Application of antradiacomphora extract capsule for protecting liver and promoting body immune regulation function

A technology of immune regulation and extraction, which is applied in the direction of drug combination, biological testing, and resistance to vector-borne diseases, etc.

Inactive Publication Date: 2010-07-28
WEI CHENG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The existing artificial extracts of Antrodia camphorata contain different polysaccharides and triterpenoids. There is no definite experiment to prove how effective it is in protecting the liver and the immune function of the body. Disadvantages of Antrodia camphorata extract that need to be improved

Method used

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  • Application of antradiacomphora extract capsule for protecting liver and promoting body immune regulation function
  • Application of antradiacomphora extract capsule for protecting liver and promoting body immune regulation function
  • Application of antradiacomphora extract capsule for protecting liver and promoting body immune regulation function

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Embodiment Construction

[0032] Preferred embodiments of the present invention are as follows:

[0033] (1) Liver protection test

[0034] Test groups and dosage:

[0035] 1. Dosage calculation: The recommended dosage of the present invention is 4 capsules per day, 500 mg per capsule. The daily dosage for adults is 500mg×4=2000mg / day. The oral dose for rats is calculated based on the equivalent dose conversion ratio of the surface area of ​​the experimental animal to the human body. The surface area ratio of 200 grams of rats to 70 kilograms of human beings is 0.018, so the daily dose of rats is 2000mg×0.018=0.036g / 200gbody weight, that is, 180mg / kg. The doses used in this experiment were 180, 540, and 1080 mg / kg per day, which were 1, 3, and 6 times the human dose, respectively. Rats in the control group were given the same volume of 0.5% carboxymethyl cellulose (CMC). The dosage of the control drug silymarin (sigma) was 200mg / kg.

[0036] 2. Test substance preparation: before use, untie the ca...

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Abstract

The invention tests liver protection and immune regulation functions by feeding a rat and a mouse with an antradiacomphora capsule which is prepared by adopting a special process and solid-state culture, wherein a liver protection test comprises the following steps of: inducing chronic hepatitis of the rat by using carbon tetrachloride twice a week for eight weeks, and measuring GPT and GOT, water content of liver, spleen and liver, liver protein and hydroxyproline content. The antradiacomphora capsule can lighten the rat chronic hepatitis induced by the carbon tetrachloride. A specific immunity test: the test matter is fed to the BALB/c mouse and egg albumen is injected, thereby accelerating the immune cell proliferation capacity and the effect of the immune regulation function generated by an antibody with serological specificity. A non-specific immunity test comprises the following step of: doing an oral test for consecutive six weeks by means of the BALB/c mouse. The invention accelerates the abdominal cavity phagocyte activity, regulates the anti-tumor cytohormone secretion and promotes the effect of the immune regulation function generated by a serological antibody.

Description

technical field [0001] The invention relates to an application of antrodia camphorata extract capsules for protecting the liver and improving the immune regulation function of the body. Background technique [0002] The existing artificial extracts of Antrodia camphorata contain different polysaccharides and triterpenoids. There is no definite experiment to prove how effective it is in protecting the liver and the immune function of the body. The shortcomings of Antrodia camphorata extract need to be improved. Contents of the invention [0003] The main technical problem to be solved by the present invention is to overcome the above-mentioned defects existing in the prior art, and provide an antrodia camphorata extract capsule application for protecting the liver and improving the immune regulation function of the body. In the non-specific immune function test, the present invention has Promote the activity of peritoneal phagocytes, regulate the secretion of anti-tumor ce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/06G01N33/96G01N33/68G01N33/50A61P37/02
CPCY02A50/30
Inventor 王金灿
Owner WEI CHENG BIOTECH
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