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Chinese medicinal preparation for treating uterine fibroid and preparation method thereof

A technology for traditional Chinese medicine preparations and uterine fibroids, which is applied in the field of pharmaceutical preparations, can solve problems such as affecting hormone secretion levels, disrupting physiological balance, prolonging recovery period, etc., and achieves the effects of simplifying prescriptions, reducing operation steps, and improving extraction efficiency.

Active Publication Date: 2012-10-10
SHANDONG BUCHANG SHENZHOU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The clinical treatment of uterine fibroids generally adopts mifepristone, androgen, tripterygium glycosides and other drugs and surgical treatment. Although the uterine fibroids shrink after the above drug treatment, the side effects are large, which usually affect the normal internal organs of the human body. The level of hormone secretion destroys the normal physiological balance of the human body, and different degrees of masculine characteristics appear. After stopping the drug, the fibroids grow again, and it is difficult to completely cure them
The effect of surgical treatment is good, but surgical treatment brings greater trauma to the patient, prolongs the recovery period, and the patient's ability to accept it is poor

Method used

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  • Chinese medicinal preparation for treating uterine fibroid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] (1) Take 128g of Rhizoma Cyperi, 128g of Cortex Moutan, 64g of Atractylodes Rhizome, 64g of Evodia rutaecarpa, soak in 8 times the amount of water, steam distill for 2 hours to extract the volatile oil, collect the volatile oil, and wrap it with 2 times the amount of β-cyclodextrin for later use. After the liquid is filtered, it is used for later use, and the medicinal residue is kept for use;

[0051] (2) Take (1) traditional Chinese medicine residue, 210g of Hedyotis diffusa, 126g of Agrimony, and 64g of Codonopsis pilosula, add 8 times the amount of water, adjust the pH value of the water to 4.5, heat and extract, extract twice, each time for 1h, and combine the extracts, Filtrate, combine with the filtrate in (1), add ethanol to make the alcohol content reach 70%, refrigerate for 12 hours and centrifuge, concentrate the supernatant to recover ethanol until it has no alcohol smell, dry and pulverize it into 80-mesh fine powder for later use;

[0052] (3) get trigonum...

Embodiment 2

[0057] (1) Take 128g Cyperus cyperi, 128g cortex Moutan, 64g Atractylodes macrocephala, 64g Evodia rutaecarpa, soak in 12 times the amount of water, steam distill for 6 hours to extract the volatile oil, collect the volatile oil, and wrap it with 6 times the amount of β-cyclodextrin for later use. After the liquid is filtered, it is used for later use, and the medicinal residue is kept for use;

[0058] (2) Take (1) traditional Chinese medicine residue, 210g of Hedyotis diffusa, 126g of Agrimony, 64g of Codonopsis pilosula, add 12 times of water, adjust the pH value of the water to 6.5, heat and extract, extract twice, each time for 1h, and combine the extracts, Filtrate, combine with the filtrate in (1), add ethanol to make the alcohol content reach 90%, refrigerate for 36 hours and then centrifuge, concentrate the supernatant to recover ethanol until it has no alcohol smell, dry and pulverize it into a 120-mesh fine powder for later use;

[0059] (3) Get Sanleng 64g, Zedoary...

Embodiment 3

[0062] (1) Take 128g of Rhizoma Cyperi, 128g of Cortex Moutan, 64g of Atractylodes Rhizome, 64g of Evodia rutaecarpa, soak in 10 times the amount of water, steam distill for 6 hours to extract the volatile oil, collect the volatile oil, and wrap it with 4 times the amount of β-cyclodextrin for later use. After the liquid is filtered, it is used for later use, and the medicinal residue is kept for use;

[0063] (2) Take (1) traditional Chinese medicine residue, 210g of Hedyotis diffusa, 126g of Agrimony, 64g of Codonopsis pilosula, add 10 times of water, adjust the pH value of the water to 5.5, heat and extract, extract twice, each time for 1h, and combine the extracts, Filtrate, combine with the filtrate in (1), add ethanol to make the alcohol content reach 75%, refrigerate for 24 hours and then centrifuge, concentrate the supernatant to recover ethanol until it has no alcohol smell, dry and pulverize it into a 100-mesh fine powder for later use;

[0064] (3) Get Sanleng 64g, ...

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Abstract

The invention relates to a Chinese medicinal preparation for treating uterine fibroid and a preparation method thereof. The Chinese medicinal preparation is prepared from 210 weight parts of oyster shell, 128 weight parts of prepared nutgrass galingale rhizome, 64 weight parts of common burreed rhizome, 64 weight parts of zedoary, 64 weight parts of ground beeltle, 64 weight parts of szechuan tangshen root, 64 weight parts of largehead atractylodes rhizome, 64 weight parts of medcinal evodia fruit, 210 parts of spreading hedyotis herb, 126 parts of hairyvein agrimonia herb and bud and 128 parts of tree peony bark which serve as raw materials and are extracted and purified according to a certain process and pharmaceutically-acceptable auxiliary materials. The Chinese medicinal preparation has the characteristics of simple, feasible, safe and effective preparation process, and obvious pharmacological and medicinal effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating uterine fibroids and a preparation method thereof, belonging to the technical field of medical preparations. Background technique [0002] Uterine fibroids, also known as uterine fibroids, are the most common benign tumors of the female reproductive system. The incidence rate of women in the childbearing period is about 25%, accounting for about 51.87% of all benign tumors in women. Pain, inflammatory swelling, etc. caused by it is its common complication. Its most common clinical symptoms are: uterine bleeding, lower abdominal pain and dysmenorrhea, compression symptoms, increased vaginal secretions, anemia, and even infertility, which seriously affects women's health and daily work. May transform into a malignant tumor. [0003] At present, the etiology and pathogenesis of uterine fibroids are complicated. Classical studies believe that uterine fibroids are benign tumo...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P15/00A61K35/56A61K35/64A61K35/618
Inventor 赵涛
Owner SHANDONG BUCHANG SHENZHOU PHARMA
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