Nano-scale liquid composite vitamin preparation

A technology of complex vitamins and nano-scale liquids, which is applied in the direction of drug combinations, active ingredients of hydroxyl compounds, active ingredients of heterocyclic compounds, etc., can solve the problems of unstable bioavailability of vitamin preparations, achieve improved pharmacokinetic stability, High utilization rate, solve the effect of reducing potency

Inactive Publication Date: 2011-05-11
TIANJIN RINGPU BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a nano-scale liquid compound vitamin preparation suitable for direct drinking water of animals and its preparation method

Method used

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  • Nano-scale liquid composite vitamin preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A. Dissolve 0.5g of vitamin A, 0.5g of vitamin D, 0.5g of vitamin E, and 10g of polysorbate-80 in 10ml of glycerin to prepare liquid A;

[0031] B. Dissolve vitamin C1g, vitamin B10.5g, and vitamin B60.5g in 57ml of water, stir evenly, and make liquid B;

[0032] C. Pour liquid B into liquid A while stirring, and stir evenly;

[0033] D. The above mixed solution is homogenized by a high-pressure homogenizer under a pressure of 60Mpa, filled, and obtained.

Embodiment 2

[0035] A. Dissolve 0.3g of vitamin A, 0.3g of vitamin D, 0.3g of vitamin E, and 0.6g of propylene glycol diethyl ester in 40ml of polyethylene glycol respectively to form A solution;

[0036] B. Combine vitamin C1g, vitamin B 1 0.5g, vitamin B 6 Dissolve 0.5g in 57ml of water and stir evenly to form B solution;

[0037] C. Pour liquid B into liquid A while stirring, and stir evenly;

[0038] D. The above mixed solution is homogenized by a high-pressure homogenizer under a pressure of 50Mpa, filled, and obtained.

Embodiment 3

[0040] A. Dissolve 0.8g of vitamin A, 0.6g of vitamin D, 0.3g of vitamin E, and 1g of polyvinyl alcohol in 50ml of polyethylene glycol respectively to form A solution;

[0041] B. Combine vitamin C1g, vitamin B 1 0.5g, vitamin B 6 Dissolve 0.5g in 47ml of water, stir evenly, and it is liquid B;

[0042] C. Pour liquid B into liquid A while stirring, and stir evenly;

[0043] D. The above mixed solution is homogenized by a high-pressure homogenizer under a pressure of 70Mpa, filled, and obtained.

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Abstract

The invention relates to a nano-scale liquid composite vitamin preparation and a preparation method thereof. The preparation overcomes the defects of poor stability, low bioavailability and the like of common liquid vitamins, and has good bioavailability and good stability.

Description

technical field [0001] The invention belongs to the field of veterinary drugs, and in particular relates to a nano-scale liquid multivitamin preparation suitable for direct drinking water of animals and a preparation method thereof. Background technique [0002] Vitamins, also known as vitamins, are a class of organic substances necessary to maintain the life activities of the body, and are also important active substances to maintain the health of the body. The content of vitamins in the body is very small, but it plays an important role in the growth, metabolism and development of the body. Although the chemical structures and properties of various vitamins are different, they have the following things in common: ①Vitamins exist in food in the form of provitamins (vitamin precursors) ②Vitamins are not components of body tissues and cells. It does not produce energy, and its role is mainly to participate in the regulation of the body's metabolism ③Most vitamins cannot be s...

Claims

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Application Information

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IPC IPC(8): A61K31/59A61K31/51A61K31/4415A61K31/375A61K31/355A61K31/07A61P3/02A61P37/00
Inventor 富艳玲夏雪林刘爱玲
Owner TIANJIN RINGPU BIO TECH
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