Medicine composition of damp itch lotion and preparation method of medicine composition

A composition and lotion technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of weak severe inflammation, solution precipitation, and large irritation of skin and mucous membranes. Rigorous, rational medication effect

Active Publication Date: 2012-09-26
HARBIN PHARM GROUP SANJING PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are quite a few traditional Chinese medicine lotions for treating gynecological diseases. However, these liquid preparations based on traditional Chinese medicine have a common disadvantage that the solution often precipitates out, which affects the stability and quality of the preparation, and the skin and mucous membranes are more irritating.
In addition, the study found that although the commercially available traditional Chinese medicine preparations for the treatment of gynecological diseases have certain curative effects to varying degrees, the target population is specific and non-specific mild vaginitis and other gynecological inflammation patients, and the effect on severe inflammation is relatively weak

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] [Example 1] The preparation of wet itching lotion: get Nepeta 350g, Peppermint 250g, Fangfeng 420g, Fructus Cnidii 420g, extract volatile oil to the utmost, the aqueous solution after distillation, filter, filtrate is concentrated to extractum, set aside; Sophora flavescens 900g, 450g Phellodendron cortex, 500g white fresh skin, 600g Kochia scoparia, 600g clove leaves. Filtrate once, combine the filtrates, concentrate to a clear paste with a relative density of 1.13-1.16 (measured at 80°C), combine with the above fluid extract, add ethanol to make the alcohol content reach 70%, let stand for 24 hours, filter, and recover the filtrate Ethanol until there is no alcohol smell, add water to about 9000ml, refrigerate at low temperature (0-7°C) for 24 hours, filter, add auxiliary materials polyethylene glycol-400 to the filtrate to make 100g, glycerin 400ml, essence 5ml and stir well; add ethanol 500ml to In the above solution, stir well, add water to adjust to 10000ml, and t...

Embodiment 2

[0022] [Example 2] Preparation of wet itching lotion: get Nepeta 500g, Peppermint 400g, Fangfeng 300g, Fructus Cnidii 300g, extract volatile oil to the utmost, distilled aqueous solution, filter, filtrate is concentrated to extractum, for subsequent use; Sophora flavescens 900g, 600g Phellodendron cortex, 400g white fresh skin, 600g Kochia scoparia, 700g clove leaves, five flavors, broken and decocted twice, the first time 10 times the amount of water for 2 hours, the second time 8 times the amount of water for 1 hour, divided Filtrate once, combine the filtrates, concentrate to a clear paste with a relative density of 1.13-1.16 (measured at 80°C), combine with the above fluid extract, add ethanol to make the alcohol content reach 70%, let stand for 24 hours, filter, and recover the filtrate Ethanol until there is no alcohol smell, add water to about 9000ml, refrigerate at low temperature (0-7°C) for 24 hours, filter, add auxiliary materials polyethylene glycol-400 to the filtr...

Embodiment 3

[0023] [Example 3] Preparation of Wet Itching Lotion: Get Nepeta 600g, Peppermint 400g, Fangfeng 400g, Fructus Cnidii 700g, extract volatile oil to the utmost, the aqueous solution after distillation, filter, filtrate is concentrated to extractum, set aside; Sophora flavescens 1000g, 600g Phellodendron cortex, 400g white fresh skin, 700g Kochia scoparia, 800g clove leaves. Filtrate once, combine the filtrates, concentrate to a clear paste with a relative density of 1.13-1.16 (measured at 80°C), combine with the above fluid extract, add ethanol to make the alcohol content reach 70%, let stand for 24 hours, filter, and recover the filtrate Ethanol until there is no alcohol smell, add water to about 9000ml, refrigerate at low temperature (0-7°C) for 24 hours, filter, add auxiliary materials polyethylene glycol-400 to the filtrate to 70g, glycerin 350ml, essence 5ml and stir well; add ethanol 500ml to In the above solution, stir well, add water to adjust to 10000ml, and then pack....

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Abstract

The invention provides a medicine composition of a damp itch lotion and a preparation method of the medicine composition. The medicine composition is mainly prepared from 3-15 parts of radix sophorae flavescentis, 2-10 parts of fineleaf schizonepeta herb, 2-10 parts of divaricate saposhnikovia root, 2-12 parts of phellodendron amurense, 2-10 parts of mentha haplocalyx, 2-10 parts of selinum japenious seed, 2-12 parts of shaggy-fruited dittany root bark, 3-15 parts of syringa lobata lindl leaves, 3-15 parts of broom cypress fruit, 0.2-1 part of polyethylene glycol-400, 2-10 parts of glycerol and 2-12 parts of alcohol. The medicine composition comprises nine Chinese medicinal herbs, has effects of clearing away heat and toxic materials, dispelling wind and eliminating dampness, and killing parasites to relieve itching, and is prepared into the lotion for preventing and treating diseases such as pruritus vulvae, trichomonad vaginitis, mycotic vaginitis, senile vaginitis and vulvareczema.

Description

technical field [0001] The invention relates to a medicinal composition of wet itching lotion, in particular to a medicinal composition of wet itching lotion using Chinese herbal medicine as a raw material medicine for treating gynecological genital diseases. The invention also relates to a preparation method of the medicinal composition of the wet itching lotion. Background technique [0002] With the deepening of my country's reform and opening up and socialist modernization, women's health care has been highly valued by the party and the government. Protecting women's physical and mental health is related to the implementation of prenatal and postnatal care, the improvement of the quality of the Chinese nation, and the great cause of the four modernizations of our country. At present, common gynecological diseases such as genital itching, trichomonas, fungal, senile vaginitis, genital eczema and other diseases seriously threaten people's health. Sexually transmitted dise...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P17/04
Inventor 刘占滨刘春凤孙宏宇范宁
Owner HARBIN PHARM GROUP SANJING PHARMACEUTICAL CO LTD
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