14 results about "Vitamin Preparations" patented technology

This invention discloses a vitamin preparation stability testing system and method, belonging to the field of preparation testing technology. This invention improves the accuracy and coverage of vitamin preparation stability monitoring, comprehensively capturing complex degradation state changes and stability differences on the preparation surface. It significantly improves the quality assurance efficiency and product reliability level during the vitamin preparation factory testing process. It constructs a dynamic weak point identification mechanism, effectively preventing the omission of weak concentrated areas by fixed-area monitoring, avoiding assessment bias and quality omissions caused by subjective judgment, realizing intelligent allocation and differentiated investment of quality screening resources, effectively improving the pertinence and implementation effect of the deviation batch judgment scheme, identifying concentrated abnormal degradation areas that threaten preparation stability, and ensuring a high degree of consistency between quality control measures and actual degradation failure risks.

The invention discloses a quality control device and method for multivitamins for injection, and relates to the technical field of vitamin preparation, the technical key points are as follows: the quality control device comprises a sample collection mechanism, a liquid guide tube, an electromagnetic metering valve and a test tube transfer assembly; the sample pretreatment mechanism is provided with a stirring assembly and an automatic dilution assembly, and the automatic dilution assembly comprises a high-precision capacity metering device and a flow control valve; the high performance liquid chromatography detection mechanism is provided with a plurality of chromatographic columns, a mobile phase conveying system containing a high-pressure pump, a detection wavelength adjusting device, an automatic sample injector and a data processing system; the atomic absorption spectrometry detection mechanism is provided with a hollow cathode lamp; the infrared spectroscopy detection mechanism is provided with an interferometer and a detector; the quality control process management system is constructed based on a programmable logic controller and an industrial computer and is provided with a state indicator lamp and an alarm device; the online quality monitoring system comprises a data processing unit and a network communication unit; according to the invention, convenience can be ensured, and efficiency and automation degree are improved.

The invention discloses a vitamin E preparation production line and a production method thereof.The vitamin E preparation production line comprises a first feeding device, a first mixing device, a first air cooling device and a first screening device, the first feeding device is arranged above the first mixing device, the first air cooling device is arranged below the first mixing device, and the first screening device is arranged below the first mixing device; the first screening device is arranged below the first air cooling device; the first feeding device comprises a feeding oil tank, a first stock bin and a first metering tank, the feeding oil tank is arranged above the first metering tank, the first stock bin is arranged on one side of the first metering tank, the first mixing device comprises a first mixing machine, and the first metering tank and the first stock bin are both connected with the first mixing machine. According to the vitamin E preparation production line and the production method thereof provided by the invention, the vitamin E preparation can be obtained through blanking of the first metering tank and the first stock bin, mixing of the first mixer and cooling and screening treatment, and the efficiency is high.

The application provides a method for determining the content of biotin in a complex vitamin preparation. The method comprises detecting the content of biotin by high performance liquid chromatography, wherein a surface porous reversed-phase chromatographic column with modified amide groups is used for gradient elution, and a mobile phase A and a mobile phase B are used, the mobile phase A comprises potassium dihydrogen phosphate buffer and acetonitrile, and the mobile phase B comprises acetonitrile. The method can realize the non-interference separation and detection of the content of biotin in the complex vitamin preparation with a complex matrix, and has the advantages of simplicity, good specificity, rapid analysis, accurate result and sensitive response.

The invention belongs to the technical field of food, and particularly relates to recombined soup-stock and a preparation method thereof. The recombined soup-stock is prepared from the following raw materials in parts by weight: 0-1 part of an amino acid mixed preparation, 0-0.5 part of a vitamin preparation, 10-20 parts of animal fat, 0-2 parts of a food additive and the balance of water, wherein the total weight is 100 parts; wherein the amino acid mixed preparation is formed by mixing a water-soluble amino acid aqueous solution and a micro / low water-soluble amino acid grease dispersion liquid according to any proportion, and the vitamin preparation is formed by mixing a water-soluble vitamin aqueous solution and a fat-soluble vitamin grease solution according to any proportion. The food additive comprises an emulsifier, an antioxidant and edible essence. By utilizing the methods, the recombined soup-stock which is unique in flavor, good in taste, easy to industrially produce and very good in practical value is prepared.

The application relates to the technical field of veterinary drugs, and discloses a compound vitamin preparation, a preparation method thereof and application.The compound vitamin preparation comprises a water phase and an oil phase; the water phase comprises the following components in parts by weight: 1-3 parts of hydroxypropyl chitosan, 0.5-2 parts of vitamin C and 50 parts of water; and the oil phase comprises the following components in parts by weight: 1.1-5.5 parts of fat-soluble vitamins and 27.6-41.4 parts of an emulsifying system.The above technical scheme solves the problem that vitamin C in the vitamin preparation in the prior art is easy to be oxidized.

The invention relates to the technical field of vitamin preparation, and provides a vitamin K2 extraction device and method.The vitamin K2 extraction device comprises a fermentation tank, the fermentation tank is fixedly installed on a fixed rack, a feeding port is formed in the top of the fermentation tank, the output end of the fermentation tank is communicated with a discharging pipe, a control valve is fixedly installed on the discharging pipe, and the control valve is connected with the feeding port. The stirring shaft is rotatably mounted in the fermentation tank, the sampling barrel is fixedly mounted on the side part of the fermentation tank, the sampling assembly is mounted on the sampling barrel, the driving assembly is mounted at the top of the fermentation tank, and the ventilation assembly is mounted at the top of the fermentation tank; the technical problem that in the prior art, when fermentation liquor is sampled, due to the fact that the fermentation liquor retained in a sampling pipe is difficult to reflect the real change condition in a fermentation tank, the authenticity of the taken-out sample is affected, and the judgment on the fermentation condition is affected is solved.

FIELD: veterinary medicine.SUBSTANCE: used in the treatment of purulent inflammation of the base of the skin of the cattle hooves. Orthopedic trimming of the hooves is performed, devitalized tissue is removed, and an orthopedic block is glued to the healthy toe of the animal on the same limb. An even layer of Vet-Kopem ointment is applied to the affected area. The ointment consists of the following components, wt.%: egotsin 20 – 47.6; “АСД-3ф” – 18.9; vitamin preparation Trivit – 14.7; iodinol – 8.2; dioxidine – 4.2; petroleum jelly – 6. Next, the area is covered with a gauze napkin, after which bandage is applied with a veterinary self-fixing elastic bandage. The procedure is repeated after 3-4 days in the first week, and once a week in the following days until local damage to the skin base in the hooves of cattle is completely healed.EFFECT: provision of an increase in the therapeutic effectiveness of the treatment of purulent inflammation of the base of the skin of the hooves of cattle and an enhancement of the antibacterial, antiseptic, and anti-inflammatory effect, resulting in a reduction in the healing time and restoration of the productive performance of animals.1 cl, 2 dwg, 1 tbl

The application relates to a choline bitartrate solid dispersion, a preparation method and application thereof in the technical field of pharmaceutical preparations. The choline bitartrate solid dispersion is prepared by a melting method; the preparation raw materials of the choline bitartrate solid dispersion include the following components in percentage by mass: 20-50 wt% of choline bitartrate, 20-50 wt% of a sugar alcohol, 10-30 wt% of glycerin monostearate and 0.1-5 wt% of modified starch. In the solid dispersion prepared by the melting method, the choline bitartrate can be finely and amorphously dispersed and distributed in inert solid carriers such as the sugar alcohol and glycerin monostearate, so that the moisture absorption prevention effect is improved, and the bad smell of the choline bitartrate is effectively covered. When the solid dispersion is applied to the preparation of choline bitartrate preparations and composite vitamin preparations containing choline bitartrate, the stability of the preparations can be obviously improved.

The invention discloses degerming and filtering equipment and method for multivitamins for injection, and relates to the technical field of vitamin preparation.The degerming and filtering equipment is technically characterized in that the degerming and filtering equipment comprises a filtering box, the two sides of the filtering box are connected with a liquid inlet pipe and a liquid outlet pipe respectively, the liquid inlet pipe is connected with mixing equipment of multivitamin solutions, and the liquid outlet pipe is connected with filling equipment; a plurality of filling frames are arranged in the filter box, the filling frames are filled with filter units, the two faces of each filling frame are attached to each other, each filter unit is one of an activated carbon layer or a filter membrane, and the surface of each filter unit is coated with a silver ion antibacterial coating; according to the invention, the filtering efficiency and effect can be improved.

The invention discloses a preparation device and a preparation method of multivitamins for injection, and relates to the technical field of vitamin preparation, and the technical key points are as follows: the preparation device comprises a nitrogen charging device for supplying nitrogen; the first liquid preparation tank is communicated with the nitrogen charging device, is internally provided with a heating assembly and is used for preparing oxygen-free injection water; the second liquid preparation tank is communicated with the nitrogen charging device, a second stirring assembly is arranged in the second liquid preparation tank, and fat-soluble vitamins and the like are mixed to prepare a micelle solution; a third stirring assembly is arranged in the third liquid preparation tank, and a fat-soluble vitamin solution is independently prepared; a fourth stirring assembly is arranged in the fourth liquid preparation tank, and the fourth liquid preparation tank is used for preparing a water-soluble vitamin solution and is connected with the second liquid preparation tank; the PH adjusting device is connected with the fourth liquid preparation tank; the injection water supply device is arranged between the first liquid preparation tank and the fourth liquid preparation tank and is used for supplementing water and fixing the volume; the degerming and filtering device is connected with a liquid outlet of the fourth liquid preparation tank and filling equipment; according to the invention, convenience can be ensured, and efficiency and automation degree are improved.

The invention provides a vitamin K1 injection package preparation method and a vitamin K1 injection package, the vitamin K1 injection package preparation method comprises the steps of filling, nitrogen filling, plug adding and rod screwing, in the nitrogen filling step, sterile nitrogen is filled into a glass needle tube, oxygen in the glass needle tube is removed to be 2.0% or below, in the plug adding step, the glass needle tube is vacuumized, so that a piston is sucked into the glass needle tube, and the rod screwing is performed. The headspace volume is controlled to be 0.1 to 0.2 ml. According to the present invention, the total impurity amount and the maximum single impurity content of the vitamin K1 preparation in the glass needle tube can be maintained at the low level after the long-term placement, and the potential secondary pollution risk is avoided by using the glass needle tube packaging form.

This invention belongs to the field of feed additive preparation technology, specifically disclosing a compound vitamin preparation, its preparation method, and its application. The compound vitamin preparation comprises the following components by weight: 5-10 parts of Sophora japonica flower extract, 1-2 parts of vitamin A, 1-2 parts of vitamin C, 1-2 parts of vitamin E, and 20-30 parts of porous starch. This invention discloses a compound vitamin preparation, its preparation method, and its application. This compound vitamin preparation can increase animal body weight and average daily weight gain, reduce intestinal permeability indicators, improve intestinal barrier function, and promote animal growth and development.