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Medicine composition of protracted withdrawal syndrome after heroin-addicts detoxify

A composition and heroin technology, applied in the field of medicine, can solve the problems of increased tolerance, restricted drug application, large adverse reactions and the like

Inactive Publication Date: 2010-11-17
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the abuse of benzodiazepines among drug users More patients with this type of drug lead to increased tolerance of this type of drug among heroin addicts. In addition, this type of drug is also dependent, which greatly limits the application of this type of drug
Cao Changan and others reported the curative effect of mirtazapine and diazepam on insomnia and anxiety after withdrawal of heroin addicts, and believed that these two drugs have good anti-anxiety and sleep-improving effects, but the adverse effects of these two drugs Larger response

Method used

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  • Medicine composition of protracted withdrawal syndrome after heroin-addicts detoxify
  • Medicine composition of protracted withdrawal syndrome after heroin-addicts detoxify
  • Medicine composition of protracted withdrawal syndrome after heroin-addicts detoxify

Examples

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example 1

[0062] Recipe: Ginseng 10g, Rehmannia glutinosa 20g, Chuanxiong 10g, Asarum 8g, Pinellia 12g, Notopterygium 10g and Citrus aurantium 10g.

[0063] Method: Take Rhizoma Chuanxiong, Pinellia, Notopterygium and Citrus aurantium, add 6 times the amount of 70% ethanol to reflux and extract twice, each time for two hours, combine the extracts, filter, recover ethanol, concentrate, centrifuge, spray dry to make dry powder; Ginseng, Rehmannia glutinosa, and Asarum, add 8 times the amount of water to extract twice, each time for two hours, combine the extracts, filter, concentrate, centrifuge, and spray dry to make dry powder; combine the above two dry powders, mix well, add appropriate amount of starch and Sodium carboxymethyl starch, made into granules, dried and granulated to obtain granules.

example 2

[0065] Recipe: ginseng 6g, rehmannia glutinosa 15g, chuanxiong 6g, asarum 5g, pinellia 8g, notopterygium 5g and citrus aurantium 9g.

[0066] Method: Take Rhizoma Chuanxiong, Pinellia, Notopterygium and Citrus aurantium, add 6 times the amount of 70% ethanol to reflux and extract twice, each time for two hours, combine the extracts, filter, recover ethanol, concentrate, centrifuge, spray dry to make dry powder; Ginseng, Rehmannia glutinosa, and Asarum, add 8 times the amount of water to extract twice, each time for two hours, combine the extracts, filter, concentrate, centrifuge, and spray dry to make dry powder; combine the above two dry powders, mix well, add appropriate amount of starch and Sodium carboxymethyl starch, granulated, dried, compressed into tablets to obtain tablets.

example 3

[0068] Formula: ginseng 16g, rehmannia glutinosa 30g, chuanxiong 12g, asarum 10g, pinellia 15g, notopterygium 12g and citrus aurantium 15g.

[0069] Method: Take Rhizoma Chuanxiong, Pinellia, Notopterygium and Citrus aurantium, add 6 times the amount of 70% ethanol to reflux and extract twice, each time for two hours, combine the extracts, filter, recover ethanol, concentrate, centrifuge, spray dry to make dry powder; Ginseng, Rehmannia glutinosa, and Asarum, add 8 times the amount of water to extract twice, each time for two hours, combine the extracts, filter, concentrate, centrifuge, and spray dry to make dry powder; combine the above two dry powders, mix well, add appropriate amount of starch and Sodium carboxymethyl starch, dry compressed granules, filled capsules, to obtain capsules.

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Abstract

The invention provides a drug composite which treats protracted withdrawal syndrome of heroin addicts after detoxication. The composite consists of active ingredients and auxiliary materials which are pharmaceutically accepted and is characterized in that the active ingredients are prepared from the following crude drugs according to the parts by weight: 3 to 20 parts of ginseng, 10 to 40 parts of rehmanniae, 3 to 15 parts of ligusticum wallichii, 3 to 15 parts of manchurian wild ginger, 5 to 20 parts of pinellia tuber, 3 to 15 parts of notopterygium incisium and 5 to 20 parts of fructus aurantii. The drug composite can relieve a series of clinical symptoms such as whole body muscular pain, serious insomnia, astriction and body emaciation of the heroin addicts after detoxication and is beneficial to patients to get rid of drug addiction and get a new start.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine preparation, in particular to a Chinese patent medicine made from Chinese herbal medicines. Background technique [0002] Drug use, especially heroin addiction, is a serious social and health problem that Asian countries, including China, have faced for many years. Methadone substitution detoxification therapy is currently the most effective and widely accepted treatment method, which can make addicts get rid of heroin quickly; but because methadone itself is only a substitute, patients are prone to muscle pain all over the body after stopping the drug , severe insomnia, constipation and body weight loss and a series of clinical symptoms, the so-called protracted withdrawal syndrome. Therefore, if the above-mentioned symptoms can be relieved by drugs or other methods, it will definitely help patients to get rid of drug addiction completely and gain a new life. [0003] In pre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61P25/36
Inventor 赵学军熊天琴
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE