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2 results about "Cystine knot" patented technology
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A cystine knot is a protein structural motif containing three disulfide bridges (formed from pairs of cysteine residues). The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, forming a rotaxane substructure. The cystine knot motif stabilizes protein structure and is conserved in proteins across various species. There are three types of cystine knot, which differ in the topology of the disulfide bonds...
Cystine knot domain fusion protein dimer
The present application relates to a protein dimer formed from a first fusion protein and a second fusion protein, wherein the first fusion protein comprises a cystine knot domain (CK) fused to a first pharmaceutically active protein and the second fusion protein comprises a CK domain fused to a second pharmaceutically active protein, wherein the two fusion proteins are covalently linked via their CK domains. The present application further relates to the individual fusion proteins, polynucleotides encoding the fusion proteins, vectors comprising the polynucleotides, and host cells comprising the vectors.
Owner:OCTAPHARMA AG
Rhabdovirus g protein having one or more cysteine-rich regions and uses thereof
PendingCN122422338ACystine knotViral glycoprotein
Owner:WILLIARD CORP