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Preparation method of traditional Chinese medicine extract of decoction capable of invigorating spleen yang and tonifying stomach and application thereof

A technology of Shengyang Yiwei Decoction and its extract, which is applied in the field of traditional Chinese medicine, can solve the problems of taking, inconvenient to carry, large amount of taking, not suitable for processing, etc.

Pending Publication Date: 2018-11-06
湖北颐仁中医药研究总院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The medicine is gradually added to Wuqian"): and the traditional water extraction process parameters are not, it can be seen that the traditional process is rough, and it is inconvenient to take and carry, and the dosage is large, and it is not suitable for processing into other dosage forms

Method used

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  • Preparation method of traditional Chinese medicine extract of decoction capable of invigorating spleen yang and tonifying stomach and application thereof
  • Preparation method of traditional Chinese medicine extract of decoction capable of invigorating spleen yang and tonifying stomach and application thereof
  • Preparation method of traditional Chinese medicine extract of decoction capable of invigorating spleen yang and tonifying stomach and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Example 1 Water extraction method to prepare "Shengyang Yiwei Decoction" side Chinese medicine extract

[0043] Method 1: Take Astragalus, Pinellia, Ginseng, Licorice, Fangfeng, Paeoniae Alba, Notopterygium, Duhuo, Orange Peel, Poria, Alisma, Bupleurum, Atractylodes Rhizome, Coptidis, Ginger, and Jujube as raw materials, and use water as a solvent to extract the Said raw materials, the weight ratio of each raw material is astragalus: pinellia: ginseng: licorice: windproof: white peony: notopterygium: solitary: orange peel: poria cocos: Alisma: Bupleurum: Atractylodes macrocephala: coptis: ginger: jujube = 20:10: 10:10:5:5:5:5:4:3:3:3:3:2:2:2; cleanly select the above medicinal materials, weigh 200 kg of astragalus, 100 kg of pinellia, ginseng 100 kg, 100 kg of licorice, 50 kg of windproof, 50 kg of white peony, 50 kg of notopterygium, 50 kg of solitary, 40 kg of orange peel, 30 kg of poria cocos, 30 kg of Alisma, 30 kg of Bupleurum, 30 kg of Atractylodes macrocephala, 2...

Embodiment 2

[0046] Example 2 Alcohol extraction method to prepare "Shengyang Yiwei Decoction" prescription Chinese medicine extract

[0047] Method 1: Take Astragalus, Pinellia, Ginseng, Licorice, Fangfeng, Paeoniae Alba, Notopterygium, Duhuo, Orange Peel, Poria, Alisma, Bupleurum, Atractylodes Rhizome, Coptis Rhizome, Ginger, and Jujube as raw materials, and use 65% ethanol as a solvent The raw materials are extracted, and the weight ratio of each raw material is astragalus: pinellia: ginseng: licorice: windproof: white peony root: notopterygium: solitary life: orange peel: poria cocos: Alisma: Bupleurum: Atractylodes macrocephala: coptis: ginger: jujube = 20: 10:10:10:5:5:5:5:4:3:3:3:3:2:2:2; cleanly select the above-mentioned medicinal materials, weigh 200 kg of astragalus and 100 kg of pinellia according to the proportion , 100 kg ginseng, 100 kg licorice, 50 kg windproof, 50 kg white peony, 50 kg notopterygium, 50 kg eucalyptus, 40 kg orange peel, 30 kg poria cocos, 30 kg Alisma, 30 ...

Embodiment 3

[0050] Example 3 Preparation of "Shengyang Yiwei Decoction" prescription traditional Chinese medicine extract by water extraction and alcohol precipitation method

[0051] Method 1: Take Astragalus, Pinellia, Ginseng, Licorice, Fangfeng, Paeoniae Alba, Notopterygium, Duhuo, Orange Peel, Poria, Alisma, Bupleurum, Atractylodes Rhizome, Coptidis, Ginger, and Jujube as raw materials, and use water as a solvent to extract the Said raw materials, the weight ratio of each raw material is astragalus: pinellia: ginseng: licorice: windproof: white peony: notopterygium: solitary: orange peel: poria cocos: Alisma: Bupleurum: Atractylodes macrocephala: coptis: ginger: jujube = 20:10: 10:10:5:5:5:5:4:3:3:3:3:2:2:2; cleanly select the above medicinal materials, weigh 200 kg of astragalus, 100 kg of pinellia, ginseng 100 kg, 100 kg of licorice, 50 kg of windproof, 50 kg of white peony, 50 kg of notopterygium, 50 kg of solitary, 40 kg of orange peel, 30 kg of poria cocos, 30 kg of Alisma, 30 k...

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Abstract

The invention provides a preparation method of a decoction capable of invigorating spleen yang and tonifying stomach and application thereof. The decoction is derived from the decoctions capable of invigorating spleen yang and tonifying stomach in Treatise on Spleen and Stomach which is written by Li Dongyuan in Jin Dynasty and is abbreviated as Decoctions capable of Invigorating Spleen Yang and Tonifying Stomach in full texts of patents. The invention provides the following six preparation methods: (1) a water extraction method; (2) an alcohol extraction method; (3) a water extraction and alcohol precipitation method; (4) a method with combination of water extraction and macroporous resin purification; (5) a method with combination of alcohol extraction and macroporous resin purification;and (6) a classic decoction preparation method based on substances of classical famous prescriptions. The process for preparing the extract in the decoction can be optimized, so that the decoction can be prepared into various traditional Chinese medicine preparations; main components of the active component are defined. The invention provides powder of the decoction capable of invigorating spleenyang and tonifying stomach and various traditional Chinese medicine extract oral preparations; the prepared product is detected; the basis of the active substance of the traditional Chinese medicineextract of the decoction capable of invigorating spleen yang and tonifying stomach is clear and definite; the active substance is composed of a plurality of effective components according to a certainratio; and the content of the active substance is higher.

Description

technical field [0001] The invention relates to a preparation method and application of a traditional Chinese medicine extract of "Shengyang Yiwei Decoction", belonging to the technical field of traditional Chinese medicine. Background technique [0002] Chronic gastritis refers to various chronic gastric mucosal inflammatory lesions caused by different etiologies. It is a common disease, and its incidence rate ranks first among various gastric diseases. Its clinical feature is that the disease course is long, lingering and difficult to heal, which brings a lot of inconvenience to the life and work of the patient. Chronic gastritis is divided into chronic superficial gastritis, chronic erosive gastritis and chronic atrophic gastritis. Chronic superficial gastritis can develop into chronic atrophic gastritis. Chronic atrophic gastritis is often accompanied by intestinal glandular metaplasia and / or Dysplasia, and even develop into gastric cancer, endanger life and health. At...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/04A61P1/00A61P15/00
CPCA61K9/0095A61K36/076A61K36/232A61K36/233A61K36/237A61K36/238A61K36/258A61K36/284A61K36/481A61K36/484A61K36/65A61K36/71A61K36/718A61K36/725A61K36/752A61K36/884A61K36/8888A61K36/9068A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61P1/00A61P1/04A61P15/00A61K2300/00
Inventor 傅庆林严启新曾琪傅勃
Owner 湖北颐仁中医药研究总院有限公司
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