Traditional Chinese medicine compound preparation for treating spinal cord injury and method for preparing same

Abstract

The invention discloses a traditional Chinese medicine compound preparation (Jisuikang) for treating spinal cord injury (SCI) and a method for preparing same. The compound preparation is prepared from the following components by a certain proportion: milk veteh, root of red rooted salvia, hemlock parsley, red paeonia, Chinese angelica, leech, centipede, Chinese rhubarb, rhizoma alismatis, Tuckahoe, dried immature fruit of citron orange, bark of magnolia, broomrape, herba epimedii, Chinese Polyphaga, plantain seed and bitter cardamom. The method comprises the following steps: adding water to Chinese angelica, hemlock parsley, dried immature fruit of citron orange and bark of magnolia and soaking; extracting volatile oil by adopting the vapor distillation method; adding water to the residues of the volatile oil and the other 13 components, decocting for twice and concentrating the filter liquor; carrying out the alcohol extraction with alcohol and concentrating; adding the volatile oil and evenly stirring; and adding excipients of different preparation forms and preparing into oral liquid, granules, capsules or tablets by adopting the conventional preparation method. According to pharmacologic tests and clinical application results, the compound preparation has the analgesic and anti-inflammatory effects, and the overall effect on treating SCI is better than that in the existing report of the like product; the recovery rate of the compound preparation reaches above 95%; good clinical results are achieved; furthermore, the compound preparation has the advantages of low price and convenient administration.

Description

1. Technical field:

[0001] The invention relates to the technical field of Chinese herbal medicines, in particular to a compound Chinese medicine preparation for treating spinal cord injury and a preparation method thereof. 2. Background technology

[0002] Spinal cord injury (SCI) is mostly caused by trauma to the spinal cord or cauda equina to varying degrees, resulting in motor, sensory, reflex, and sphincter dysfunction below the level of damage. According to statistics, the incidence rate of SCI worldwide is 20 / 1 million to 40 / 1 million, mainly due to falls from heights, traffic accidents and sports activities, etc., often accompanied by spinal fractures, accounting for about 14% of spinal fractures. Due to its complex pathology, Western medicine treatment is mainly surgical treatment, early restoration of spinal fracture and dislocation, stabilization of the spine, early decompression, and treatment of spinal nerve regeneration are still in the experimental stage. In ...

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