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Preparation method and application of traditional Chinese medicine extract for treating gynecological diseases such as irregular menstruation and dysmenorrhea

A technology of extracts and traditional Chinese medicines, which can be used in food ingredients, applications, diseases, etc. containing natural extracts, and can solve the problems of slow effect, disturbance of normal hormone secretion, and high probability of recurrence of irregular menstruation

Inactive Publication Date: 2018-11-16
海王百草堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, Western medicine mainly adopts clomiphene, diethylstilbestrol and other hormone drugs for treatment, which not only cannot cure the disease, but also increases the difficulty of treatment due to long-term use disrupting the secretion of normal hormones in the body, and there are certain disadvantages in use.
The recurrence rate of irregular menstruation is high, mainly because western medicine cannot improve the environment in the patient's body while treating the disease, which brings certain limitations to the treatment of irregular menstruation
[0005] At present, there are some outstanding problems in the traditional Chinese medicine for treating irregular menstruation: first, the effect is not obvious enough; ------The amount of menstruation is too small, or the amount of menstruation is too large, or the menstrual period is too long, or it is early, or it is late, and the timing of menstrual cramps is irregular, etc., which seriously affects the quality of life of women
[0008] Traditionally, the preparation process and taking method of this prescription are mainly water decoction: and the traditional water extraction process has no parameters, so it can be seen that the traditional process is rough, and it is inconvenient to take and carry, and the dosage is large, and it is not suitable for processing into Other dosage forms

Method used

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  • Preparation method and application of traditional Chinese medicine extract for treating gynecological diseases such as irregular menstruation and dysmenorrhea
  • Preparation method and application of traditional Chinese medicine extract for treating gynecological diseases such as irregular menstruation and dysmenorrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1 Water extraction method to prepare "Xuanyu Tongjing Decoction" Chinese medicine extract

[0047] Method 1: Take Radix Paeoniae Alba, Angelica, Cortex Paeonol, Gardenia, Radix Sinensis, Radix Bupleurum, Rhizoma Cyperi, Curcuma Chuan, Scutellaria baicalensis, and Glycyrrhizae as raw materials, and extract the raw materials with water as a solvent, and the weight ratio of each raw material is Paeoniae: Angelica: Paeonol: Gardenia: White Mustard: Bupleurum: Rhizoma Cyperi: Scutellaria baicalensis: Licorice = 5:5:5:3:2:1:1:1:1:1; Net selection of various medicinal materials, weighing 50 kg of white peony, 50 kg of angelica, 50 kg of paeonol, 30 kg of gardenia, 20 kg of white mustard seed, 10 kg of bupleurum, 10 kg of Cyperus cyperi, and 10 kg of Sichuan yujin , 10 kg of Scutellaria baicalensis, 10 kg of licorice, soaked in 2.5 tons of water for 20 minutes, heated and extracted 3 times (2 hours for the first time, 1 hour for the second time, 30 minutes for the third...

Embodiment 2

[0050] Example 2 Alcohol extraction method to prepare "Xuanyu Tongjing Decoction" Chinese medicine extract

[0051] Method 1: Take Radix Paeoniae Alba, Chinese Angelica, Cortex Paeonol, Gardenia jasminoides, White Mustard Seeds, Bupleurum, Cyperi Cyperi, Scutellaria baicalensis, Scutellaria baicalensis, and licorice as raw materials, and use 65% ethanol as a solvent to extract the raw materials. The weight ratio of each raw material is For white peony: angelica: paeonol: gardenia: white mustard seed: bupleurum: Cyperus: turmeric: scutellaria: licorice = 5:5:5:3:2:1:1:1:1:1:1; Cleanly select the above-mentioned medicinal materials, and weigh 50 kg of white peony, 50 kg of angelica, 50 kg of paeonol, 30 kg of gardenia, 20 kg of white mustard, 10 kg of bupleurum, 10 kg of Cyperus cyperi, 10 kg, 10 kg of Scutellaria baicalensis, 10 kg of licorice, soak in 2.5 tons of 65% ethanol for 20 minutes, extract by heating and reflux twice, each time for 1 hour (each time of reflux extracti...

Embodiment 3

[0054] Example 3 Preparation of "Xuanyu Tongjing Decoction" Chinese medicine extract by water extraction and alcohol precipitation method

[0055] Method 1: Take Radix Paeoniae Alba, Angelica, Cortex Paeonol, Gardenia, Radix Sinensis, Radix Bupleurum, Rhizoma Cyperi, Curcuma Chuan, Scutellaria baicalensis, and Glycyrrhizae as raw materials, and extract the raw materials with water as a solvent, and the weight ratio of each raw material is Paeoniae: Angelica: Paeonol: Gardenia: White Mustard: Bupleurum: Rhizoma Cyperi: Scutellaria baicalensis: Licorice = 5:5:5:3:2:1:1:1:1:1; Net selection of various medicinal materials, weighing 50 kg of white peony, 50 kg of angelica, 50 kg of paeonol, 30 kg of gardenia, 20 kg of white mustard seed, 10 kg of bupleurum, 10 kg of Cyperus cyperi, and 10 kg of Sichuan yujin , 10 kg of Scutellaria baicalensis, 10 kg of licorice, add 2.5 tons of water to soak for 20 minutes, heat and extract 3 times (2 hours for the first time, 1 hour for the second...

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Abstract

The invention provides a preparation method and application of soup for relieving depression and restoring menstrual flow (from FU Qingzhu's Obstetrics and Gynecology created by Fushan in the Qing Dynasty). The preparation method comprises: 1) water extraction, 2) alcohol extraction, 3) water extraction and alcohol precipitation, 4) water extraction combined with macroporous resin purification, 5)alcohol extraction combined with macroporous resin purification and 6) classic decoction preparation. The preparation method optimizes the process of extraction, prepares various preparations of traditional Chinese medicines, and defines the main components of the active part. The invention provides extract of FU Qingzhu's Obstetrics and Gynecology and various oral preparations of traditional Chinese medicine extract. The product is detected and the detection result shows that the active substances in the extract of FU Qingzhu's Obstetrics and Gynecology are clear and definite and comprise aplurality of active ingredients in a certain ratio and the content is high.

Description

technical field [0001] The invention relates to a preparation method and application of a traditional Chinese medicine extract of "Xuanyu Tongjing Decoction", belonging to the technical field of traditional Chinese medicine. Background technique [0002] Irregular menstruation refers to abnormal changes in menstrual cycle, menstrual period or menstrual flow, including menstrual cycle prolongation or shortening, menstrual cycle irregularity, menstrual flow too much or too little, menstrual period prolongation and dysmenorrhea, amenorrhea, premenstrual syndrome, etc. disease. Many bad habits and factors in life are the culprits that lead to menstrual disorders. [0003] Irregular menstruation can be mainly divided into four types: blood deficiency, often manifested as after menstruation, less quantity, pale color, clear quality, dizziness, palpitations, less sleep and more dreams, pale complexion, pale tongue with little coating Qi-deficiency type often manifests as early me...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A23L33/105A61P15/00
CPCA23L33/105A23V2002/00A61K36/232A61K36/233A61K36/31A61K36/484A61K36/539A61K36/65A61K36/71A61K36/744A61K36/8905A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61P15/00A61K2300/00A23V2200/30A23V2250/21
Inventor 严启新曾琪季宗念刘霞马安献
Owner 海王百草堂药业有限公司
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