Iontophoretic transdermal drug delivery system

A transdermal drug delivery system and iontophoresis technology, applied in the field of new drug delivery systems, can solve the problems of low therapeutic efficiency of transdermal drug delivery, difficulty in transdermal drug delivery, etc. Compatibility and Penetration Enhancement

Active Publication Date: 2012-05-02
太原市怀诚医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the low efficiency of transdermal drug delivery and the difficulty of transdermal delivery of some macromolecules such as protein drugs are always the bottlenecks of this new drug delivery technology.

Method used

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  • Iontophoretic transdermal drug delivery system
  • Iontophoretic transdermal drug delivery system
  • Iontophoretic transdermal drug delivery system

Examples

Experimental program
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Embodiment Construction

[0021] Such as figure 1 As shown, the iontophoresis transdermal drug delivery system provided by the present invention includes a medium and low frequency pulse electron generator 1, a wire 2 and a hydrosol pulse electrode 3, and the middle and low frequency electron generator 1 is connected to the hydrosol pulse electrode 3 through a wire 2, The iontophoresis transdermal drug delivery system adjusts the transdermal drug delivery rate and the transdermal drug delivery amount by adjusting the wavelength, frequency, energy and width of the pulse current emitted by the middle and low frequency electron generator 1; There are buttons for adjusting the wavelength, frequency, energy and width of the pulse current on the device, and the wavelength, frequency, energy and width of the pulse current can be adjusted by operating the above buttons, thereby adjusting the transdermal drug delivery rate and transdermal drug delivery of the hydrosol pulse electrode 3 quantity.

[0022] Such ...

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PUM

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Abstract

The invention discloses an iontophoretic transdermal drug delivery system which comprises a low and middle frequency pulse electronic generator, a conductor wire and a hydrosol pulse electrode; the low and middle frequency pulse electronic generator is connected with the hydrosol pulse electrode through the conductor wire; a drug carrier of the hydrosol pulse electrode of the system is prepared from a medical hydrosol and has the characteristics of good compatibility and permeability promoting property to drugs and good compatibility with human bodies; and the drug carrier can be used as a transdermal drug delivery carrier for macromolecular drugs, micromolecular drugs, hydrophilic drugs, lipophilic drugs and the like and can also be used as a transdermal drug delivery carrier of some biological drugs of polypeptide, protein and the like. Low and middle frequency pulse electrons generated by the system have a good permeability promoting action and a directional introduction function to the drugs.

Description

technical field [0001] The invention relates to an iontophoresis transdermal drug delivery system, which belongs to the field of new drug delivery systems. Background technique [0002] Topical transdermal administration is a drug delivery method in which drugs are absorbed through the skin. After the drug is applied to the skin, it passes through the stratum corneum, diffuses through the skin, and activates the effect of treating diseases locally or systemically. Compared with traditional oral or injection administration, transdermal administration has many advantages, such as maintaining effective drug concentration through continuous transdermal action, avoiding peak and valley phenomena, reducing toxic and side effects, and avoiding drug degradation in the gastrointestinal tract And absorption, patients can self-administer medication or withdraw medication at any time. However, the low efficiency of transdermal drug delivery and the difficulty in transdermal delivery of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61N1/32
Inventor 赵前进赵利新赵杰王青刘斌
Owner 太原市怀诚医疗器械有限公司
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