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Chinese medicinal composition for treating anypnia and preparation method thereof

A composition and technology for insomnia, applied in the direction of drug combination, medical formula, drug delivery, etc., can solve problems such as inability to treat insomnia, weak ability to relieve depression, and complicated symptoms, so as to improve anxiety, yin and yang, and harmonize , the effect of solving insomnia

Active Publication Date: 2009-08-05
北京凯晋科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Existing traditional Chinese medicine preparations still have many deficiencies in the treatment of insomnia, such as insignificant curative effect, low specificity, slow onset of action, complex indications, mostly clearing the heart and calming the nerves, weak in relieving depression, and cannot completely target Liver qi disorder, liver depression and qi stagnation, dark consumption of liver blood, liver fire disturbing the mind, and yin and yang disharmony are used to treat insomnia; thus it is difficult to meet the needs of today's clinical drug development.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1: drop pill preparation

[0025] 1. Prescription

[0026] Bupleurum 10kg Scutellaria baicalensis 5kg Suanzaoren 15kg

[0027] Cyperus 10kg Paeoniae Alba 10kg Schisandra 5kg

[0028] Two. Method

[0029] Add the above six flavors, add 6 times the amount of water, soak for 3 hours, extract the volatile oil by water distillation for 4 hours, and collect the volatile oil. The distilled aqueous solution is collected in another device; Scutellaria baicalensis is decocted three times with 8 times of water, 1.5 hours each time, and the decoction is combined. , filtered, the filtrate was combined with the above aqueous solution, concentrated to a clear paste with a relative density of 1.15 (30°C-60°C), and set aside; the rest of Bupleurum and other four flavors were extracted twice with ethanol under reflux, each time for 1.5 hours, filtered , recover ethanol and concentrate to a clear paste with a relative density of 1.13 (30°C-60°C), combine with the above-menti...

Embodiment 2

[0030] Embodiment 2: drop pill preparation

[0031] 1. Prescription

[0032] Bupleurum 15kg Scutellaria baicalensis 8kg Suanzaoren 20kg

[0033] Rhizoma Cyperi 15kg, Radix Paeoniae Alba 15kg, Schisandra 8kg.

[0034] Two. Method

[0035] Add the above six flavors, add 10 times the amount of water, soak for 2 hours, extract the volatile oil by water distillation for 5 hours, collect the volatile oil, and collect the distilled aqueous solution in another device; add 8 times the amount of water to decoct Scutellaria baicalensis three times, 1.0 hours each time, and combine the decoction , filtered, the filtrate was combined with the above aqueous solution, concentrated to a clear paste with a relative density of 1.14 (30°C-60°C), and set aside; the rest of Bupleurum and other four flavors were extracted twice with ethanol under reflux, each time for 1 hour, and filtered , recover ethanol and concentrate to a clear paste with a relative density of 1.12 (30°C-60°C), combine with...

Embodiment 3

[0036] Embodiment 3: capsule preparation

[0037] 1. Prescription

[0038] Bupleurum 25kg Scutellaria baicalensis 10kg Suanzaoren 40kg

[0039] Cyperus 20kg, Radix Paeoniae Alba 20kg, Schisandra 10kg.

[0040] Two. Method

[0041] Add the above six flavors, add 10 times the amount of water, soak for 3 hours, extract the volatile oil by water distillation for 5 hours, collect the volatile oil, and collect the distilled aqueous solution in another device; add 10 times the amount of water to decoct Scutellaria baicalensis three times, 1.5 hours each time, and combine the decoction , filtered, the filtrate was combined with the above aqueous solution, concentrated to a clear paste with a relative density of 1.10 (30°C-60°C), and set aside; the rest of Bupleurum and other four flavors were extracted twice with ethanol under reflux, each time for 1.5 hours, filtered , recovering ethanol and concentrating to a clear paste with a relative density of 1.15 (30°C-60°C), combined with th...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating insomnia, and belongs to the field of traditional Chinese medicine. The active components of the traditional Chinese medicine composition for treating the insomnia are prepared from the following raw material drugs in portion by weight: 10 to 25 portions of bupleurum, 5 to 10 portions of scutellaria, 15 to 40 portions of spina date seed, 10 to 20 portions of rhizoma cyperi, 10 to 20 portions of white paeony root, and 5 to 10 portions of schisandra. The traditional Chinese medicine composition has the following advantages that: aiming at the reality of more attack symptoms but deficient treatment medicine special for liver depression and Qi stagnation type insomnia, based on pathogenesis of main curing symptoms, the composition considers the formation mechanism of the liver depression and the Qi stagnation, and considers the pathological result. The medicine selected by the formulation accords with the traditional Chinese medicine theory, the functional main treatment and the syndrome type of the main curing diseases are definite, and the composition has the efficacies of smoothening the blood circulation and developing the liver and gall based on liver governing and regulating. Through soothing the liver and regulating the vital energy, relieving depression and allaying excitement, the composition has the functions of smoothening the Qi mechanism of the liver, keeping the mind, promoting the sleep by relieving the upset and tranquilizing the mind, and treating both the symptoms and root causes, has definite curative effect through years of clinical application, and has the advantages of quick, lasting and reliable effect and no any toxic and side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating insomnia and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] Insomnia is one of the most common sleep disorders characterized by difficulty in falling asleep and maintaining sleep, and is a subjective experience in which the quality or quantity of sleep does not meet normal needs. Recent studies have shown that insomnia will not only affect the normal life of patients, but also cause gastrointestinal ulcers, diabetes, depression, schizophrenia and other diseases. The treatment of insomnia is extremely important for improving people's quality of life and obtaining health, so the treatment of insomnia cannot be ignored. [0003] Epidemiological survey shows: A study by WHO shows that nearly 27% of people in the world suffer from insomnia. Epidemiological surveys show that 33% of people in the Un...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K9/00A61K9/14A61K9/20A61K9/48A61K47/34A61P25/20A61K47/10
Inventor 骆春秀
Owner 北京凯晋科技有限公司
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