Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Chickpea aqueous extract, and preparation and application thereof

A chickpea and water extract technology is applied to the chickpea water extract and its preparation and application fields, which can solve the problems of insulin deficiency, high physiological toxicity, discount of insulin action effect, etc., and achieves easy operation and simple process. Effect

Inactive Publication Date: 2012-08-22
XINJIANG MEDICAL UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The ability to produce insulin in patients with type 2 diabetes is not completely lost, and some patients even produce too much insulin, but the effect of insulin is greatly reduced, so the insulin in the patient's body may be in a state of relative deficiency
At present, there are related chemically synthesized DPPⅣ inhibitors, but they have high physiological toxicity and poor stability
[0004] It has been reported in the literature that plant chickpea has a certain degree of hypoglycemic effect, but the hypoglycemic mechanism is still unclear, and its impact on DPPⅣ has not been reported

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chickpea aqueous extract, and preparation and application thereof
  • Chickpea aqueous extract, and preparation and application thereof
  • Chickpea aqueous extract, and preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The chickpea aqueous extract proposed by the present invention is prepared through the following steps:

[0025] (1) Take chickpea seeds, add 10 times the weight of water, soak for 30 minutes, boil for 30 minutes, take out and keep the filtrate;

[0026] (2) Add 8 times the weight of water to the filter residue, soak for 30 minutes, boil for 30 minutes, and keep the filtrate;

[0027] (3) The two filtrates were combined, dried in a water bath to obtain a powder, and the aqueous extract of chickpea was obtained.

[0028] The chickpea aqueous extract prepared through the above steps has a yield of 20%, and is stored at -20°C for future use.

Embodiment 2

[0030] The chickpea aqueous extract proposed by the present invention is prepared through the following steps:

[0031] (1) Take chickpea seeds, add 10 times the weight of water, soak for 20 minutes, boil for 20 minutes, take out and keep the filtrate;

[0032] (2) Add 8 times the weight of water to the filter residue, soak for 20 minutes, boil for 20 minutes, and keep the filtrate;

[0033] (3) The two filtrates were combined, dried in a water bath to obtain a powder, and the aqueous extract of chickpea was obtained.

[0034] The chickpea aqueous extract prepared through the above steps has a yield of 10%. Store at -20°C for later use.

Embodiment 3

[0036] The chickpea aqueous extract proposed by the present invention is prepared through the following steps:

[0037] (1) Take chickpea seeds, add 10 times the weight of water, soak for 25 minutes, boil for 25 minutes, take out and keep the filtrate;

[0038] (2) Add 8 times the weight of water to the filter residue, soak for 25 minutes, boil for 25 minutes, and keep the filtrate;

[0039] (3) The two filtrates were combined, dried in a water bath to obtain a powder, and the aqueous extract of chickpea was obtained.

[0040] The chickpea aqueous extract prepared through the above steps has a yield of 16%. Store at -20°C for later use.

[0041] Application Example of Chickpea Water Extract in the Preparation of Dipeptidyl Peptidase IV Inhibitor

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a chickpea aqueous extract which is prepared by the following steps of: (1) taking chickpea seeds, adding 10 times the weight of water, soaking for 20-30 minutes, boiling for 20-30 minutes, taking out the chickpea seeds, and keeping a filtrate; (2) adding 8 times the weight of water to a residue, soaking for 20-30 minutes, boiling for 20-30 minutes, and keeping a filtrate; and (3) merging the two filtrates and drying with water bath into powder to obtain the chickpea aqueous extract. The chickpea aqueous extract provided by the invention has an obvious inhibition effect on dipeptidyl peptidase IV (DPPIV) activity and can be used for preparing a medicament for treating Type 2 diabetes.

Description

technical field [0001] The invention relates to a medicine, in particular to a chickpea aqueous extract and its preparation and application. Background technique [0002] Diabetes mellitus is a chronic comprehensive disease mainly caused by the disorder of glucose metabolism caused by absolute or relative insulin deficiency or decreased sensitivity of target cells to insulin. Among them, type 2 diabetes, also known as adult-onset diabetes, mostly occurs after the age of 35 to 40, accounting for more than 90% of diabetic patients. The ability to produce insulin in patients with type 2 diabetes is not completely lost. Some patients even produce too much insulin, but the effect of insulin is greatly reduced. Therefore, the insulin in the patient's body may be in a state of relative deficiency. Some oral drugs can be used to stimulate the secretion of insulin in the body, but some patients still need insulin therapy like type 1 diabetes in the later stage. In short, the short-...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P3/10A61K131/00
Inventor 李琳琳毛新民王烨杨珍珍陶义存骆新
Owner XINJIANG MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com