Disposal reagent kit and automatic chemosynthesis main machine

Abstract

The invention provides a disposable kit and an automatic chemical synthesis main machine. The disposable kit and the automatic chemical synthesis main machine are used for synthesizing a short-life radio-labeling medicine for disease diagnosis. The invention comprises two parts of the main machine and the kit. The kit is characterized in that a pipe communicated with a reagent or container is provided with a valve piece set which can be conveniently connected and disconnected with a valve piece of the chemical automatic synthesis main machine; the kit comprises a gas channel sealing interface which can be conveniently connected and disconnected with a gas channel sealing interface of the main machine; a container for holding the reagent and the container or pipe needing to be sealed in storage and transportation are provided with sealing devices which can be quickly opened; and the spatial position and the communication relation of the structure correspond to the particular synthetic reaction and the corresponding main machine structure. The main machine has corresponding characteristics. Under conditions of larger cost-performance ratio, the invention reduces the complex manual operation procedures before and after the synthesis and facilitates the in-site synthesis of the short-life chemicals.

Description

technical field [0001] The invention relates to a chemical synthesis device, especially an automatic chemical synthesis device. Background technique [0002] Automated chemical synthesis devices are now widely used for radiolabeled drugs, which are used in disease diagnosis; due to the radioactive contamination of these drugs and their short effective half-life, they need to be synthesized in hospitals before being administered to patients , not in the factory; therefore, it is mostly carried out in an automated way. [0003] The main mode of use of this type of drug is: the manufacturer provides the precursor and various raw material reagents for the synthesis of this type of drug to the hospital, and at the same time provides the synthesis equipment that can be automatically controlled, and the hospital staff will synthesize the drug according to the requirements and then give it to the patient. Although the reaction process, such as heating, cooling, and transfer of reac...

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Problems solved by technology

[0005] As compared with other patents cited in the above patents: US7559531 cannot be made into a disposable device; WO9311871 contains a syringe driven by a stepping motor to contain reagents, which is complicated and expensive and requires manual operation; US5415843 contains a disposable kit, but the kit does not contain pipelines ; US5312592 contains a disposable kit with tubing but also uses a syringe

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