33results about How to "Embody innovation" patented technology

The invention discloses an SDN resource distribution method based on a two-sided market multihoming structure. The SDN resource distribution method based on the two-sided market multihoming structure comprises the steps that firstly, an SDN resource distribution frame is divided into a customer layer, a control layer and a retailer layer; secondly, after the customer layer receives application requests of different users, summarizes the application requests into a request information list and transmits the request information list to the control layer through a northbound interface; thirdly, the retailer layer transmits resource information to the control layer in real time through a southbound interface; fourthly, the control layer comprises a plurality of independent control platforms, each control platform receives the resource information from the retailer layer and sends the resource information and expense information of the control platforms to the customer layer, and the users in the customer layer carry out selection from the multiple control platforms according to the self needs; fifthly, each customer requires needed resources from the multiple control platforms, and carries out selection according to a resource cost-performance ratio provided by each control platform by using a resource combination strategy. The SDN resource distribution method based on the two-sided market multihoming structure meets the requirements for tasks of users, makes full use of network resources, and improves the reliability of the network.

Pre-cationic / cationic liposomal curcumin preparation for interventional treatment of liver cancer and preparation method thereof The present invention relates to a cationic / pre-cationic liposomal curcumin preparation for interventional treatment of liver cancer and a preparation method thereof. It is characterized in that, the medicine in the preparation is made from the following components: curcumin 1mg, egg yolk lecithin 3.0g, cholesterol 1.0g, octadecylamine 0.2g / [2-[[4-[(carboxymethyl)disulfide ]-1-iminobutyl]amino]ethyl]cholesteryl carbamate (CHETA) 0.05g, vitamin E 0.3g, pH 6.6 phosphate buffered saline solution 20mL. Preparation method: take egg yolk lecithin, cholesterol, octadecylamine / CHETA and vitamin E in a pear-shaped bottle, add 10 mL of ether, shake, and then add 5 mL of curcumin-containing absolute ethanol solution, and put it on a rotary evaporator at 35°C Evaporate to dryness to form a film, then add 20 mL of phosphate buffered saline solution with a pH value of 6.6, rotate for 20 minutes to dissolve the film, leave it for 3 hours to fully hydrate, sonicate for 3 minutes, and pass through a 0.22 μm filter membrane to obtain cationic / precationic liposomal curcumin . The two preparations are used to treat liver cancer through interventional administration, and have higher therapeutic effects and lower side effects on various stages of liver cancer.

The invention relates to luteolin-glycyrrhizic acid conjugated bovine serum albumin drug-loaded nanoparticles and a preparation and an application thereof. The luteolin-glycyrrhizic acid conjugated bovine serum albumin drug-loaded nanoparticles are a glycyrrhizic acid conjugated bovine serum albumin drug-loaded nanoparticles system through chemical modification of bovine serum albumin by glycyrrhizic acid, and then luteolin is coated in the glycyrrhizic acid conjugated bovine serum albumin drug-loaded nanoparticles system; wherein the glycyrrhizic acid conjugated bovine serum albumin drug-loaded nanoparticles having liver-targeting are taken as a carrier, and luteolin is taken as an anti-liver cancer bulk drug. The nanoparticles can improve the solubility, stability and targeting performance of luteolin and the drug-loaded nanoparticles to improve their bioavailability and anti-liver cancer efficacy. The encapsulation rate of the nanoparticles is increased to 30.33%. On an in-vitro cellular level, compared with GL-BSA-Lut-NPs by Lut, the drug-loaded nanoparticles have significantly increased water solubility, absorption, anti-tumor efficacy and the like.