Use of ampelopsin in preparation of healthcare food and medicaments for protecting vascular endothelial cells

A technology for protecting endothelial cells and blood vessels, which is applied in the field of health food and pharmaceuticals, and can solve the problems of no staphylococcus

Inactive Publication Date: 2011-05-11
任启生 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But so far, there is no report on the application of staphylophyll in the preparation of health food and medicine for protecting vascular endothelial cells

Method used

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  • Use of ampelopsin in preparation of healthcare food and medicaments for protecting vascular endothelial cells

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The snake grape is taken, and the conventional extraction method is used to extract and purify the snake staphylophyllin, and it is divided into 0.4g / bottle powder injection ampoules or injections.

Embodiment 2

[0025] Get vine tea and extract the staphylophyllin extract conventionally, without purification, after content determination, get 340g staphylophyllin extract, add 30g vitamin E, 30g vitamin C, add auxiliary material according to the conventional method, granulate, mix, Sieve, add glidant magnesium sulfate, talcum powder, process into tablet according to tablet routine production process, make staphylophyll tablet, each tablet contains staphylocoxine 200mg.

Embodiment 3

[0027] Take 10kg of sucrose grapes, extract twice by conventional ethanol extraction method, combine the ethanol extracts and concentrate to a clear paste with a relative density of 1.35-1.38, add an appropriate amount of sucrose powder, mix well, and make granules.

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PUM

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Abstract

The invention discloses the use of ampelopsin in the preparation of healthcare food and medicaments for protecting vascular endothelial cells. In the invention, purified ampelopsin or unpurified ampelopsin-containing extract is prepared into pharmaceutically allowable preparations for oral taking, injection or external application. The ampelopsin protects the vascular endothelial cells by reducing peroxidation of lipid, resisting oxidative damage and other actions, so as to prevent and treat cardiovascular and cerebrovascular diseases caused by endothelial cell injury, such as atherosclerosis, hypertension and cardiac-cerebral thrombosis.

Description

[0001] Research areas: [0002] The present invention relates to the application of staphyloin in the fields of health food and pharmacy, in particular to the application of staphylocin in the preparation of health food and medicine for protecting vascular endothelial cells. Background technique: [0003] Vascular endothelial cells (VEC) are a single layer of flat cells lining the inner surface of the cardiovascular vessel. Vascular endothelial cells not only have the functions of selective permeability, anti-thrombosis, regulation of vascular tension, promotion of capillary formation and production of blood cell adhesion factors, but also the source and target organ of various vasoactive substances, cytokines and growth factors. [0004] The injury of vascular endothelial cells is closely related to various cardiovascular diseases (such as atherosclerosis, hypertension, thrombosis, etc.). Taking thrombus as an example, endothelial cells have an antithrombotic effect under p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/30A61K31/352A61P9/00A61P9/10A61P9/12A61P7/02A23L33/10
Inventor 任启生宋新荣陈黄实
Owner 任启生
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