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Preparation method and application of traditional Chinese medicine extract for treating yellowish leucorrhea, heat stranguria and other gynecological diseases

A technology of extracts and traditional Chinese medicines, applied in food ingredients, applications, diseases, etc. containing natural extracts, can solve the problems of taking, inconvenient to carry, unsuitable for processing, rough craftsmanship, etc., so as to facilitate market promotion and application, and facilitate The effect of processing preparations and methods is simple

Pending Publication Date: 2018-12-18
海王百草堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Traditionally, the preparation process and taking method of this prescription are mainly water decoction: and the traditional water extraction process has no parameters, so it can be seen that the traditional process is rough, and it is inconvenient to take and carry, and the dosage is large, and it is not suitable for processing into Other dosage forms

Method used

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  • Preparation method and application of traditional Chinese medicine extract for treating yellowish leucorrhea, heat stranguria and other gynecological diseases
  • Preparation method and application of traditional Chinese medicine extract for treating yellowish leucorrhea, heat stranguria and other gynecological diseases
  • Preparation method and application of traditional Chinese medicine extract for treating yellowish leucorrhea, heat stranguria and other gynecological diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1 Water extraction method to prepare "Yihuang Tang Fang" Chinese medicine extract

[0051] Method 1: Take yam, Gorgon fruit, Phellodendron cortex, Plantago seed, and Ginkgo fruit as raw materials, and use water as a solvent to extract the raw materials. The weight ratio of each raw material is: 1:10; cleanly select the above-mentioned medicinal materials, weigh 100 kg of yam, 100 kg of gorgon, 20 kg of cork, 10 kg of plantago, and 100 kg of ginkgo, soak in 3.3 tons of water for 20 minutes, heat and extract 3 times (the 2h once, 1h for the second time, 30min for the third time, each extraction time is calculated from after boiling), combine the extracts, concentrate the extracts obtained until the volume of the extracts is 3 times the weight of the raw materials, Obtain a preliminary concentrated extract; further dry to a relative density of 1.0g / cm 3 "Yihuang Decoction" traditional Chinese medicine extract (batch number 18010106).

[0052] Method 2: Take Chine...

Embodiment 2

[0054] Example 2 Alcohol extraction method to prepare "Yihuang Tang Fang" Chinese medicine extract

[0055] Method 1: Take Chinese yam, Gorgon fruit, Phellodendron cortex, Plantago seed, and Ginkgo fruit as raw materials, and extract the raw materials with 65% ethanol as a solvent. The weight ratio of each raw material is: 2: 1: 10; cleanly select the above medicinal materials, weigh 100 kg of yam, 100 kg of Gorgon, 20 kg of Phellodendron cork, 10 kg of plantain seed, 100 kg of ginkgo fruit, soak 3.3 tons of 65% ethanol for 20 minutes, heat and reflux Extract 2 times, 1h each time (each reflux extraction time is calculated from after boiling), the extracts are combined, left to stand for 24 hours, filtered to get the supernatant, and the supernatant is concentrated to 3 times of the original medicinal material to obtain a preliminary Concentrate the extract; further dry to a relative density of 1.0g / cm 3 "Yihuang Decoction" traditional Chinese medicine extract (batch number 1...

Embodiment 3

[0058] Example 3 Water Extraction and Alcohol Precipitation Method to Prepare "Yihuang Decoction" Chinese Medicine Extract

[0059] Method 1: Take yam, Gorgon fruit, Phellodendron cortex, Plantago seed, and Ginkgo fruit as raw materials, and use water as a solvent to extract the raw materials. The weight ratio of each raw material is: 1:10; cleanly select the above medicinal materials, weigh 100 kg of Chinese yam, 100 kg of gorgon, 20 kg of Phellodendron cork, 10 kg of plantain seed, and 100 kg of ginkgo, add 3.3 tons of water to soak for 20 minutes, heat and extract 3 times ( 2h for the first time, 1h for the second time, 30min for the third time, each extraction time is calculated from after boiling), combine the extracts, concentrate the extracts obtained until the volume of the extracts is 3 times the weight of the raw materials , to obtain a preliminary concentrated extract; slowly add an appropriate amount of ethanol while stirring, so that the alcohol content of the sol...

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Abstract

The invention provides a preparation method and an application of Yihuang Decoction Prescription (from Yihuang Decoction in Fu Qingzhu Gynecology by Fu Shan in the Qing Dynasty, referred to as YihuangDecoction Prescription in the description). The invention provides six preparation methods. The six preparation methods comprise: 1) a water extraction method; 2) an alcohol extraction method; 3) a water extraction and alcohol precipitation method; 4) a water extraction and macro-porous resin purification method; 5) an alcohol extraction and macro-porous resin purification method; and 6) a classic decoction preparation method (classical prescription standard substances). The prescription undergoes extract process optimization to prepare various traditional Chinese medicinal preparations, andthe main components of active parts are defined. The invention also provides a Yihuang Decoction Prescription extract, and various oral preparations of the traditional Chinese medicine extract. A result of detection of the prepared product shows that the active substance of the Yihuang Decoction Prescription traditional Chinese traditional medicine extract (composed of multiple effective components according to a certain ratio) are clear, and have high content.

Description

technical field [0001] The invention relates to a preparation method and application of a traditional Chinese medicine extract of "Yihuang Decoction", belonging to the technical field of traditional Chinese medicine. Background technique [0002] Damp-heat syndrome of hot stranguria and lower jiao belongs to the category of stranguria syndrome in traditional Chinese medicine, and there are records and discussions about this disease by physicians of all dynasties. "Golden Plaque Essentials Five Viscera Wind-cold Accumulation Disease" first thought that "the heat in the lower burner will drown in blood, and also make stranguria obstructed." And the cause of bladder heat", "Danxi Xinfa · Lin" also believes that "there are five types of stranguria, all belong to it", and "Jingyue Quanshu · Linzhuo" says: "The initial disease of stranguria is all due to the hot drama. , it’s impossible to tell.” Physicians of all dynasties believed that the main cause of Damp-Heat Syndrome due ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A23L33/105A61P15/00A61P13/00
CPCA23L33/105A23V2002/00A61K36/16A61K36/62A61K36/68A61K36/756A61K36/8945A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61P13/00A61P15/00A61K2300/00A23V2200/30A23V2250/21
Inventor 严启新曾琪季宗念刘霞马安献
Owner 海王百草堂药业有限公司
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