Cultivation house for test animal of genus Macaca without specific pathogen

Abstract

The invention relates to a cultivation house for test animal of genus Macaca without specific pathogen. Interior region of the cultivation house is composed of a working room, an observation room, a storehouse, a corridor, and several cultivation rooms; periphery of the cultivation room is sequentially installed with iron wire protective net, nanometer protective net and anti-rust angle iron keel from inside to outside, to completely enclose the cultivation room from exterior open part of the cultivation house; and device for supplementing preventative and health promoting / conditioning liquid is installed above the working room. Through the cultivation house structure, propagation of pathogens (bacteria, parasite and virus) carried by rodents, insects, birds and other animals can be effectively controlled; infection rate of cultivated SPF class test machin and rhesus due to exterior reasons (bacteria, parasite and virus) is reduced by 99%; and by adding the device for supplementing preventative and health promoting / conditioning liquid, uniform supply of microelements, vitamins and minerals can be satisfied to form favorable guarantee for test monkey health.

Description

technical field [0001] The invention relates to a breeding technology for experimental animals of the genus Rhesus, in particular to a breeding system and a building for experimental animals of the genus Rhesus without specific pathogens. Background technique [0002] In the field of experimental animal breeding technology, the experimental animals of the genus Rhesus mainly refer to two experimental monkeys, the experimental cynomolgus monkey and the experimental rhesus monkey. Because their genetic material has a homology of up to 98% with humans, their organizational structure, physiology Metabolism and other functions are very similar to humans, so it occupies an irreplaceable important position in life sciences, drug preclinical animal experiments, and other related disciplines, and is known as "the most sophisticated living experimental instrument". The experimental animals of the genus Rhesus macaques are divided into ordinary and specific pathogen-free experimental m...

AI Technical Summary

Problems solved by technology

[0003] (1) The existing macaque experimental animal houses cannot effectively isolate pathogen carriers (rodents, flies, mosquitoes and other insects, birds) from direct contact with reared animals, and cannot effectively control pathogens such as bacteria and parasites Spread;

[0004](2) There is no rehydration tank specially used for prevention and health care in the existing macaque experimental animal house

Therefore, at present, the elimination of pathogens is mainly carried out through regular house disinfection, sterilization, sanitation and cleaning of the environment, rodent extermination, etc., but the effect of using this method is not obvious, and there are the following problems: ① Long-term use of disinfectants affects Animal health; ②It is impossible to disperse birds and other animals all day long; ③The reproductive capacity of rodents is amazing and cannot be completely extinct; ④Mosquitoes breed at an alarming rate and cannot be completely eliminated

[0006] In addition, there are problems that cannot be prevented and cannot be adjusted

At present, most of the breeding houses of macaque experimental animals are equipped with automatic water supply devices, which is convenient for animals to drink water; under normal circumstances, it is necessary to carry out regular or irregular supplementary conditioning of nutrients, trace elements, and vitamins for experimental monkeys in breeding projects As well as the prevention and administration of epidemic diseases, etc., but the effect of mixing these drugs in the feed is not obvious, and because of the large amount of feed production, a lot of drugs are wasted; if the drug is given by intramuscular injection, animals need to be caught. It is more complicated, and the second is that it is too much nuisance to animals, which is not conducive to the normal growth of animals; therefore, it is simple and effective to use automatic water supply equipment for conditioning and disease prevention and rehydration.

Images