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Gargle with drinking safety and preparation method thereof

A mouthwash and a safe technology, which is applied in the field of mouthwash with drinking safety and its preparation, can solve the problems of mouthwash residue, side effects, accidental ingestion and drinking into the body, etc., and achieve the effect of fresh and refreshing breath

Active Publication Date: 2013-03-06
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the mouthwash will remain in the mouth after rinsing, and even if it is accidentally swallowed and drunk into the body, this chemical-containing preparation will have side effects on the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Add 2.5 grams of tea polyphenols, 1 gram of magnolol, 2 grams of paeonol, 1 gram of propyl gallate, 0.5 grams of mint, and 0.01 grams of essence into 30 grams of ethanol, stir and dissolve to obtain liquid A; Add 0.5 grams of sodium, 20 grams of glycyrrhizic acid, 0.5 grams of cyclamate, 5 grams of polyvinylpyrrolidone, and 10 grams of polyoxyethylene sorbitan monooleate into 926.99 grams of water, stir and dissolve to obtain liquid B; At the same time, slowly add liquid A into liquid B and stir evenly to obtain the mouthwash.

Embodiment 2

[0054] Add 5 grams of tea polyphenols, 0.5 grams of magnolol, 1 gram of paeonol, 0.5 grams of propyl gallate, 0.3 grams of mint, and 0.05 grams of essence into 50 grams of ethanol, stir and dissolve to obtain liquid A; Add 0.2 grams of sodium, 5 grams of glycyrrhizic acid, 1 gram of cyclamate, 0.5 grams of sodium carboxymethyl cellulose, and 15 grams of sodium lauryl sulfate into 920.95 grams of water, stir and dissolve to obtain liquid B; Slowly add liquid B into liquid B and stir evenly to obtain the mouthwash.

Embodiment 3

[0056] Add 1 g of tea polyphenols, 2 g of magnolol, 1.5 g of paeonol, 2 g of propyl gallate, 0.5 g of mint, and 0.1 g of essence into 15 g of ethanol, stir and dissolve to obtain liquid A; Add 1 gram of sodium, 10 grams of glycyrrhizic acid, 0.3 grams of cyclamate, 1 gram of hydroxyethyl cellulose, and 5 grams of fatty alcohol polyoxyethylene ether (AEO9) into 960.6 grams of water, stir and dissolve to obtain liquid B; At the same time, slowly add liquid A into liquid B and stir evenly to obtain the mouthwash.

[0057] Carry out bacteriostasis test according to GB15979-2002 " Hygienic Standard Appendix C of Disposable Hygienic Articles ", take above-mentioned each embodiment mouthwash effect 2min, the average bacteriostatic rate to E. The antibacterial rate is 100%.

[0058] Carry out safety test according to " food safety evaluation program and method ", get above-mentioned each embodiment mouthwash solution and give mouse gavage, each dosage is every 20g body weight gavage ...

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PUM

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Abstract

The invention relates to gargle with the drinking safety, comprising the following components by weight percent: 0.1-0.5 percent of tea polyphenols, 0.05-0.3 percent of magnolol, 0.05-0.3 percent of paeonol, 0.01-0.1 percent of phytic acid dodecasodium salt, 0.5-3 percent of glycyrrhizic acid, 1-5 percent of ethanol, 0.05-0.5 percent of mentha haplocalyx, 0.001-0.01 percent of essence, 0.05-0.2 percent of propylgallate, 0.01-0.1 percent of sodium cyclamate, 0.05-0.5 percent of macromolecule suspending agent, 0.3-2 percent of surface active agent and the balance of water. A preparation method of the gargle comprises the following steps of: adding tea polyphenols, magnolol, paeonol, propylgallate, mentha haplocalyx and essence into the ethanol according to the content and components, stirring for dissolving to obtain solution A; adding the phytic acid dodecasodium salt, glycyrrhizic acid, sodium cyclamate, macromolecule suspending agent and surface active agent into water, stirring for dissolving to obtain solution B; slowly adding the solution A into the solution B while stirring, and evenly stirring the mixture solution to obtain the gargle. The gargle has clear appearance, is slightly sweet in the mouth feel and ensures fresh breath after use.

Description

technical field [0001] The invention relates to an oral cleaning product liquid, in particular to a mouthwash liquid with drinking safety and a preparation method thereof. Background technique [0002] With the improvement of people's quality of life, oral hygiene has become an important part of daily life. The commonly used method of oral cavity cleaning mainly contains two kinds at present, and a kind of is to brush teeth, and a kind of is to gargle. Brushing teeth is mainly limited to after getting up in the morning and before going to bed at night, while gargling is convenient and quick. There are many varieties of mouthwashes on the market, most of which are chemical preparations or a compound of chemical preparations and Chinese herbal medicines. Because the mouthwash will remain in the mouth after gargling, and even if it is accidentally swallowed and drunk into the body, this chemical-containing preparation will have side effects on the human body. Contents of th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61K8/63A61K8/58A61K8/49A61K8/35A61K8/34A61Q11/00A61K8/9789
Inventor 张万国张忠敏葛莉娟
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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