Medicament composition for treating gynecologic inflammation and preparation method and application thereof

A technology of gynecological inflammation and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve problems such as local circulation disorder, difficulty in antibiotics, and lack of adhesion-relieving and pain-relieving effects of antibiotics

Inactive Publication Date: 2010-08-11
SICHUAN XUHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antibiotics in Western medicine are more effective for sensitive bacterial infections in the acute phase of gynecological inflammation. However, due to tissue adhesions and local circulation disturbances, it is

Method used

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  • Medicament composition for treating gynecologic inflammation and preparation method and application thereof
  • Medicament composition for treating gynecologic inflammation and preparation method and application thereof
  • Medicament composition for treating gynecologic inflammation and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 medicine of the present invention

[0026] Cockscomb flower 833.4g Toon skin 833.4g Pomegranate skin 558.3g

[0027] Astragalus 125.0g Atractylodes macrocephala 208.3g Chinese yam 150.0g

[0028] Quangui 25.0g, squid bone 83.3g, madder 83.3g

[0029] For the above nine flavors, add water to decoct twice, add 8 times the amount of water to decoct for 2 hours for the first time, add 6 times the amount of water to decoct for 1.5 hours for the second time, combine the two decoctions, filter, and concentrate to a relative density of 1.10 -1.15 (60 ℃) clear paste, take 2 / 3 of the liquid medicine and spray dry to get dry extract powder; take appropriate amount of dextrin and dry extract powder, mix them, put them in a fluidized bed, and use the remaining 1 / 3 medicine The liquid is used as a binder to granulate, and a total of 1000 g is prepared.

Embodiment 2

[0030] Embodiment 2 Medicine preparation of the present invention

[0031] Get raw material medicine: cockscomb flower 50g, Chinese toon bark 50g, pomegranate bark 40g, astragalus 300g, Atractylodes macrocephala 400g, Chinese yam 350g, angelica 60g, cuttlefish bone 150g, madder 150g, extract medicinal material by the method for embodiment 1, add water and decoct twice, Add 4 times the amount of water to decoct for 0.5 hours for the first time, add 4 times the amount of water to decoct for 0.5 hours for the second time, combine the two decoctions, filter, concentrate to a clear paste with a relative density of 1.10-1.15 (60°C), For granulation, the prepared granules are added with an appropriate amount of stearic acid, and compressed into tablets to obtain tablets.

Embodiment 3

[0032] Embodiment 3 preparation of medicine of the present invention

[0033] Get raw materials: cockscomb flower 150g, Chinese toon bark 150g, pomegranate bark 100g, astragalus 200g, Atractylodes macrocephala 300g, yam 250g, angelica 40g, cuttlefish bone 120g, madder 120g, extract medicinal material by the method for embodiment 1, add water decoction twice, Add 12 times the amount of water to decoct for 3 hours for the first time, add 10 times the amount of water to decoct for 2.5 hours for the second time, combine the two decoctions, filter, concentrate to a clear paste with a relative density of 1.10-1.15 (60°C), The oral liquid is prepared by adding pharmaceutically acceptable auxiliary materials.

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Abstract

The invention provides a medicament composition for treating gynecologic inflammation, which is prepared by using cockscomb flower, tree-of-heaven ailanthus bark, pomegranate rind, raidx astragali, largehead atractylodes rhizome, common yam rhizome, Chinese angelica, cuttle bone and India madder root as the raw materials. The invention provides a preparation method and application for the medicinal composition. The medicinal composition of the invention has reasonable formula, corresponds to the traditional Chinese medical theory, has effects of clearing away heat and eliminating dampness, replenishing qi and strengthening the spleen and stopping leukorrhea, can be used for treating gynecologic inflammation, such as colpitis, cervicitis, pelvic inflammation, endometritis, adnexitis, episioitis, bartholinitis and the like and provides a novel use selection.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating gynecological inflammation, a preparation method and application thereof, and belongs to the field of medicines. Background technique [0002] Gynecological inflammation refers to diseases caused by infection of the female reproductive system. Mainly divided into vaginitis, cervicitis and pelvic inflammatory disease, endometritis, adnexitis, vulvitis, Bartholinitis. Because gynecological inflammation is a common and frequently-occurring disease in adult women, its clinical manifestations are also diverse, the etiology is complex and often accompanied by multiple serious complications, which have a great impact on women's life and work. The incidence of gynecological inflammatory diseases is quite high. In recent years, although the prevalence of gynecological inflammation has not changed much, it has remained high. High prevalence and high recurrence rate are the main characteristics ...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P15/00A61P15/02A61P29/00A61K35/56A61K35/618
Inventor 谢李李伟张文杰
Owner SICHUAN XUHUA PHARMA
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