAL NO 3 CPLA
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