Paclitaxel compound preparation and preparation method thereof
A compound preparation, the technology of paclitaxel, which is applied in the field of medicine, can solve the problems of difficult absorption, low blood drug concentration, and difficulty in achieving anticancer curative effect, and achieve the effect of poor water solubility, good curative effect, and low oral bioavailability
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Embodiment 1-4
[0029] Embodiment 1-4, the preparation of paclitaxel compound preparation
[0030] The formulations of paclitaxel compound preparations in Examples 1-4 of the present invention are shown in Table 1.
[0031] The formula of table 1 embodiment 1-4 paclitaxel compound preparation (preparation by weight)
[0032] Numbering
Paclitaxel
20(s)-Ginsenoside Rg3
Example 1
1 part, 98% pure
0.1 parts, purity 97%
Example 2
1 part, 98% pure
0.25 parts, purity 97%
Example 3
1 part, 98% pure
0.5 parts, purity 97%
Example 4
1 part, 98% pure
0.25 parts, 70% purity
[0033] The unit of parts by weight is kilogram or gram, and the base value of 1 part can be designed according to the size of the required amount.
[0034] Conventional preparation methods can be used to prepare the paclitaxel compound preparation of the present invention. Paclitaxel and 20(s)-ginsenoside Rg3 can be used as compound medicinal active...
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