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New application of Chinese caterpillar fungus

A technique for the use of Cordyceps sinensis, which is applied in the field of new uses of Cordyceps sinensis, and can solve the problems that the anti-inflammatory and cerebral ischemia effects of Cordyceps sinensis have not yet been reported.

Inactive Publication Date: 2012-07-18
刘振权
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although Cordyceps sinensis has such comprehensive health care functions that it is even called "fairy grass", so far, there is no report on the anti-inflammatory and cerebral ischemia effects of Cordyceps sinensis

Method used

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  • New application of Chinese caterpillar fungus
  • New application of Chinese caterpillar fungus
  • New application of Chinese caterpillar fungus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Crude Cordyceps sinensis mycelium (100 g) was extracted with 800 ml of distilled water and shaken for 72 hours at 37°C. The solution was centrifuged at 12000g for 30 minutes at 40°C. The supernatant was collected and lyophilized to form a powder. Pack into capsules and you're done.

Embodiment 2

[0069] Cordyceps sinensis mycelium is extracted with water to form freeze-dried powder, which is added to saturated hydroxypropyl β-cyclodextrin solution, stirred evenly, stirred for 1 hour, refrigerated overnight, suction filtered, and the filtrate is dried at low temperature to obtain cordyceps sinensis fungus powder and Inclusion complex powder of hydroxypropyl β-cyclodextrin.

Embodiment 3

[0071] Cordyceps sinensis mycelium is water-extracted to form freeze-dried powder, which is mixed with polyethylene glycol-6000 evenly, heated and melted, and then transferred to the dripping tank of the pill-dropping machine. , to prepare drop pills.

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Abstract

The invention provides a new application of Chinese caterpillar fungus. The Chinese caterpillar fungus has a new application in preparation of anti-inflammatory drugs, and further can be used for preparing drugs with neuroprotective effect to ischemic encephalopathy. The new application of Chinese caterpillar fungus is realized through lowering the levels of interleukin, tumour necrosis factor and intercellular adhesion molecules, and reducing the expression of nitric oxide synthase and cyclooxygenase by inhibiting the activity of transcription factor protein family NF-kB. The invention also provides a medicament composition which takes Chinese caterpillar fungus as the main component or one of the main components and is provided with therapeutic effect to ischemic encephalopathy.

Description

technical field [0001] The invention relates to the application field of Chinese herbal medicine, in particular to the new use of Cordyceps sinensis. Background technique [0002] Cerebrovascular diseases include hemorrhagic cerebral stroke and ischemic stroke, ischemic stroke, cerebral thrombosis, cerebral embolism, lacunar ischemic stroke and multiple ischemic stroke and small stroke all belong to ischemia Cerebral stroke is caused by cerebral vascular stenosis or occlusion, leading to cerebral blood flow blockage, resulting in ischemia, hypoxia, softening and even necrosis of cerebral tissue, resulting in cerebrovascular dysfunction and related symptoms. Ischemic stroke is the main type of cerebrovascular disease. About 85% of strokes are ischemic, and atherosclerosis is the basis. The biggest problem faced by patients who survive ischemic stroke is recurrence (5). The average recurrence rate during the year is as high as more than 40%) and the occurrence of other ischem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068A61P9/10A61P25/00A61P29/00
Inventor 刘振权
Owner 刘振权
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