Effective fractions of two plants in smilax for treatment of gouty arthritis, and extraction method

Abstract

The invention discloses an extract of the effective fractions of two Chinese herbal medicines (smilax macrophylla Ver. and smilax trinervula Miq.) in smilax for treatment of acute gouty arthritis, and extraction methods thereof. The extract of effective fractions are prepared by the following methods of: crushing the smilax macrophylla Ver. or the smilax trinervula Miq., extracting by decocting in water, collecting the water decoction, and filtering to obtain the extract; or crushing the smilax macrophylla Ver. or the smilax trinervula Miq., extracting by using 10-90% ethanol, collecting the ethanol extract, and recovery the ethanol to obtain the extract. The effective fractions not only can release the inflammation response of redness, swelling, heat, and aching of joints in acute phase, but also can reduce the uric acid level in blood aiming at the pathogenesis; and because the effective fractions has the effect of simultaneous treatment of principal and subordinate symptoms of gout, safe and reliable medicines with good curative effect for treatment of acute gouty arthritis can be prepared by using the effective fractions. The extraction technology for the effective fractions of the invention is simple, safe, easy to operate and low in cost, without the need of high temperature, high pressure or special equipment.

Description

technical field [0001] The invention relates to the effective parts of smilax plants for treating acute gouty arthritis, in particular to the effective parts of two Chinese herbal medicines, smilax smilax and three veins smilax, for treating acute gouty arthritis. The invention and the extraction method related to the effective part belong to the field of treating gouty arthritis with traditional Chinese medicine. Background technique [0002] Gouty arthritis is an acute inflammatory reaction caused by the deposition of sodium urate microcrystals in the tissues around the joints. Clinically, the main manifestations are repeated attacks of joint redness, swelling, heat and pain, and increased urine uric acid and blood uric acid. Over time, tophi is deposited in the articular cartilage, joint deformity, and even kidney stones. This disease belongs to the category of Arthralgia Syndrome in the traditional medicine of the motherland, commonly known as stubborn arthralgia, blo...

AI Technical Summary

Problems solved by technology

The existing gout medicines only have anti-inflammatory and analgesic effects on arthritis. If it can not only reduce uric acid, but also slow down the local inflammatory response, then it is the real significance of treating gouty arthritis.

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