Traditional Chinese medicine extract for treating rheumatism and cardiovascular and cerebrovascular diseases as well as preparation method and application of traditional Chinese medicine extract

A technology of cardiovascular and cerebrovascular diseases and extracts, which is applied in the field of traditional Chinese medicine, can solve the problems such as the unclear basis of the active substances of the extracts, and achieve the effects of easy marketing and application, good reproducibility, and high desorption rate

Inactive Publication Date: 2018-09-28
湖北颐仁中医药研究总院有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Systematic optimization and confirmation of its main components to solve the problem of unclear active substances in extracts

Method used

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  • Traditional Chinese medicine extract for treating rheumatism and cardiovascular and cerebrovascular diseases as well as preparation method and application of traditional Chinese medicine extract
  • Traditional Chinese medicine extract for treating rheumatism and cardiovascular and cerebrovascular diseases as well as preparation method and application of traditional Chinese medicine extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1 A kind of preparation method (water extraction method) of traditional Chinese medicine extract for the treatment of rheumatism and cardiovascular and cerebrovascular diseases. Fried Cyperi Cyperi, Achyranthes Radix, Earthworm as raw materials, using water as a solvent to extract the raw materials, the weight ratio of each raw material is Gentiana chinensis, Rhizoma Chuanxiong, peach kernel, safflower, licorice, notopterygium, myrrh, angelica, Wulingzhi ( Fried with vinegar), Rhizoma Cyperi, Achyranthes bidentata, Dilong=1:2:3:3:2:1:2:3:2:1:3:2; cleanly select the above-mentioned medicinal materials, and weigh Gentiana in proportion 10 kg, Chuanxiong 20 kg, peach kernel 30 kg, safflower 30 kg, licorice 20 kg, notopterygium 10 kg, myrrh 20 kg, angelica 30 kg, Wulingzhi (stir-fried with vinegar) 20 kg, Cyperus cyperus 10 kg, achyranthes bidentata 30 kg, 20 kg earthworm, soaked in 2.5 tons of water for 20 minutes, heated and extracted 3 times (2 hours for the f...

Embodiment 2

[0040] Embodiment 2 A kind of Chinese medicine extract (alcohol extraction) for the treatment of rheumatism and cardiovascular and cerebrovascular diseases

[0041]Method 1: Take Gentiana chinensis, Chuanxiong, peach kernel, safflower, licorice, notopterygium, myrrh, angelica, Wulingzhi (stir-fried with vinegar), Cyperus cyperi, Achyranthes bidentata, and earthworm as raw materials, and extract the Raw materials, the weight ratio of each raw material is Gentiana chinensis, Chuanxiong, peach kernel, safflower, licorice, notopterygium, myrrh, angelica, Wulingzhi (stir-fried with vinegar), Cyperus cyperi, Achyranthes bidentata, earthworm=1:2:3:3: 2: 1: 2: 3: 2: 1: 3: 2; cleanly select the above-mentioned medicinal materials, and weigh 10 kg of Gentiana chinensis, 20 kg of Chuanxiong, 30 kg of peach kernels, 30 kg of safflower, 20 kg of licorice, and notopterygium 10 kg, 20 kg of myrrh, 30 kg of angelica, 20 kg of Wulingzhi (stir-fried with vinegar), 10 kg of Cyperus cyperi, 30 kg...

Embodiment 3

[0044] Embodiment 3 A kind of Chinese medicine extract for the treatment of rheumatism and cardiovascular and cerebrovascular diseases (water extraction and alcohol precipitation method)

[0045] Method 1: take Gentiana chinensis, Chuanxiong, peach kernel, safflower, licorice, notopterygium, myrrh, angelica, Wulingzhi (stir-fried with vinegar), Cyperus cyperi, Achyranthes bidentata, and earthworm as raw materials, and extract the raw materials with water as a solvent. The weight ratio of each raw material is Gentiana chinensis, Chuanxiong, peach kernel, safflower, licorice, notopterygium, myrrh, angelica, Wulingzhi (stir-fried with vinegar), Cyperus cyperi, Achyranthes bidentata, earthworm=1:2:3:3:2: 1: 2: 3: 2: 1: 3: 2; cleanly select the above-mentioned medicinal materials, and weigh 10 kg of Gentiana chinensis, 20 kg of Chuanxiong, 30 kg of peach kernels, 30 kg of safflower, 20 kg of licorice, and 10 kg of notopterygium , 20 kg of myrrh, 30 kg of angelica, 20 kg of Wulingzh...

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Abstract

The invention provides a traditional Chinese medicine extract for treating rheumatism and cardiovascular and cerebrovascular diseases as well as a preparation method and application of the traditionalChinese medicine extract. The traditional Chinese medicine extract is prepared from the following raw materials including radix gentianae macrophyllae, rhizoma chuanxiong, semen persicae, safflower,licorice root, rhizoma seu radix notopterygii, myrrh, Chinese angelica, trogopterus dung (stir fried with vinegar), rhizoma cyperi, radix achyranthis bidentatae and earthworm with the relative weightratio being 1 : 2 : 3 : 3 : 2 : 1 : 2 : 3 : 2 : 1 : 3 : 2. The preparation method comprises: 1) a water extraction method; 2) an ethanol extraction method; 3) a water extraction and alcohol precipitation method; 4) a method of combining water extraction with macroporous resin purification; 5) a method of combining ethanol extraction with macroporous resin purification; and 6) a classic decoction preparation method (a typical famous formula substance standard). Technological optimization is performed on the extract as for the formula, various traditional Chinese medicine preparations are prepared, and definition is performed on main components of active portions. By adopting the traditional Chinese medicine extract well as the preparation method and the application of the traditional Chinese medicine extract, a prepared product is detected, and the traditional Chinese medicine extract is clear and definite on the active substance basis and relatively high in content.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract of "Shentong Zhuyu Decoction", a preparation method and an application thereof, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Arthralgia in traditional Chinese medicine is caused by external evils such as wind, cold, dampness, and heat attacking the human body, blocking the meridians, and causing poor qi and blood. Pain and numbness occur in muscles, muscles, bones, and joints. Burning heat etc. are the main clinical manifestations of the disease. "On the Causes and Symptoms of Various Diseases Wind Arthralgia" says: "The arthralgia is caused by the combination of wind, cold and dampness, which together form arthralgia." [0003] Arthralgia is a concept of traditional Chinese medicine, which is equivalent to chronic autoimmune system diseases in modern medicine. Rheumatoid arthritis, rheumatoid arthritis, hyperosteogeny, spondylitis, ost...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P9/00A61P9/10A61P29/00A61K35/24A61K35/62
CPCA61K35/24A61K35/62A61K36/21A61K36/232A61K36/236A61K36/237A61K36/286A61K36/328A61K36/484A61K36/515A61K36/736A61K36/8905A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2236/55A61P9/00A61P9/10A61P29/00A61K2300/00
Inventor 傅庆林严启新曾琪傅勃
Owner 湖北颐仁中医药研究总院有限公司
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