Feed additive quinocetone and preparation method thereof

A technology of feed additive and quinocetone, which is applied in the field of feed additive quinocetone and its preparation, can solve the problems affecting the safety of feed additives, non-standard operation process, and affecting people's food safety, etc., to achieve the promotion of animal growth, wide antibacterial spectrum, and reaction Simple operation effect

Inactive Publication Date: 2012-03-14
许吉冲
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] At present, with the rapid development of social economy, the breeding industry is also developing rapidly. The feed and additives consumed by self-employed rural households to intensive large-scale farming are increasing exponentially. Especially for the formulation and production of feed additives, the market has never been The standardized operation process has led to a mixture of various additives. In order to pursue profits, a small number of individuals and manufacturers have ignored the safety of feed production and mixed in raw materials that cannot be added, making feed additives a problem product and greatly affecting feed additives. safety, which further affects the safety of common people's food

Method used

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Examples

Experimental program
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Effect test

Embodiment

[0010] (1) Synthesis of benzofurazan: Add 8.4g of o-nitroaniline and 0.06g of sodium dodecylsulfonate (SDS) into a 250mL single-necked bottle, then add 40mL of 20% NaOH solution, and drop while stirring at room temperature Add 92mL NaCIO solution with 0.9 available chlorine (0.953g available chlorine is equivalent to 1g sodium hypochlorite), continue to stir after dropping, the reaction solution becomes a light yellow suspension, TLC traces until the reaction is complete, suction filtration, and the filter cake is washed lightly 7.88g of yellow crystals, namely benzofurazan, the yield is 96.5%, the melting point is 72°C, no recrystallization is required, and the next reaction can be carried out directly;

[0011] (2) Synthesis of acetyl-3-methylquintaxel-1,4-dioxide (MAQO): 17.86 g of benzofurazan, 25 mL of triethylamine and 57 mL of ethanol were added to a 250 mL single-necked bottle. Stir at room temperature, add 16 mL of acetylacetone dropwise, continue stirring after dropp...

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Abstract

The invention relates to a feed additive, in particular to a feed additive quinocetone and a preparation method thereof and belongs to the technical field of chemical engineering. In the preparation method, o-nitroaniline is used as the starting raw material and the method comprises the following steps: oxidizing with sodium hypochlorite, and then reacting with acetylacetone and benzaldehyde to obtain quinocetone. Quinocetone can inhibit the synthesis of bacterial DNA to inhibit the growth of pathogenic microorganisms in the digestive tract, prevent or reduce diseases, protect good intestine bacteria and intestinal wall from the harms of microorganisms or parasites and promote the digestion and absorption of various nutrients. Therefore, the growth of animals can be promoted and the feed conversion rate can be increased.

Description

technical field [0001] The invention relates to a feed additive, in particular to a feed additive quinocetone and a preparation method thereof, belonging to the technical field of chemical industry. Background technique [0002] At present, with the rapid development of social economy, the breeding industry is also developing rapidly. The feed and additives consumed by self-employed rural households to intensive large-scale farming are increasing exponentially. Especially for the formulation and production of feed additives, the market has never been The standardized operation process has led to a mixture of various additives. In order to pursue profits, a small number of individuals and manufacturers have ignored the safety of feed production and mixed in raw materials that cannot be added, making feed additives a problem product and greatly affecting feed additives. The safety of food has further affected the safety of common people's food. Contents of the invention [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D241/52A23K1/16A61P31/04
Inventor 许吉冲
Owner 许吉冲
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