Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine for treating proliferative vitreoretinopathy

A vitreoretinal and proliferative technology, used in drug delivery, sensory disease, drug combination, etc., can solve problems such as large systemic side effects, short duration of action, and large retinal damage.

Active Publication Date: 2010-08-11
XIAN BEILIN PHARMA
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are attempts to use glucocorticoids, antineoplastic drugs, retinoic acid and other drugs for treatment. The links of drug effects include inhibiting cell proliferation, anti-inflammation, inhibiting cellulose production, inhibiting the shrinkage of hyperplastic membranes to act on cell chairs, and gene therapy. However, since the occurrence of the disease is the result of the joint action of many factors and multiple links, these local medicines have a short action time, a single effect, great damage to the retina, and large systemic side effects, so most of them have not been used clinically.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine for treating proliferative vitreoretinopathy
  • Traditional Chinese medicine for treating proliferative vitreoretinopathy
  • Traditional Chinese medicine for treating proliferative vitreoretinopathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Leech 62.5g Triangle 187.5g Hawthorn 250g Kelp 250g Seaweed 250g

[0077] Mix Chinese herbal medicines, crush 1 / 3 of the Chinese herbal medicines into fine powder, add water to the other part of the prescription and decoct twice, 2.0 hours each time, 8 times the amount of water for the first time, 10 times the amount of water for the second time, and filter the decoction After that, the filtrates were combined and set aside; the above two filtrates were combined, concentrated under reduced pressure to a relative density of 1.07 to 1.09 (50°C), allowed to cool to room temperature, and slowly added ethanol to make the alcohol content reach 70%, fully stirred, and allowed to stand After 18 hours, filter, and decompress the filtrate (-0.085Mpa, 70-80°C) to recover ethanol until there is no alcohol smell, dilute the medicinal solution with water to a relative density of 1.03-1.05 (20°C), spray dry to obtain dry powder; add fine powder , starch, sucrose, magnesium stearate an...

Embodiment 2

[0079] Leech 125g Triangle 375g Hawthorn 500g Kelp 500g Seaweed 500g.

[0080] The medicine in the prescription is decocted twice with water, 2.0 hours each time, 8 times the amount of water for the first time, and 10 times the amount of water for the second time, filter the decoction, combine the filtrates, and set aside; combine the above two filtrates, concentrate under reduced pressure When the relative density is 1.07~1.09 (50°C), let cool to room temperature, slowly add ethanol to make the alcohol content reach 70%, fully stir, let stand for 18 hours, filter, and the filtrate is decompressed (-0.085Mpa, 70~ 80°C) to recover ethanol until there is no alcohol smell, add water to dilute the medicinal solution to a relative density of 1.03-1.05 (20°C), spray dry to obtain a dry powder, add fine powder, starch, sucrose, magnesium stearate and microcrystalline cellulose, mix Uniform, dry granulation, drying, granulation, capsules.

Embodiment 3

[0082] Leech 187.5g Triangle 562.5g Hawthorn 750g Kelp 750g Seaweed 750g.

[0083] Mix Chinese herbal medicines, crush 2 / 3 Chinese herbal medicines into fine powder, add water to the other part of the prescription and decoct twice, 2.0 hours each time, 8 times the amount of water for the first time, 10 times the amount of water for the second time, and filter the decoction After that, the filtrates were combined and set aside; the above two filtrates were combined, concentrated under reduced pressure to a relative density of 1.07 to 1.09 (50°C), allowed to cool to room temperature, and slowly added ethanol to make the alcohol content reach 70%, fully stirred, and allowed to stand After 18 hours, filter, and decompress the filtrate (-0.085Mpa, 70-80°C) to recover ethanol until there is no alcohol smell, dilute the medicinal solution with water to a relative density of 1.03-1.05 (20°C), spray dry to obtain dry powder, add fine powder , starch, sucrose, magnesium stearate and mic...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine for treating proliferative vitreoretinopathy, which is prepared from leech, trigone, hawthorn, kelp, seaweed and other traditional Chinese medicines as raw materials.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation composition, in particular to a traditional Chinese medicine prescription for treating proliferative vitreoretinopathy. Background technique [0002] Proliferative vitreoretinopathy is a kind of lesion that causes traction retinal detachment due to the proliferation of retinal pigment epithelial cells, fibroblasts, glial cells, macrophages, etc., as well as the deposition and shrinkage of collagen tissue. [0003] At present, there are attempts to use glucocorticoids, antineoplastic drugs, retinoic acid and other drugs for treatment. The links of drug effects include inhibiting cell proliferation, anti-inflammation, inhibiting cellulose production, inhibiting the shrinkage of hyperplastic membranes to act on cell chairs, and gene therapy. However, since the occurrence of the disease is the result of the joint action of many factors and multiple links, these local medicines have a short...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/902A61K9/00A61P27/02A61K35/62
Inventor 付彬王明芳黄小华张浩
Owner XIAN BEILIN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com