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Traditional Chinese medicine preparation for treating diabetic syndrome and preparation method of same

A technology for traditional Chinese medicine preparations and syndromes, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, metabolic diseases, etc., and can solve problems such as liver and kidney function damage, lack of repair of pancreatic function, and ineffectiveness of pancreatic function repair.

Active Publication Date: 2013-08-07
吕宝俊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, insulin injection is inconvenient and painful, and it has no effect on the restoration of pancreatic function, while other hypoglycemic western medicines have greater damage to liver and kidney functions, and do not have the effect of repairing pancreatic function.

Method used

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  • Traditional Chinese medicine preparation for treating diabetic syndrome and preparation method of same
  • Traditional Chinese medicine preparation for treating diabetic syndrome and preparation method of same
  • Traditional Chinese medicine preparation for treating diabetic syndrome and preparation method of same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085](1) 310 parts of kudzu root, 310 parts of trichosanthin, 207 parts of schisandra, 207 parts of Ophiopogon japonicus, 207 parts of rehmannia glutinosa, 207 parts of poria cocos, 207 parts of black plum, 207 parts of astragalus, and 207 parts of licorice. First, add water with a pH value of 3.0, Add water at a weight ratio of 8 times the medicinal material. After ultrasonic treatment for 20 minutes, heat and extract for 2 hours, filter; then add water with a pH value of 5.5, add water at a weight ratio of 8 times the medicinal material, heat and extract for 1 hour, and filter Add water with a pH value of 7.5, add water to a weight ratio of 8 times the medicinal material, heat and extract for 1 hour, filter, combine the filtrate to concentrate under reduced pressure, add a certain concentration of ethanol, and stand for 24 hours, filter, The ethanol was recovered from the filtrate and concentrated under reduced pressure at 55°C to form a clear paste with a relative density o...

Embodiment 2

[0088] (1) 310 parts of kudzu root, 310 parts of trichosanthin, 207 parts of schisandra, 207 parts of Ophiopogon japonicus, 207 parts of rehmannia glutinosa, 207 parts of poria cocos, 207 parts of black plum, 207 parts of astragalus, and 207 parts of licorice. First, add water with a pH value of 4.0, Add 9 times the weight ratio of the amount of water to the medicinal material. After ultrasonic treatment for 25 minutes, heat and extract for 2 hours, and filter; then, add water with a pH value of 6. Add water with a pH value of 8, the amount of water added is 8 times the weight ratio of the medicinal material, heat and extract for 1 hour, filter, combine the filtrate to concentrate under reduced pressure, add a certain concentration of ethanol, and stand for 24 hours, filter, The ethanol was recovered from the filtrate and concentrated under reduced pressure at 55°C to form a clear paste with a relative density of 1.25 for later use;

[0089] (2) Take 207 parts of ginseng and p...

Embodiment 3

[0091] (1) 310 parts of kudzu root, 310 parts of trichosanthin, 207 parts of schisandra, 207 parts of Ophiopogon japonicus, 207 parts of rehmannia glutinosa, 207 parts of poria cocos, 207 parts of black plum, 207 parts of astragalus, and 207 parts of licorice. First, add water with a pH value of 5.0, Add 10 times the weight ratio of the amount of water to the medicinal material. After ultrasonic treatment for 30 minutes, extract by heating for 2 hours and filter; Add water with a pH value of 9, the amount of water added is 8 times the weight ratio of the medicinal material, heat and extract for 1 hour, filter, combine the filtrate to concentrate under reduced pressure, add a certain concentration of ethanol, and stand for 24 hours, filter, The ethanol was recovered from the filtrate and concentrated under reduced pressure at 55°C to form a clear paste with a relative density of 1.30 for later use;

[0092] (2) Take 207 parts of ginseng and pulverize it into fine powder, mix it...

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating diabetic syndrome and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following raw materials or prepared by taking water and / or ethanol extracts of the following raw materials as active ingredients and adding pharmaceutically acceptable additives: 310 parts of kudzuvine root, 310 parts of trichosanthes root, 207 parts of ginseng, 207 parts of schisandra, 207 parts of dwarf lilyturf turber, 207 parts of glutinous rehmannia, 207 parts of Indian buead, 207 parts of dark plum fruit, 207 parts of membranous milkvetch root and 207 parts of licorice. The preparation method comprises the following steps: firstly adding water withthe pH value of 3.0-5.0, wherein the amount of added water is 8-10 times the weight of medicinal materials; performing ultrasonic treatment for 20-30 min, then heating and extracting for 2 hours, andfiltering; then adding the water with the pH value of 5.5-7.0, wherein the amount of added water is 8-10 times the weight of the medicinal materials; heating and extracting for 1-1.5 hours, and filtering; further adding the water with the pH value of 7.5-9.0, wherein the amount of added water is 8-10 times the weight of the medicinal material; heating and extracting for 1-1.5 hours, filtering, merging filtrate, performing vacuum concentration, adding ethanol in a certain concentration, standing for 24 hours, filtering, recovering the ethanol from the filtrate, performing the vacuum concentration at the temperature of 55 DEG C to form a clear paste with the relative density of 1.20-1.30 for later use; and taking 207 parts of the ginseng, smashing into fine powder, mixing with the clear paste prepared in the step (1), adding excipients for preparing granules, uniformly mixing, pressing to form tablets, and coating thin-film coats for preparation.

Description

1. Technical field [0001] The invention relates to a traditional Chinese medicine preparation for clinically treating diabetic syndrome and a preparation method thereof, belonging to the field of traditional Chinese medicines. 2. Background technology [0002] Diabetes is a systemic progressive disease caused by disorders of glucose and lipid metabolism. It has many and serious complications. Its prevalence rate is gradually increasing in my country. The incidence of diabetes is increasing rapidly, and its incidence has become a trend of younger age, which has become a more and more serious public health problem in our country. [0003] At present, Western medicine is still the dominant treatment for diabetes, and insulin injection is ideal for severe diabetes patients. However, insulin injection is inconvenient and painful, and it has no effect on the restoration of pancreatic function, while other hypoglycemic western medicines have greater damage to liver and kidney funct...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K47/38A61K9/30A61K9/36A61P3/10
Inventor 吕宝俊吴松岭吴方忠
Owner 吕宝俊
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