Preparation method for panax ginseng polyoses extract

Abstract

The invention relates to a preparation method of ginseng polysaccharide extractive. Ginseng coarse powder is adopted, ethanol of 60 percent to 80 percent which occupies eight times to ten times of the amount of ginseng coarse powder is added to perform reflux extraction for two to three times, decoction dregs is filtered to clean out ethanol, the purified water ten times to fifteen times of the decoction dregs is added, then hydrochloric acid is added, the pH value is regulated to be one to three, boiling-out is performed for half to two hours, the decoction dregs is filtered to repeat boiling-out once, the extracted solution is combined, filtered through and decompressed and condensed, to obtain the extracted concentrated solution, hydrochloric acid is added in the extracted concentrated solution, the pH value is regulated to be one to three, hydrogen peroxide four times to six times of the amount of hydrochloric acid is added and is agitated and thermally preserved under the temperature of 85 DEG C to 95 DEG C for one to three hours, the extracted concentrated solution is cooled to the room temperature and filtered, and the concentrated solution after being decolorized is obtained; the pH value of the concentrated solution after being decolorized is regulated by utilizing NaOH to be three to five, ethanol two times to five times the concentrated solution is added, the concentrated solution is evenly agitated and is allowed to stand, precipitation is leached and cleaned for one time by utilizing ethanol with 60 percent to 80 percent containing HCl with 0.2 percent to 2.0 percent, the precipitate is dissolved through water, the alcohol precipitation washing and the acid alcohol washing are respectively repeated for once, and white ginseng polysaccharide extractive is obtained..

Description

Technical field: [0001] The invention relates to a new extraction and refining method for extracting ginseng polysaccharides from ginseng medicinal materials, and to a preparation method of ginseng polysaccharide injection, powder injection and other pharmaceutical preparations, which are used to reduce the side effects caused by radiotherapy and chemotherapy of tumors, and can be used as immune Regulatory and adjuvant medicines for tumor therapy. Background technique: [0002] Ginseng, as a valuable traditional nourishing Chinese herbal medicine, has the functions of invigorating vitality, solidifying body fluid, and calming the nerves. It has been used clinically as early as in ancient times, and the analysis of active ingredients of ginseng by modern technology proves that ginseng polysaccharide is one of the main pharmacological active ingredients in ginseng. Ginseng contains a variety of sugars (its total sugar content is 4% to 6%), including monosaccharides, oligosacc...

AI Technical Summary

Problems solved by technology

[0004] However, due to the difficulty in extracting and separating ginseng polysaccharides, the polysaccharides extracted by traditional techniques are dark in color, and the content of the main active polysaccharides (mainly containing galacturonic acid) is relatively low, and the content of impurities is high, so allergies often occur in clinical applications. And pain and other adverse reactions, therefore, the extraction process and preparation process of ginseng polysaccharides have been studied to solve the above shortcomings or defects