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Chinese medicinal preparation for treating acute upper respiratory tract infection and preparation method thereof

A technology for upper respiratory tract and traditional Chinese medicine preparations, which can be used in antiviral agents, medical formulas, respiratory diseases, etc., and can solve problems such as slow effect

Active Publication Date: 2012-08-29
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Overcoming method, reconciliation method, promoting blood circulation and removing blood stasis method, clearing qi and cooling camping method, promoting tonality and removing dampness, etc. However, the current traditional Chinese medicine treatment of viral upper respiratory tract infection is generally slow to take effect, and it has not been able to quickly reduce fever and improve clinical symptoms of the upper respiratory tract. traditional Chinese medicine

Method used

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  • Chinese medicinal preparation for treating acute upper respiratory tract infection and preparation method thereof
  • Chinese medicinal preparation for treating acute upper respiratory tract infection and preparation method thereof
  • Chinese medicinal preparation for treating acute upper respiratory tract infection and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Weigh Chinese herbal pieces: notopterygium 10g, peppermint 10g, Bupleurum 10g, scutellaria baicalensis 10g, Artemisia annua 10g, gypsum 30g, Daqingye 15g, Commelina 15g and raw licorice 5g.

[0020] Combine peppermint, Artemisia annua and notopterygium, add 12 times the amount of water, soak for 0.5 hours, distill until the volatile oil is distilled off, separate and collect the essential oil, and use the medicinal residue for later use.

[0021] The gypsum is first decocted for 30 minutes; combine Bupleurum, Scutellaria, Folium Folium, Commelina, and Raw Licorice, soak in water for 20 minutes, then add to the gypsum decoction, add 10 times the amount of water for the first time, and decoct for 0.5 hours. Add 8 times the amount of decoction for the second time for 0.5 hour, merge the decoction, filter, and the filtrate is concentrated to a clear paste with a relative density of 1.15 (density value at 60°C), and ethanol is added until the alcohol content reaches 60% (weig...

Embodiment 2

[0024] Weigh the decoction pieces: notopterygium 8g, mint 8g, Bupleurum 12g, scutellaria baicalensis 10g, Artemisia annua 8g, gypsum 40g, Folium 12g, Commelina 12g and raw licorice 3g.

[0025] The preparation method is the same as in Example 1 to obtain Shanggan granules.

[0026] As determined by high performance liquid chromatography, the content of baicalin in the granules was 21 mg / g.

Embodiment 3

[0028] Weigh the decoction pieces: Notopterygium 14g, Mint 12g, Bupleurum 12g, Scutellaria baicalensis 12g, Artemisia annua 12g, Gypsum 40g, Folium 18g, Commelina 15g and Raw licorice 6g.

[0029] The preparation method is the same as in Example 1 to obtain Shanggan granules.

[0030] As determined by high performance liquid chromatography, the content of baicalin in the granules was 20 mg / g.

[0031] Example 3

[0032] Weigh raw materials: Notopterygium 14g, Peppermint 12g, Bupleurum 12g, Scutellaria baicalensis 12g, Artemisia annua 12g, Gypsum 40g, Folium 18g, Commelina 15g, Raw licorice 6g.

[0033] The preparation method is the same as in Example 1 to obtain Shanggan granules.

[0034] As determined by high performance liquid chromatography, the content of baicalin in the granules was 20 mg / g.

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Abstract

The invention relates to a Chinese medicinal preparation for treating acute upper respiratory tract infection. The Chinese medicinal preparation is prepared from the following Chinese medicinal decoction pieces in part by weight: 6 to 14 parts of notopterygium root, 6 to 12 parts of mint, 8 to 12 parts of bupleurum falcatum, 9 to 12 parts of baikal skullcap root, 8 to 12 parts of sweet wormwood, 15 to 40 parts of gypsum, 12 to 18 parts of indigowoad leaves, 10 to 15 parts of common dayflower herb and 2 to 6 parts of raw liquorice. The processes of decocting, purifying, concentrating, drying and the like are determined according to the properties of different Chinese medicinal decoction pieces and properties of effective ingredients or parts; and the extraction rate and the content of baicalin are used as indexes, and the orthogonal test is adopted for determining. Volatile oils in the mint, the sweet wormwood and the notopterygium root are effective ingredients, and are extracted respectively and added when a solid preparation is formed finally. The preparation can be used for treating fever caused by acute upper respiratory tract infection, can effectively resist virus, brings down fever quickly, and improves pharyngalgia, cough and other upper respiratory clinical symptoms.

Description

technical field [0001] The invention relates to an antipyretic traditional Chinese medicine preparation for treating viral upper respiratory tract infection. Background technique [0002] Acute upper respiratory tract infection (acute upper respiratory tract infection) is referred to as Shanggan for short. The main pathogens are viruses, and a few are bacteria. Spread through the respiratory tract, such as the patient's sneezing and virus-containing droplets through the air, or through contact with contaminated hands and utensils. Upper respiratory tract infection is a general term for acute inflammation from the nostrils to the lower edge of the cricoid cartilage, including the nasal cavity, pharynx or larynx. Most of the pathogens that cause the flu are a variety of viruses that exist widely in nature, and the viruses have variability, and healthy people can also carry them, and the human body’s immunity to them after infection is weak and short-lived, and there is no cro...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/539A61P11/00A61P31/12A61K33/06
Inventor 奚肇庆周勤妹熊宁宁刘志辉李七一
Owner JIANGSU KANION PHARMA CO LTD
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