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Application of traditional Chinese medicine composite in preparing medicine treating paroxysmal atrial fibrillation

A technology of atrial fibrillation and composition, which is applied in the field of preparation of drugs for the treatment of paroxysmal atrial fibrillation, can solve problems such as the mechanism of atrial fibrillation that cannot be explained satisfactorily alone, and achieve the effect of reducing dizziness and improving palpitations

Active Publication Date: 2010-04-28
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most scholars believe that neither of the above two possibilities can satisfactorily explain the mechanism of atrial fibrillation alone.

Method used

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  • Application of traditional Chinese medicine composite in preparing medicine treating paroxysmal atrial fibrillation
  • Application of traditional Chinese medicine composite in preparing medicine treating paroxysmal atrial fibrillation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] In order to facilitate the application of the Chinese medicine composition, the Chinese medicine composition is prepared as a capsule

[0063] prescription:

[0064] Ginseng 89g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 224g

[0065] Fried Suanzaoren 186g, Sangjisheng 186g, Radix Paeoniae Rubra 89g, Ground Beetle 75g

[0066] Gansong 89g Coptidis 45g Southern Schisandra 67g Keel 149g

[0067] Preparation:

[0068] a. Weigh the Chinese herbal medicines according to the prescription amount, and select them;

[0069] b. Ginseng was extracted three times under reflux with 70% ethanol, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, concentrated, dried, crushed into 80-mesh fine powder, and set aside;

[0070] c. Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong add 8 times the amount of 70% ethanol to reflux extraction for 3 times, the first tim...

Embodiment 2

[0076] In order to facilitate the application of the Chinese medicine composition, the Chinese medicine composition is prepared as a tablet

[0077] prescription:

[0078] Ginseng 45g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 225g

[0079] Fried Suanzaoren 186g, Sangjisheng 186g, Chishao 89g, Gansong 45g

[0080] Ground Beetle 35g Coptidis 45g Southern Schisandra 67g Keel 149g

[0081] Preparation:

[0082] a. Weigh the Chinese herbal medicines according to the prescription amount, and select them;

[0083] b. Ginseng was extracted three times under reflux with 50% ethanol, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, concentrated, dried, crushed into 80-mesh fine powder, and set aside;

[0084] c. Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong add 8 times the amount of 50% ethanol to reflux extraction for 3 times, each time for 2 hours, comb...

Embodiment 3

[0089] In order to facilitate the application of the Chinese medicine composition, the Chinese medicine composition is prepared as granules

[0090] prescription:

[0091] Ginseng 90g Ophiopogon japonicus 135g Cornus officinalis 270g Salvia miltiorrhiza 200g

[0092] Fried Suanzaoren 150g, Sangjisheng 150g, Radix Paeoniae Rubra 100g, Ground Beetle 100g

[0093] Gansong 95g Coptidis 60g Southern Schisandra 75g Keel 150g

[0094] Preparation:

[0095] a. Weigh the Chinese herbal medicines according to the prescription amount, and select them;

[0096] b. Ginseng was extracted twice with 90% ethanol under reflux, each time for 2 hours, the extracts were combined, filtered, concentrated, dried, pulverized into 80-mesh fine powder, and set aside;

[0097] c. Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong add 8 times the amount of 80% ethanol to reflux extraction twice, each time for 2 hours, combine the extracts, filter, recover eth...

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Abstract

The invention provides an application of traditional Chinese medicine composite in preparing medicine treating paroxysmal atrial fibrillation. Clinic trials prove that the traditional Chinese medicine composite has the functions of tonifying qi and yin, promoting blood circulation, removing meridian obstruction, clearing away the heart fire and tranquillizing, can be used for treating paroxysmal atrial fibrillation, can obviously improve clinic symptoms and performs favourable treating effect.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicine for treating paroxysmal atrial fibrillation. It belongs to the technical field of Chinese herbal medicine preparations. Background technique [0002] Atrial fibrillation (abbreviated as atrial fibrillation) is the most common arrhythmia in adults. When atrial fibrillation occurs, the ventricular beat is fast and irregular, ranging from 120 to 180 beats per minute. The vast majority of atrial fibrillation occurs in patients with organic heart disease, among which rheumatic mitral valve disease, coronary heart disease and high heart disease are the most common. It can also be associated with primary cardiomyopathy, hyperthyroidism, chronic constrictive pericarditis, and heart disease of other etiologies. It can also be caused by hypothermic anesthesia, after thoracic and cardiac surgery, acute infection and cerebrovascular accident, and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/48A61K9/20A61K9/16A61K9/14A61K9/10A61P9/06A61K35/64A61K35/02
Inventor 李向军安军永王超郑立发
Owner BEIJING YILING PHARMA
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