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Treatment method and solution for preventing blood from hanging on wall of human venous blood sample collection container

A technology for collecting containers and processing solutions, which is applied in chemical instruments and methods, laboratory containers, sensors, etc., can solve the problems of poor volatility of purified water, uneven silicification, and difficulty in drying, and achieves elimination of blood hanging on the wall and silicification. Good uniformity, easy drying effect

Active Publication Date: 2014-10-22
福州长庚医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, in the preparation of the siliconizing agent layer by the above preparation method, the solution prepared by using a water-soluble siliconizing agent and purified water will have the following insurmountable defects: it is not easy to dry; the siliconizing agent layer after drying and solidification will form a firm structure on the surface of the test tube , when used, the blood cells are not easy to fall off after adhesion, that is, the phenomenon of blood hanging on the wall; the uniformity of siliconization is poor;
[0012] After research, it was found that the above defects were caused by the use of purified water as a solvent for the preparation of the siliconizing agent layer: purified water has poor volatility, resulting in a higher drying temperature, so the siliconizing agent layer after high-temperature drying and curing will form a firm The structure is on the surface of the test tube; in addition, purified water has poor permeability as a solvent, which affects the uniformity of silicification; and the water-soluble silicification agent will produce foam after being dissolved in purified water, and uneven silicification will occur at the foam rupture

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1. Cleaning steps: clean the test tube;

[0022] 2. Steps for preparing the siliconizing agent layer: first prepare a solution according to the ratio of water-soluble siliconizing agent and absolute ethanol at a ratio of 1:1000 as a treatment solution for preventing blood from hanging on the wall, then completely soak the cleaned test tube in the solution for 3 minutes, and take it out test tube, and drain;

[0023] 3. Drying step: put the drained test tube in a drying oven, and dry it at a temperature of 100°C until it is completely dry;

[0024] 4. Step of adding additives: adding coagulant;

[0025] 5. Vacuuming step: then vacuumize the test tube;

[0026] 6. Sealing step: cover the safety head cover for sealing;

[0027] 7. Labeling steps: stick a paper label on the outer wall of the test tube,

[0028] 8. Packaging step: Arrange and fix the test tubes in the foam tray, and finally wrap them with plastic film.

[0029] Proof of effect:

[0030] 1. Take 5 dispo...

Embodiment 2

[0034] 1. Cleaning steps: clean the test tube;

[0035] 2. Steps for preparing the siliconizing agent layer: first prepare a solution according to the ratio of water-soluble siliconizing agent and absolute ethanol at a ratio of 1:500 as a treatment solution for preventing blood from hanging on the wall, then completely soak the cleaned test tube in the solution for 2 minutes, and take it out test tube, and drain;

[0036] 3. Drying step: place the drained test tube in a drying oven, and dry it at a temperature not higher than 80°C until it is completely dry;

[0037] Other steps are the same as in Embodiment 1.

[0038] Proof of effect:

[0039] 1. Take 5 disposable human venous blood sample collection containers prepared according to the above steps, and draw blood from blood donors to vacuum capacity;

[0040] 2. Turn the mouth of the test tube up, and when a large amount of serum is precipitated on the upper layer of the blood (usually 15-20 minutes), perform centrifugat...

Embodiment 3

[0043] 1. Cleaning steps: clean the test tube;

[0044] 2. Steps for preparing the siliconizing agent layer: first prepare a solution according to the ratio of water-soluble siliconizing agent and absolute ethanol at a ratio of 1:100 as a treatment solution for preventing blood from hanging on the wall, then completely soak the cleaned test tube in the solution for 1 minute, and take it out test tube, and drain;

[0045] 3. Drying step: place the drained test tube in a drying oven, and dry it at a temperature not higher than 50°C until it is completely dry;

[0046] Other steps are the same as in Embodiment 1.

[0047] Proof of effect:

[0048] 1. Take 5 disposable human venous blood sample collection containers prepared according to the above steps, and draw blood from blood donors to vacuum capacity;

[0049] 2. Turn the mouth of the test tube up, and when a large amount of serum is precipitated on the upper layer of the blood (usually 15-20 minutes), perform centrifugati...

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PUM

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Abstract

The invention provides a treatment method and a solution of a human body vein blood specimen collection container for preventing blood from being remained on a wall. The method comprises the following steps of: a cleaning step, a silicification agent layer preparation step, a drying step, an additive adding step, a vacuumizing step, a sealing step, a labeling step and a packaging step which are sequentially carried out, wherein the silicification agent layer preparation step is characterized by preparing the solution according to the proportion of water-soluble silicification agent to absolute ethyl alcohol being 1:(100-1000), then completely soaking a cleaned test tube into the solution for 1-3min, taking the test tube out, and draining. According to the method, the absolute ethyl alcohol is used as a dissolvent to prepare a silicification agent layer, has better volatility, is easy to dry, cannot enable the silicification agent layer to form a firm structure on the surface of the test tube, and has better permeability; and foam cannot be generated after the water-soluble silicification agent is dissolved in the absolute ethyl alcohol, so that the silicification uniformity is better, and the phenomenon that blood is remained on the wall after blood drawing through the test tube can be well eliminated.

Description

【Technical field】 [0001] The invention relates to a treatment method and a treatment solution for a human body venous blood sample collection container for preventing blood from hanging on the wall. 【Background technique】 [0002] In the preparation process of the disposable human venous blood sample collection container, the following steps are included: [0003] 1. Cleaning: clean the test tube; [0004] 2. Preparation of siliconizing agent layer: Soak the cleaned test tube in the solution prepared by water-soluble siliconizing agent and purified water for 1-3 minutes to prepare a coating on the inner wall of the test tube to prevent blood from hanging on the wall; [0005] 3. Drying: drying at 180°C for 2 hours; [0006] 4. Add additives: add coagulant; [0007] 5. Vacuuming: Then vacuum the test tube; [0008] 6. Sealing: Cover the safety head cover to seal; [0009] 7. Labeling: stick a paper label on the outer wall of the test tube, [0010] 8. Packaging: Arrange...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/154B01L3/00
Inventor 钟德优王利伟沈玉建
Owner 福州长庚医疗器械有限公司
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