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Chinese medicinal composition granules and preparation method thereof

A composition and granule technology, which is applied in the field of traditional Chinese medicine composition granules and its preparation, can solve the problems of incomplete compliance with the theory of traditional Chinese medicine, inconvenient long-term use, and inability to completely replace them, and achieve convenient carrying and taking methods and convenient taking , to overcome the effect of poor stability

Active Publication Date: 2010-10-06
ZHONGSHAN ZHONGZHI PHARMA GRP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional decocting tablets are inconvenient for long-term use due to the trouble of decocting
However, because the extract granules of traditional Chinese medicine slices are extracted with solvents from the secondary metabolites in the slices of Chinese medicine, and some chemical components are artificially discarded, it does not fully conform to the theory of traditional Chinese medicine, so it cannot completely replace traditional slices of medicine in clinical application of traditional Chinese medicine.

Method used

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  • Chinese medicinal composition granules and preparation method thereof
  • Chinese medicinal composition granules and preparation method thereof
  • Chinese medicinal composition granules and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0031]Take American ginseng, Panax notoginseng, Dendrobium, and Salvia miltiorrhiza crude medicinal materials, sort and remove impurities mixed therein, and dry to obtain clean medicinal materials. Take the selected clean medicinal materials, and ultrafinely pulverize them into wall-broken powders with a particle size of D90=20 μm. In terms of parts by weight, take 6 parts of American ginseng broken wall powder, 9 parts of Panax notoginseng broken wall powder, 12 parts of Dendrobium broken wall powder, and 15 parts of Danshen broken wall powder, mix well, and adopt Co60 with an irradiation dose of 8kGy. After sterilizing by irradiation method, soft materials were made with 30vol% aqueous ethanol respectively, granulated by a granulator with a 10-mesh sieve, and then dried at 60°C to obtain unscreened traditional Chinese medicine granules; The sieved traditional Chinese medicine granules are sized by a granulator, so that the particle size of the granules is 20 meshes, accounti...

Embodiment 2

[0033] Take American ginseng, Panax notoginseng, Dendrobium, and Salvia miltiorrhiza crude medicinal materials, sort and remove impurities mixed therein, and dry to obtain clean medicinal materials. Take the selected clean medicinal materials, and ultrafinely pulverize them into wall-broken powders with a particle size of D90=50 μm. In terms of parts by weight, take 5 parts of American ginseng broken wall powder, 20 parts of Panax notoginseng broken wall powder, 20 parts of dendrobium broken wall powder, and 42 parts of Danshen broken wall powder, mix well, and adopt Co60 with an irradiation dose of 8kGy After sterilizing by irradiation method, use 40vol% aqueous ethanol to make soft materials respectively, pass through a granulator with a 30-mesh sieve, and then dry at 60°C to obtain unscreened traditional Chinese medicine granules; The sieved traditional Chinese medicine granules are sized by a granulator, so that the particle size of the granules is 40 mesh, accounting for ...

Embodiment 3

[0035] Take American ginseng, Panax notoginseng, Dendrobium, and Salvia miltiorrhiza crude medicinal materials, sort and remove impurities mixed therein, and dry to obtain clean medicinal materials. Take the selected clean medicinal materials, and ultrafinely pulverize them into wall-broken powders with a particle size of D90=75 μm. In terms of parts by weight, take 6 parts of American ginseng broken wall powder, 6 parts of Panax notoginseng broken wall powder, 12 parts of dendrobium broken wall powder, and 18 parts of Danshen broken wall powder, mix well, and use Co60 with an irradiation dose of 8 kGy. After sterilizing by irradiation method, use 50vol% aqueous ethanol to make soft materials respectively, pass through a granulator with a 10-mesh sieve, and then dry at 80°C to obtain unscreened traditional Chinese medicine granules; The sieved traditional Chinese medicine granules are sized by a granulator, so that the particle size of the granules is 20 meshes, accounting for...

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Abstract

The invention relates to Chinese medicinal composition granules and a preparation method thereof. The Chinese medicinal composition granules comprise the following ruptured powder in part by weight: 3 to 18 parts of American ginseng ruptured powder, 1 to 24 parts of pseudo-ginseng ruptured powder, 6 to 36 parts of dendrobium ruptured powder, and 9 to 45 parts of root of red-rooted salvia ruptured powder, wherein the granularity D90 of the ruptured powder is between 5 and 75 mu m. The invention also provides a method for preparing the Chinese medicinal composition granules. The method comprises the following steps of: uniformly mixing the American ginseng ruptured powder, pseudo-ginseng ruptured powder, dendrobium ruptured powder, and root of red-rooted salvia ruptured powder of which the D90 is between 5 and 75 mu m; preparing a soft material by adopting aqueous ethanol at the concentration of over 20 vol percent; and after granulating by using a granulator with 10 to 30 meshes, drying and finishing the granules to obtain the Chinese medicinal composition granules. The Chinese medicinal composition granules are applied to preventing and regulating human cardiac-cerebral vascular system diseases and sub-health state such as weak immunity and fatigability, have the obvious advantages of high medical effect, high quality uniformity, convenient carrying and administration, safety, reliability, and the like, and can meet the requirement on modern fast-paced lifestyle.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and more specifically relates to a traditional Chinese medicine composition granule with certain preventive and regulating effects on human cardiovascular and cerebrovascular system diseases, decreased immunity and fatigue-prone sub-health state and a preparation method thereof. Background technique [0002] Sub-health is caused by low immunity of the human body. It is an intermediate state between health and disease. Positive indicators cannot be detected by using modern instruments or detection methods, or although some indicators have changed, but Has not yet reached the diagnostic criteria of Western medicine disease. This state between health and disease is called "sub-health state". If this state is not intervened in time, it may further develop into a disease. For example, cardiovascular and cerebrovascular diseases and liver injury diseases are relatively common at present. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/16A61P9/00A61P37/04A61P39/00
Inventor 成金乐徐吉银陈勇军
Owner ZHONGSHAN ZHONGZHI PHARMA GRP
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