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A compound traditional Chinese medicine powder inhaler for respiratory tract infections and its preparation method
Active
CN118141855B
Improve adhesion
Improve liquidity
Powder delivery
Antivirals
Powder Inhaler
Sulfated polysaccharides
This invention discloses a compound
traditional Chinese medicine
powder
inhaler
for
respiratory tract
infections and its preparation method, relating to the field of
pharmaceutical formulation
technology. The compound
traditional Chinese medicine
powder
inhaler
for
respiratory tract
infections is composed of
polysaccharide
composite gel microspheres,
forsythia
,
scutellaria
,
honeysuckle
, and
isatis
root. The
polysaccharide
composite gel microspheres are composed of seaweed sulfated
polysaccharide
,
lentinan
,
calcium
chloride
, and
curcumin
. Seaweed sulfated polysaccharide,
lentinan
,
curcumin
, and
calcium
chloride
cross-link to form a three-dimensional network spherical structure, improving the particle morphology and flowability of the micropowder. Furthermore, due to its good hygroscopic and moisturizing properties, it competitively reduces the
moisture
absorption of the micropowder, preventing aggregation and further improving flowability. In addition, the gel microspheres have excellent adhesion, adhering to the infection site after entering the
respiratory tract
, reducing expulsion losses due to
respiration
, maintaining an
effective drug concentration
at the infection site, and improving therapeutic
efficacy
.
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Owner:
AFFILIATED HOSPITAL OF ZUNYI UNIV
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Good water solubility
Improve bioavailability
reduce adhesion
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Easy to remove
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good treatment effect
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avoid it happening again
Reduced stability