163results about How to "Reduce hyperplasia" patented technology

The invention discloses a maca, ginseng and medlar composition and an application thereof. The composition is prepared by mixing the following components in percentage by weight: 30-85% of maca, 10-40% of ginseng and 5-30% of medlar. The composition is added with edible accessory and prepared into tablets, hard capsules, granules, soft capsule, medicinal liquor, oral liquid and beverage. According to the composition disclosed by the invention, the maca, ginseng and medlar are matched and combined according to the functional characteristics thereof; the ginseng has the effects of nourishing and strengthening and tonifying middle and replenishing qi, the maca has the effects of improving sexual function, reducing benign prostatic hyperplasia and improving the fertility, and the medlar has the effects of preventing consumptive disease, essence deficiency, impotence, spermatorrhea and the like; and the three complement one another and realize a synergistic effect in improving the sexual function, reducing benign prostatic hyperplasia and improving the fertility.

The invention discloses a pyridines compound for treating liver diseases. The compound is a compound as shown in a formula I, pharmacologically acceptable salt, a hydrate, a solvate or a metabolite ofthe compound. The compound can be used for preparing a medicine for treating and/or preventing the liver diseases.

The invention relates to a porous bacterial cellulose skin repair material with a density structure and a preparation method thereof. The porous bacterial cellulose skin repair material with the 'upper dense and lower loose' structure similar to human skin is prepared by controlling the culture condition of bacterial cellulose and adding sustained-release microspheres in the culture process. A loose layer is tightly combined with a dense layer, so that obvious physical layering is avoided, and the structural continuity is good; and gradient changes of the structures are produced in the loose layer and the dense layer, and multiple pores distributed uniformly are formed in the loose layer, so that the upper dense and lower loose gradient structure of the human skin is simulated to the utmost degree. Cells easily enter the material, the healing period of a wound is obviously shortened, and proliferation of healed scars is effectively reduced; and good air permeability and water holding property of the bacterial cellulose are kept, the wound surface can be kept in a wet environment, and healing of the wound surface is facilitated. The forming process is simple, the culture period is short, the preparation process is environment-friendly, simple, convenient and quick, and the preparation cost is low.

The invention provides a biodegradable cardia support. The biodegradable cardia support comprises a biodegradable support framework which is formed by weave of biodegradable high polymer material filaments, and a layer of controlled-release drug layer is coated on the surface of the biodegradable support framework. The support framework and drug carriers are made of high polymer biodegradable materials and can fully and automatically degradate after time window treatment is finished, and therefore the trouble of taking out the support is avoided. In addition, the controlled-release drug layer can release anti-inflammatory drugs stably through drug controlled-release technology, and therefore fibroblast hyperplasia caused by esophagus repair reaction can be effectively restrained, subsequent scar tissue hyperplasia and thickening can be reduced, and tissue hyperplasia on the surface of the support after the support is implanted is restrained. Thus, the time window of support implantation treatment can be prolonged, supporting force of the support on tube walls can be increased, and long-dated reappearance can be reduced.

The invention discloses a traditional Chinese medicine composition, in particular discloses a traditional Chinese medicine composition for treating prostatic hypertrophy and a preparation method thereof. The traditional Chinese medicine composition for treating prostatic hypertrophy is characterized by being prepared from the following components: Radix scutellariae, phellodendron bark, oldenlandia, tuckahoe, rhizoma alismatis, rhizoma anemarrhenae, safflower, raspberry, self-heal, houttuynia, rough gentian, dried rehmannia root, yam rhizome, chuanxiong rhizome, angelica, morinda root, broomrape, moutan bark, gardenia, red peony root, dandelion, lysimachia, coix seed, prepared aconite root, radix linderae, cassia, rhubarb, bitter cardamon, turtle shell, centipede, bombyx batryticatus, oyster, pangolin, antler, mastic, myrrh and menthol. The traditional Chinese medicine composition prepared by the invention can be used for clearing away heat to purge pathogenic fire, removing dampness to reduce phlegm, promoting blood circulation to diminish inflammation, nourishing the kidney to replenish essence, nourishing the kidney to reduce urination, softening hardness to dissipate stagnation and dissipating blood stasis to remove stagnation, and can improve the immunity of human bodies, improve the arterial blood flow and dilate vessel walls. By using the traditional Chinese medicine composition for treating 920 cases, the total effective rate reaches 96%.

The present invention relates to a blood vessel medicine scaffold, including blood vessel scaffold, medicine and carrier, in which the medicine is coated on the surface of said blood vessel scaffold by means of carrier. The described medicine is rolimus medicine or mixture of rolimus medicine and taxol and/or hirudin, and said rolimus medicine is one of sirolimus, tacrolimus and eotarolimus or mixture of more than two kinds of them.

The invention relates to a drying processing method for traditional Chinese medicines. The drying processing method comprises the following steps: S1, cleaning fresh traditional Chinese medicines, spreading, and drying in the air till surfaces have no water droplet; S2, spreading the dried traditional Chinese medicines, and sterilizing and disinfecting with ultraviolet lamps; S3, performing microwave drying on the sterilized and disinfected traditional Chinese medicines; S4, drying products obtained in the step 3 with hot air, thereby obtaining traditional Chinese medicines after drying processing. By adopting the drying processing method for the traditional Chinese medicines, the preservation quality of the traditional Chinese medicines can be improved, the expiration date can be delayed, generation of microorganisms can be reduced, damage of effective components is avoided, and scientific and effective methods are provided for preservation of the traditional Chinese medicines.

The invention discloses a traditional Chinese medicine composition with a hangover-alleviating health care effect and a preparation method and application of the traditional Chinese medicine composition. The active ingredients of the traditional Chinese medicine composition are prepared from the following raw materials in parts by weight: 5-15 parts of hovenia dulcis thunb, 5-15 parts of the root of kudzu vine, 0.5-7.5 parts of flower of kudzu vine, 0.5-7.5 parts of dried orange peel, 1-10 parts of medicated leaven, 1-10 parts of malt, 1-10 parts of parched hawthorn fruit, 5-15 parts of xylosma root, 0.4-7 parts of fructus amomi, 0.8-9 parts of semen raphanin and 1-10 parts of poria cocos. The traditional Chinese medicine composition is prepared from pure Chinese herbs which are combined according to the traditional Chinese medicine theory of assistant and guide, and has the effects of dispelling the effect of alcohol, quenching thirst and relieving restlessness, strengthening spleen and harmonizing stomach, soothing liver and promoting the circulation of qi, clearing damp and promoting diuresis, and calming heart. Verified by experiments, the traditional Chinese medicine composition with the hangover-alleviating health care effect is capable of effectively prolonging the drunkenness incubation, shortening the lethargy time after drunkenness and improving the activity of the ethanol dehydrogenase and the acetaldehyde dehydrogenase.

Methods for treating subjects suffering from chronic kidney disease-mineral and bone disorder or other disorders resulting in primary or secondary hyperparathyroidism are described. The methods are effective in reducing serum parathyroid hormone (PTH) levels and calcium levels in patients who undergo hemodialysis. The methods described herein are also effective in slowing the progression of kidney disease and preserving kidney function. Compositions used in the described methods are also provided and comprise calcimimetics which function as agonists of the calcium sensing receptor (CaSR).

The invention provides a medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The invention also provides a method of treating a narrowing in a body passageway comprising placing an implantable medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The medicaments can be incorporated within or coated on the device. The invention further provides hydrophobic analogs of medicaments known to inhibit cell proliferation and migration.

The invention discloses an application of gastrodin to preparing medicaments for preventing and treating Alzheimer's disease. Alzheimer's disease (AD) is a neurodegenerative disease, and pathological characteristics comprise neuro fibrillary tangles formed in cells, hyperplasia of reactive microglia and glial cell, and the like, wherein the extracellular deposition of amyloid A beta is the main pathogenetic reason of AD. An AD small mouse taking a gastrodin-containing fodder is substantially improved in spatial-memory learning ability, substantially reduced in A beta level in brain and serum, and substantially reduced in amyloid plaques and microglia in brain tissue, and thus it is indicated that gastrodin is capable of preventing A beta deposition and decreasing active components causing AD mouse brain gastrodin.

The invention relates to a regeneration material of artificial dermis substitution and a preparation method thereof. In the regeneration material of a dermis substitution for tissue engineering skin for loading rhGM-CSF, the regeneration material is formed by a heparinizing collagen-chitosan bracket loading the rhGM-CSF solution. The invention further discloses a preparation method of the regeneration material. The invention provides an artificial dermis substitution with good performance for curing the whole skin coloboma of trauma, burning, chronic skin ulcer, thereby being capable of remarkably quickening the vascularization process of the regeneration material of artificial dermis substitution, decreasing the infection risk, promoting the healing of the surface of a wound and reducing the hyperplasia of scar, and thus easing the pain of patients. The invention can be widely applied for the aspects of trauma, burning, surgery reshaping, and the like. The preparing method is simple, the source of the material is wide, the production efficiency is high, and the invention is suitable for industrial production.

The invention discloses a production process of a broad-bean sauce, and belongs to the technical field of food. The broad-bean sauce comprises the following raw materials in parts by weight: broad bean 10kg, flour 2 kg, Toona tree bark 1.6 kg, Perilla leaf 620 g, cinnamon 620 g, fennel 300 g, red chili sauce 6 kg, fry salt 5 kg, ginger 550 g, garlic flake 1 kg, chili powder 50 g, pepper powder 25 g and tomato pulp 1.5 kg. The above raw materials are subjected to certain steps to obtain the thick broad-bean sauce. The broad-bean sauce has the efficacies of promoting appetite, slowing atherosclerosis, lowering cholesterol, promoting intestinal peristalsis, nourishing Qi and strengthening spleen, disinhibiting dampness and diminishing swelling. Moreover, the broad-bean sauce contains phospholipid which is the important component of brain and nerve tissues and also contains rich choline, so that the broad-bean sauce can boost brain power and enhance memory ability. The broad-bean sauce is also as a good dietetic therapy food capable of lowering the incidence rate of benign prostatic hypoplasia and intestinal cancer.

The invention provides Maca compositions, and a compound preparation and an application thereof. The invention provides the Maca zinc composition with a Maca powder and nutrition zinc as active ingredients. The invention provides the Maca-Liuweidihuang pill composition with a Maca powder and a Liuweidihuang pill extract as active ingredients. The invention provides the Maca-wolfberry-radix astragali composition with a Maca powder, radix astragali, wolfberry and soybean isoflavone as active ingredients. The invention provides the Maca-radix puerariae composition with a Maca powder, radix puerariae and raspberry as active ingredients. The series of compositions added with edible auxiliary materials can be made into tablets (pressed cadies) and capsules. The compositions are in matched combination according to respective functional characteristics, and have a series of functions of tonifying kidney, tonifying yang, relieving physical fatigue, treating prostatitis, treating climacteric syndromes and resisting depression.

An agricultural moistener system includes a sensor and a controller. The sensor is configured to provide a feedback signal based at least in part on a sensed moisture about a harvester, a sensed accretion of an agricultural product within the harvester, or any combination thereof. The controller is configured to receive the feedback signal and to control application of a solution to one or more spindles based at least in part on the feedback signal. The solution is configured to reduce a first accretion of the agricultural product about the one or more spindles, a second accretion of the agricultural product in an outlet of the harvester, or any combination thereof. The one or more spindles is configured to harvest the agricultural product from a field, and the outlet is configured to receive the agricultural product from the one or more spindles.

The invention relates to a medical composite nanofiber dressing and a preparation method thereof. The dressing is divided into an inner layer and an outer layer, the inner layer contains polyvinyl alcohol, collagen and quaternized chitosan, the outer layer contains polycaprolactone and dodecyl substituted quaternized silicone, the polyvinyl alcohol, collagen and quaternized chitosan are mixed, aninner layer PCQC5 is prepared through an electrostatic spinning method, the polycaprolactone and dodecyl-substituted quaternized silicone QP12 are used as raw materials, and an outer layer is preparedthrough an electrostatic spinning method on the basis of the inner layer PCQC5. The dressing can be used for tissue repair or scar repair, and has wide application in the field of antibacterial materials or medical instruments.

The invention discloses a plant glucomannan silicone dressing. The plant glucomannan silicone dressing is prepared from the following components in percentage by weight: 0.05-5 percent of plant glucomannan, 0.5-50 percent of silicone, 0.1-5 percent of organosilicon antibacterial agent and the balance of matrix. A preparation method of the plant glucomannan silicone dressing comprises the following steps: mixing the plant glucomannan, the silicone and the organosilicon antibacterial agent and dissolving in the matrix; sterilizing and disinfecting through irradiation to prepare a finished product. By using the plant glucomannan silicone dressing, scars can be obviously reduced or prevented from hyperplasia and softening, the color tends to be consistent with the color of surrounding skin, the symptoms of itching and pain are obviously relieved, and the congestion condition is obviously improved, so that the plant glucomannan silicone dressing can be used for inhibiting formation of early skin scars and reducing the mid-term scar hyperplasia and hardness and pigmentation of later scars, and the feelings of itching and pain of scar tissues can be effectively relieved.

The invention relates to an alternately released double slow release coating multi-functional small-bore artificial blood vessel which comprises an artificial blood vessel, wherein double-layered coatings are sprayed to the inner and outer surfaces of the artificial blood vessel, the inner coating of the double-layered coating is a PTX slow release PDMS coating PTX-PDMS and the outer coating thereof is a biodegraded VEGF gene encapsulated polylactic-hydroxyacetic acid copolymer nano microparticle slow release coating PLGA-NPs. Purposes that VEGF gene transfection expression promotes rapid endothelialization of the inner wall of the blood vessel in an early implanting stage and PTX is continuously released to inhibit follow-up intimal hyperplasia in the later stage are achieved by means of a small-bore PET blood vessel formed by the inner PTX-PDMS coating and the outer VEGF gene encapsulated PLGA-NPs slow release coating, and the multi-functional artificial blood vessel plays a synergistic role between promoting migration, proliferation and maturity of endothelial cells and inhibiting vascular smooth muscle cells of a transmembrane, so that good endothelialization of inner wall of the blood vessel and long-term smoothness after implanting are guaranteed, and the long-term smoothness of the small-bore artificial blood vessel can be obviously improved.

Provided herein are methods of treating cancers characterized by a high frequency of one or more suppressive immune cells, comprising administering a therapeutically effective amount of an enhancer ofzeste homolog 2 (EZH2) inhibitor. Also provided are combination therapies using an EZH2 inhibitor and a second agent that is an immunomodulator.

The invention discloses a method for preparing a skin regeneration material loaded with bioactive glass particles. The method specifically comprises the steps of 1, preparing glass powder; 2, preparing silk fibroin concentrated aqueous solution; and 3, mixing and evenly stirring the glass powder, polyvinyl alcohol, chitosan solution and the silk fibroin solution, conducting vacuum defoamation to obtain blended solution, obtaining a four-dimensional porous support with the freezing-drying method, cross-linking the four-dimensional porous support with glutaraldehyde solution, and conducting freeze drying again after repeated cleaning to obtain the finished product. The skin regeneration material is a high-performance skin substitute for treatment of serious skin defects like wounds and burns as well as chronic ulcers of skin, and can remarkably promote healing of a wound surface and reduce scar hyperplasia, so as to relieve pain for patients. The skin regeneration material can be widely applied to wounds, burns, plastic surgery and other aspects. The preparing method is simple, raw materials are widely available, production efficiency is high, and the preparing method is suitable for industrialized production.