4 results about "O-nitroaniline" patented technology

The invention relates to an environment-friendly stripping agent of photosensitive ink for electroplating shielding, and belongs to the technical field of stripping agents. The preparation method comprises the following steps: carrying out nucleophilic addition on phosphorous acid and diethylene glycol monobutyl ether to obtain a modified precursor containing a phosphoester structure, carrying out Michael addition on the modified precursor and ortho-aminophenol to obtain a modified monomer, carrying out diazotization reaction on the modified monomer and ortho-nitroaniline, and then reducing to obtain the 2-(2-nitrophenyl)-1, 2, 4-thiadiazole. And finally, compounding the modified corrosion inhibitor with a stripping agent system, so as to obtain the environment-friendly stripping agent for the photosensitive ink for electroplating shielding. The environment-friendly stripping agent of the photosensitive ink for electroplating shielding has the advantages of environment friendliness, no toxicity, high stripping efficiency, broad-spectrum corrosion inhibition and few surface residues.

This invention belongs to the field of organic chemical synthesis technology, specifically relating to a method for synthesizing 2-fluoro-3-aminobenzoic acid, an important chemical intermediate. Specifically, o-nitroaniline is condensed with hydrated trichloroacetaldehyde and hydroxylamine hydrochloride to obtain 2-(hydroxyimino)-N-(2-nitrophenyl)acetamide; the resulting product undergoes an intramolecular Beckmann rearrangement to generate 7-nitroindigo; 7-nitroindigo undergoes Bayer-Villedge oxidation to generate 2-amino-3-nitrobenzoic acid; 2-amino-3-nitrobenzoic acid undergoes diazotization and halogenation reactions to generate 2-fluoro-3-nitrobenzoic acid or 2-chloro-3-nitrobenzoic acid; 2-fluoro-3-nitrobenzoic acid can be further reduced by nitro to obtain 2-fluoro-3-aminobenzoic acid; or, 2-chloro-3-nitrobenzoic acid can be esterified to obtain 2-chloro-3-nitrobenzoic acid ester, which can then be fluorinated, saponified, and reduced to obtain 2-fluoro-3-aminobenzoic acid. The raw materials of this invention are low in cost and readily available, and the entire reaction route has specific regioselectivity, making it suitable for industrial production.

The utility model discloses microwave vacuum drying equipment for ortho-nitroaniline, and belongs to the technical field of ortho-nitroaniline drying. The device comprises an outer machine shell, a feeding port is formed in one side of the outer machine shell, a sealing cover is movably hinged to one side of the feeding port, and a microwave generating device is fixedly arranged on the sealing cover; a crushing cylinder is rotationally arranged on the side, close to the feeding port, in the outer machine shell, the end, close to the feeding port, of the crushing cylinder is open, the other end of the crushing cylinder is blocked, screening holes are formed in the side wall of the crushing cylinder, the outer side of the crushing cylinder is slidably sleeved with a sealing cylinder, and the sealing cylinder is in sliding fit with the outer machine shell; a pushing mechanism used for pushing the sealing cylinder to move along the smashing cylinder is arranged on the outer machine shell. When the device is used, o-nitroaniline powder is heated through the microwave generating device, and the motor drives the crushing cylinder to rotate, so that the o-nitroaniline powder in the sealing cylinder can roll continuously, and the o-nitroaniline powder is uniformly heated.

The invention belongs to the technical field of organic synthesis, and discloses a preparation method of an intermediate 3, 4-diaminobromo-benzene, which comprises the following steps: S1, adding o-nitroaniline and a solvent, dropwise adding hydrobromic acid, dropwise adding hydrogen peroxide, carrying out heat preservation reaction, and treating after the reaction is completed to obtain a yellow solid; in the step S2, IM-1, a solvent, a catalyst and activated carbon are added, hydrazine hydrate is dropwise added, a stirring reaction is performed after dropwise adding, after the reaction is completed, activated carbon is filtered, the solvent is spin-dried, water is added for cooling, crystallization is performed, and a yellow solid is obtained through filtering. According to the method, o-nitroaniline is adopted as a starting raw material, and 3, 4-diaminobromo-benzene is prepared through hydrobromic acid substitution and hydrazine hydrate reduction. The invention discloses a drug molecule modular design, synthesis and optimization method based on molecular blocks, and aims to improve the research and development efficiency and molecular diversity of new drugs.