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Application of Chinese wolfberry root-bark aqueous extract to preparation of estrogen medicines

A technology of Cortex Dictica and water extract, which is applied in the field of application of Cortex Dictica water extract in the preparation of estrogen drugs, achieving the effects of simple preparation method, great clinical significance and low cost

Active Publication Date: 2012-12-05
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report about the estrogen-like activity of Digupi and its application in the preparation of estrogen drugs.

Method used

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  • Application of Chinese wolfberry root-bark aqueous extract to preparation of estrogen medicines
  • Application of Chinese wolfberry root-bark aqueous extract to preparation of estrogen medicines
  • Application of Chinese wolfberry root-bark aqueous extract to preparation of estrogen medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] In the specific implementation of the present invention, the water extract of Cortex Lycii is to decoct 100 g of Cortex Lycii with 1000 g of water 10 times its weight (i.e. 1000 mL), decocting twice for 2 hours each time, and combining the decoction twice , concentrating and drying under reduced pressure to obtain Digupi extract-like water extract, which was repeated three times in a row, with an average yield of 65.77%. Diseases, such as climacteric syndrome in women.

Embodiment 2

[0014] In the specific implementation of the present invention, the water extract of Cortex Lycii is to decoct 200 g of Cortex Lycii with 2000 g of water 10 times its weight (i.e. 2000 mL) twice, each time for 2 hours, and combine the decoction twice , concentrated and dried under reduced pressure to obtain Digupi extract-like water extract, which was repeated three times in a row, with an average yield of 65.67%. Diseases, such as menopausal syndrome medicine.

Embodiment 3

[0016] In the specific implementation of the present invention, the said Digupi water extract is to decoct Digupi (300g) with 3000g (ie 3000mL) of water 10 times its weight twice, each time for 2h, and combine the two water The decoction was concentrated and dried under reduced pressure to obtain the extract-like water extract of Digupi, which was repeated three times in a row, with an average yield of 65.58%. The water extract can be used to prepare estrogen drugs, which are used to treat diseases due to insufficient secretion of estrogen in the body. Caused diseases, such as climacteric syndrome in women.

[0017] According to the above-mentioned method, any amount of Cortex Lycii water extract can be produced by industrial production according to the ratio of Cortex Cortex Cortex and water, which can be used to prepare estrogen medicine, and effectively solve diseases caused by insufficient secretion of estrogen in the body (such as women's menopause. Syndrome, etc.), and h...

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Abstract

The invention relates to application of Chinese wolfberry root-bark aqueous extract to preparation of estrogen medicines. By the Chinese wolfberry root-bark aqueous extract, medicines for treating diseases caused by inappropriate secretion of estrogen in a human body can be effectively prepared. According to the technical scheme, Chinese wolfberry root-bark is decocted in water in an amount which is 10 times the weight of water twice, for two hours each time, water decoctions obtained twice are mixed, and the mixed water decoction is concentrated under reduced pressure and dried to form Chinese wolfberry root-bark extractum aqueous extract; the Chinese wolfberry root-bark aqueous extract can be effectively used for preparing medicines for treating relevant diseases caused by inappropriate secretion of estrogen in the human body, so that the application of the Chinese wolfberry root-bark aqueous extract to the preparation of the medicines for treating the relevant diseases caused by the inappropriate secretion of estrogen in the human body, such as the application of the Chinese wolfberry root-bark aqueous extract to preparation of a medicine for treating climacteric syndrome of women can be realized; a preparation method for the aqueous extract is simple, stable and reliable; through multiple times of experiments, the same and similar results are obtained; the method is convenient and low in cost; and the aqueous extract can be effectively used for preparing the estrogen medicines, the new medicinal application of the Chinese wolfberry root-bark is developed, and great clinical significance is brought.

Description

technical field [0001] The invention relates to a new application of medicine, in particular to the application of a water extract of Digupi in preparing estrogen drugs. Background technique [0002] Digupi is the dry root bark of Lycium chinense Mill. or Lycium barbarum L., a plant of the family Solanaceae. The roots are excavated in early spring or after autumn, washed, peeled off the root bark, and dried in the sun. Famous scholars of all dynasties have discussed and researched it, thinking that its nature is sweet and cold, and it returns to the lungs, kidneys, liver, and kidney channels, cools blood and removes steam, clears lungs and reduces fire. Indications for hot flashes due to yin deficiency, night sweats due to bone steaming, cough due to lung heat, hemoptysis, epistaxis, internal heat and thirst. After women enter menopause, the level of estrogen in the body drops, which in turn causes a series of symptoms, such as osteoporosis, cardiovascular and cerebrovascu...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P5/30A61P15/12
Inventor 郑晓珂冯卫生蒋贇刘朝妍王小兰
Owner HENAN UNIV OF CHINESE MEDICINE
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