48 results about "Venous blood sample" patented technology

Disclosed herein is a fully-integrated, disposable biochip for point-of-care testing of clinically relevant parameters. Specifically, in accordance with an embodiment of the present invention, the biochip is designed for POCT (point-of-care-testing) of an array of metabolic parameters including partial pressure of oxygen, Glucose, and Lactate concentration from venous blood samples. The biochip is fabricated on a low-cost plastic substrate using mass manufacturing compatible fabrication processes. Furthermore, the biochip contains a fully-integrated metallic micro-needle for blood sampling. The biochip also uses smart passive microfluidics in conjunction with low-power functional on-chip pressure generators for microfluidic sequencing. The design, configuration, assembly and operation of the biochip are ideally suited for a disposable biochip specifically targeted towards POCT applications.

The invention involves a device and method for ascertaining the functioning of the respiratory system and, in particular, determining the cardiac output of a patient. The device comprises an apparatus containing sensors for measuring the oxygen and carbon dioxide concentrations as well as the volume of air inhaled and exhaled by a patient. The patient is provided a mouthpiece for breathing into and out of the device, which subsequently measures oxygen partial pressures of the inhaled and exhaled air. In addition, the patient's arterial oxygen saturation is continuously measured through pulse oximetry and the pH and hemoglobin concentration is determined from a venous blood sample. From this data, the cardiac output of the patient may be calculated.

The present invention is directed to holders for a sensor. The holders apply pressure to the sensor to prevent a venous blood signal without dampening the arterial blood signal and are optically opaque to shield ambient light from reaching the sensor.

A methodology for converting venous blood values to arterial blood values provides the advantage of obviating the need for taking arterial blood samples. The method entails (i) measuring arterial oxygenation, (ii) measuring and estimating values of venous blood acid / base status and oxygenation status of a venous blood sample, and (iii) converting the venous blood values by applying a mathematical model for deriving blood acid / base status and oxygenation status into estimated arterial blood values.

The invention relates to a method for separating and purifying fetal nucleated erythrocytes, which is characterized by comprising the following steps: lysing the anucleated erythrocytes in the peripheral venous blood samples of pregnant women; adding a cell immobilization reagent to the lysed blood samples; and Cell separation is performed on a cell-fixed blood sample to obtain fetal nucleated red blood cells. The invention also relates to a kit for separating and purifying fetal nucleated red blood cells from peripheral venous blood samples of pregnant women. The invention greatly improves the yield and purity of isolated target cells, and lays a good foundation for subsequent various analyses.

The invention provides a disposable collection needle capable of synchronously collecting multiple tubes of venous blood samples, comprising a connecting seat, the bottom of the connecting seat is provided with a diversion hole communicating with the puncture needle, and the inside of the connecting seat is rotatably connected with a sealing plate, the sealing plate The outer side of the adjustment plate is connected with a swivel ring, the front of the adjustment plate is provided with tooth segments corresponding to the teeth, the inside of the fixed pipe is movably inserted with a positioning rod inserted into the inside of the adjustment plate, and the outer side of the positioning rod is fixedly connected with a floating plate. The suction component pumps air from the connecting seat and the puncture needle, and the floating plate drives the positioning rods to move up under the action of the suction force. After all the positioning rods leave the positioning grooves, the adjustment plate will move under the action of the spring and pass through the teeth. The segments and teeth drive the swivel to rotate, and the swivel drives the sealing plate to rotate through the connecting plate, so that the diversion hole is opened. By setting the positioning rod and the sealing plate, the suction force in each puncture needle is guaranteed to be consistent, thereby ensuring Consistent synchronization of blood sampling across multiple needles.