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Soluble powder for preventing and treating colibacillosis of fowl

A poultry colibacillosis, soluble technology, applied in the direction of powder delivery, antibacterial drugs, organic active ingredients, etc., can solve the problems of unsatisfactory therapeutic effect and drug residue, and achieve drug resistance, high safety, and oral absorption good effect

Inactive Publication Date: 2009-07-01
TIANJIN RINGPU BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the current bacterial diseases of livestock and poultry are mostly mixed infection or secondary infection of multiple bacteria, single use of one antibiotic treatment can no longer achieve the desired therapeutic effect, and it is also easy to change many bacteria from single drug resistance to multi drug resistance , It also caused a large amount of drug residues in meat products

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: earlier sulfachlordazine sodium 90g, trimethoprim 10g and used adjuvant anhydrous glucose 900g are pulverized, cross 60 mesh sieves after pulverizing; Get sulfachlordazine sodium, trimethoprim and equivalent The excipients are diluted and mixed by the equal amount incremental dilution method, and passed through a 60-mesh fine sieve three times to obtain the mixture; the mixture is mixed with the remaining auxiliary materials evenly, and the mixture is passed through an 80-mesh fine sieve three times to obtain about 1000 g of soluble powder, which contains Sulfachlordazine sodium 90g, trimethoprim 10g.

[0015] Sulfonamides. It is mainly used for the prevention and treatment of poultry colibacillosis. Dosage: 24 mg per 1 kg of body weight per day, 3-6 consecutive days as a course of treatment.

Embodiment 2

[0016] Embodiment 2: earlier sulfachlordazine sodium 100g, trimethoprim 20g and used adjuvant anhydrous glucose 880g are pulverized, cross 60 mesh sieves after pulverizing; Get sulfachlordazine sodium, trimethoprim and equivalent The excipients are diluted and mixed by the equal amount incremental dilution method, and passed through a 60-mesh fine sieve three times to obtain the mixture; the mixture is mixed with the remaining auxiliary materials evenly, and the mixture is passed through an 80-mesh fine sieve three times to obtain about 1000 g of soluble powder, which contains Sulfachlordazine sodium 100g, trimethoprim 20g.

[0017] Sulfonamides. It is mainly used for the prevention and treatment of poultry colibacillosis. Dosage: 20 mg per 1 kg of body weight per day, 3-6 consecutive days as a course of treatment.

Embodiment 3

[0018] Embodiment 3: earlier sulfachlordazine sodium 110g, trimethoprim 30g and used adjuvant anhydrous glucose 860g are pulverized, cross 60 mesh sieves after pulverizing; Get sulfachlordazine sodium, trimethoprim and equivalent The excipients are diluted and mixed by the equal amount incremental dilution method, and passed through a 60-mesh fine sieve three times to obtain the mixture; the mixture is mixed with the remaining auxiliary materials evenly, and the mixture is passed through an 80-mesh fine sieve three times to obtain about 1000 g of soluble powder, which contains Sulfachlordazine sodium 110g, trimethoprim 30g.

[0019] Sulfonamides. It is mainly used for the prevention and treatment of poultry colibacillosis. Dosage: 14 mg per 1 kg of body weight per day, 3-6 consecutive days as a course of treatment.

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PUM

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Abstract

The invention relates to soluble powder for preventing and treating colibacillosis of poultry, comprising sulfachlorpyridazine sodium, trimethoprim and auxiliary materials. The inventive medicament is mainly used to prevent and treat colibacillosis of poultry. The sulfachlorpyridazine sodium and trimethoprim have compatibility when used together. The trimethoprim is used as an antisepsis synergist of sulfonamides when resisting bacteria, thus strengthening medicament effect of sulfachlorpyridazine sodium. The sulfachlorpyridazine sodium and trimethoprim cooperate to effectively treat colibacillosis. The soluble powder has good absorption and relatively high safety when orally taken.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, in particular to a soluble powder for preventing and treating avian colibacillosis. Background technique [0002] With the continuous development of the modern breeding industry, the ways of livestock and poultry infection are becoming more and more complicated. Various infectious diseases caused by sensitive bacteria are the most common. The main therapeutic drugs currently used to treat such diseases are antibiotics. ubiquitous. Since the current bacterial diseases of livestock and poultry are mostly mixed infections or secondary infections of multiple bacteria, the single use of one antibiotic treatment can no longer achieve the desired therapeutic effect, and it is also easy to change many bacteria from single-drug resistance to multi-drug resistance. , Meat food also caused a large amount of drug residues. Contents of the invention [0003] Based on the above situation, the object of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/635A61K9/14A61K47/26A61P31/04A61K31/505
Inventor 李旭东鲍恩东苏建东
Owner TIANJIN RINGPU BIO TECH
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