Gas atomization toxicant exposure box

Abstract

The invention relates to a gas atomization toxicant exposure box which is characterized by comprising a transparent box body, wherein the inner space of the box body is divided into a plurality of compartments by a spacing plate; a gas dispersion plate is arranged above the compartments, and breather holes are overspread on the gas dispersion plate; a box cover is arranged at the top of the box body; a gas inlet and a gas outlet are respectively arranged in the center position and the corner position of the box cover; the gas inlet is connected with an ultrasonic atomizer arranged outside the box body; a carbon dioxide sensor and an oxygen sensor are arranged in the box cover; the output ends of the carbon dioxide sensor and the oxygen sensor are connected with a signal amplification system; the output end of the signal amplification system is connected with a signal collector; the output end of the signal collector is connected with a computer; and a gas concentration monitoring module is prearranged in the computer. The invention has artful structural design and low cost, the prepared related animal models are scientific and reasonable and closer to the changes in human diseases, and the invention can be widely used in the preparation processes of various animal models.

Description

technical field [0001] The invention relates to a poison exposure box, in particular to a gas atomization poison exposure box for preparing experimental animal (rats, mice and guinea pigs) asthma models. Background technique [0002] Asthma is a world-recognized medical problem, listed by the World Health Organization as one of the four major chronic diseases. Repeated attacks of asthma can cause other diseases such as chronic obstructive pulmonary emphysema and lung injury, which will seriously endanger the health of the body. Therefore, research on the pathogenesis and treatment of asthma is a very important topic, and the preparation of standardized and scientific animal models is a necessary condition for scientific research. At present, the gas atomization poisoning boxes used to make animal asthma models at home and abroad are generally ordinary wooden boxes or plexiglass boxes. During the experiment, the animals are placed in the box, usually 6 to 10 experimental an...

AI Technical Summary

Problems solved by technology

Since multiple animals are placed in one space at the same time, they tend to get together. Therefore, the atomized gas containing antigenic substances inhaled by each experimental animal will be uneven.

At the same time, as the experiment progresses, the oxygen content in the box will gradually decrease, and the carbon dioxide content will gradually increase, but they cannot be detected by the experimenters in time, and measures should be taken.

Therefore, the current devices and methods for preparing animal asthma models are not scientific and standardized, often resulting in the failure of preparing experimental animal models

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