Preparation methods and application of compound oyster extract for treating cough, primary hypertension and stroke

A technology of essential hypertension and extracts, which is applied in the field of traditional Chinese medicine, can solve the problems of inconvenient taking, carrying, unsuitable processing, and rough technology, and achieves a product that is convenient for market promotion and application, convenient for processing preparations, and simple methods Effect

Inactive Publication Date: 2019-01-11
三亚海王海洋生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0014] Traditionally, the preparation process and taking method of this prescription are mainly water decoction: and the traditional water extraction process has no parameters, so it can be seen that the traditional process is rough, and it is inconvenient to take and carry, and the dosage is large, and it is not suitable for processing into Other dosage forms

Method used

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  • Preparation methods and application of compound oyster extract for treating cough, primary hypertension and stroke
  • Preparation methods and application of compound oyster extract for treating cough, primary hypertension and stroke
  • Preparation methods and application of compound oyster extract for treating cough, primary hypertension and stroke

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1 Water extraction method to prepare "Sanjia Fumai Decoction" Chinese medicine extract

[0051] Method 1: Take licorice, rehmannia root, peony root, Ophiopogon japonicus, donkey-hide gelatin, hemp seed, oyster, turtle shell and tortoise shell as raw materials, and extract the raw materials with water as a solvent. The weight ratio of each raw material is licorice: rehmannia glutinosa: white peony root: Ophiopogon japonicus: Donkey-hide gelatin: Hemp seed: Oyster: Turtle shell: Tortoise shell = 6: 6: 6: 5: 3: 3: 5: 8: 10; cleanly select the above-mentioned medicinal materials, weigh 60 kg of licorice in proportion, 60 kg of rehmannia root, 60 kg of white peony root, 50 kg of Ophiopogon japonicus, 30 kg of donkey-hide gelatin, 30 kg of hemp seed, 50 kg of oyster, 80 kg of turtle shell, 100 kg of tortoise shell, soak in 5.2 tons of water for 20 minutes, heat and extract 3 times (the first 2h for the second time, 1h for the second time, 30min for the third time, eac...

Embodiment 2

[0054] Example 2 Alcohol extraction method to prepare "Sanjia Fumai Decoction" Chinese medicine extract

[0055] Method 1: Take licorice, rehmannia glutinosa, white peony root, Ophiopogon japonicus, donkey-hide gelatin, hemp seed, oyster, turtle shell and tortoise shell as raw materials, and extract the raw materials with 65% ethanol as a solvent. The weight ratio of each raw material is licorice: rehmannia: white Peony: Ophiopogon japonicus: Donkey-hide gelatin: Hemp seed: Oyster: Turtle shell: Tortoise shell = 6: 6: 6: 5: 3: 3: 5: 8: 10; cleanly select the above-mentioned medicinal materials, and weigh licorice 60% in proportion kg, 60 kg of rehmannia root, 60 kg of white peony root, 50 kg of Radix Ophiopogon japonicus, 30 kg of donkey-hide gelatin, 30 kg of hemp seed, 50 kg of oyster, 80 kg of turtle shell, 100 kg of tortoise shell, 5.2 tons of 65% ethanol for 20 minutes, heating and reflux extraction 2 times, 1 hour each time (each reflux extraction time is calculated from...

Embodiment 3

[0058] Example 3 Preparation of "Sanjia Fumai Decoction" Chinese medicine extract by water extraction and alcohol precipitation method

[0059] Method 1: Take licorice, rehmannia root, peony root, Ophiopogon japonicus, donkey-hide gelatin, hemp seed, oyster, turtle shell and tortoise shell as raw materials, and extract the raw materials with water as a solvent. The weight ratio of each raw material is licorice: rehmannia glutinosa: white peony root: Ophiopogon japonicus: Donkey-hide gelatin: Hemp seed: Oyster: Turtle shell: Tortoise shell = 6: 6: 6: 5: 3: 3: 5: 8: 10; cleanly select the above-mentioned medicinal materials, weigh 60 kg of licorice in proportion, 60 kg of rehmannia root, 60 kg of white peony root, 50 kg of Radix Ophiopogon japonicus, 30 kg of donkey-hide gelatin, 30 kg of hemp seed, 50 kg of oyster, 80 kg of turtle shell, 100 kg of tortoise shell, soak in 5.2 tons of water for 20 minutes, heat and extract 3 times ( 2h once, 1h for the second time, 30min for the ...

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Abstract

The invention provides preparation methods and application of a compound oyster extract for treating cough, primary hypertension and stroke. Six preparation methods provided by the invention are as follows: (1) a water extraction method, (2) an alcohol extraction method, (3) a water extraction and alcohol precipitation method, (4) a water extraction combined macroporous resin purification method,(5) alcohol extraction combined macroporous resin purification method, and (6) a classical soap agent preparation method (classic prescription substance standard). According to a prescription, the process of the extract is optimized and is prepared into various types of traditional Chinese medicine preparations, and main components of active parts are defined. The invention provides the compound oyster extract for treating cough, primary hypertension and stroke and various traditional Chinese medicine extract oral preparations. The prepared product is detected, the active substance basis of the extract for treating cough, primary hypertension and stroke is clear and definite (containing multiple effective components in a certain proportion), and the content is relatively high.

Description

technical field [0001] The invention relates to a preparation method and application of a traditional Chinese medicine extract of "Sanjia Fumai Decoction", belonging to the technical field of traditional Chinese medicine. Background technique [0002] The intuitive physiological manifestation of cough is that when the mucous membrane of the larynx or organs is irritated, the air is suddenly expelled from the lungs with a bursting noise when inhaling rapidly. Coughing is also a protective respiratory reflex action of the human body, through which the secretions in the respiratory tract or foreign objects entering the airway can be effectively removed. But coughing also has a negative side. It can spread tracheal lesions to adjacent small bronchi, aggravating the condition, and severe coughing can lead to respiratory bleeding. In addition, long-lasting and severe cough can affect rest, and is easy to consume physical strength, and can cause damage to the elastic tissue of the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P9/10A61P9/12A61P11/14A61K35/36A61K35/586A61K35/618
CPCA61K9/0095A61K35/36A61K35/586A61K35/618A61K36/484A61K36/60A61K36/65A61K36/71A61K36/804A61K36/8968A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P9/10A61P9/12A61P11/14A61K2300/00
Inventor 严启新曾琪刘霞王璐陈平原秦振龙
Owner 三亚海王海洋生物科技有限公司
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