Method and apparatus for supplying and recycling oxygen in process of high-density fermentation by aerobic microorganism
An aerobic microorganism and high-density fermentation technology, applied in the field of fermentation engineering, can solve the problems of reduced oxygen utilization rate, inability to be utilized by microorganisms, and increased cost, so as to enhance the supply of oxygen, shorten the aerobic fermentation period, and improve productivity. Effect
Inactive Publication Date: 2011-01-05
NINGBO INST OF TECH ZHEJIANG UNIV ZHEJIANG
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Problems solved by technology
Although aerobic microorganisms need a large amount of oxygen in the high-density fermentation process, if a high concentration of oxygen is supplied, most of it (80% or more) will be emptied with the tail gas of the fermentation process so that it cannot be used by microorganisms. This will reduce the utilization rate of oxygen in the fermentation process, and the cost of the fermentation process will be greatly increased due to the introduction of high-concentration oxygen, so it cannot be applied in industry.
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Abstract
The invention discloses a method and an apparatus for supplying and recycling oxygen in a process of high-density fermentation of aerobic microorganism. In the aerobic microorganism fermentation process, air is used as a gas source to prepare oxygen with the high density of 50 and 90 percent through a first oxygen generator I (1), and the oxygen with the high density of 50 and 99 percent is stored in a gas storage tank (2), and continuously aerated into an aerobic microorganism fermentation tank (3) by a regulated flow rate, and the first oxygen generator I(1) continuously uses the air as thegas source to prepare the oxygen with the high density; and the gas exhausted from an outlet of a fermentation tank (3) is led into a second oxygen generator II (4) to recycle the oxygen from the second oxygen generator II, and the gas is mixed with the oxygen with the high density prepared by the first oxygen generator I (1), and the gas is again led into the fermentation tank (3) to be circularly used in the fermentation process. The method and the apparatus can improve the production ratio of the aerobic fermentation process and reduce the production cost.
Description
Oxygen supply and recovery and reuse method and equipment in aerobic microbial high-density fermentation process technical field The invention relates to a method and equipment for oxygen supply, recovery and reuse in the high-density fermentation process of aerobic microorganisms, and belongs to the technical field of fermentation engineering. Background technique In the process of aerobic fermentation, the biological oxidation process of microorganisms requires sufficient oxygen supply. Insufficient oxygen supply will seriously affect the growth of aerobic microorganisms and the synthesis of metabolites, and microorganisms can only use oxygen dissolved in the liquid phase. In order to improve productivity, it is necessary to make "oxygen supply greater than oxygen consumption" throughout the fermentation process to eliminate the impact of insufficient oxygen supply. During the fermentation process, the oxygen consumption will increase with the growth and metabolic rate o...
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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/00C12M1/04
CPCC12M41/34C12M29/24
Inventor 尚龙安张艳辉任红姜岷张虎南
Owner NINGBO INST OF TECH ZHEJIANG UNIV ZHEJIANG
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