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Method and component for controlling charged particles in liquid based on electrophoresis

A technology of charged particles and electrophoretic electrodes, applied in the field of microfluidic devices

Active Publication Date: 2013-01-16
吴传勇 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, this patent document (WO 2008 / 147568) mainly deals with the manipulation of liquid droplets, while the control of the particles contained in the liquid droplets is not mentioned, while the control of particles in the liquid, especially the control of charged particles, is of great importance to Sample preparation and biochemical analysis are very important

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  • Method and component for controlling charged particles in liquid based on electrophoresis
  • Method and component for controlling charged particles in liquid based on electrophoresis
  • Method and component for controlling charged particles in liquid based on electrophoresis

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Embodiment Construction

[0024] Embodiments of the present invention are described below through specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific implementation modes, and various modifications or changes can be made to the details in this specification based on different viewpoints and applications without departing from the spirit of the present invention.

[0025] see Figure 1 to Figure 3 . It should be noted that the diagrams provided in this embodiment are only schematically illustrating the basic idea of ​​the present invention, and only the components related to the present invention are shown in the diagrams rather than the number, shape and shape of the components in actual implementation. Dimensional drawing, the type, quantity and proportion of each component can be changed arb...

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Abstract

The invention provides a method and a component for controlling charged particles in liquid based on electrophoresis. The method provided by the invention comprises the steps of applying a voltage to two electrodes of a microflow component respectively to form a first voltage difference, changing the voltages on the two electrodes to form a second voltage difference after a first time duration, and continuing a second time duration so as to differently move the charged particles in liquid drop to be measured, thereby separating the particles conveniently, wherein at least one part of the charged particles in the liquid drop to be measured can be moved through the amplitude of at least one of the first voltage difference and the second voltage difference. According to the method and the component, with the adoption of effects such as electrowetting, electrophoresis and the like, the operation on the liquid drop can be realized, and meanwhile, the charged particles suspended in the liquid drop, especially the different particles with the same charge can be controlled.

Description

technical field [0001] The invention relates to the field of microfluidic devices, in particular to a method and device for manipulating charged particles in liquid based on electrophoresis. Background technique [0002] In recent years, microfluidic devices, also known as Lab-on-a-Chip and Micro Total Analysis Systems, have the advantages of less sample consumption, fast detection speed, low experimental cost, The advantages of easy automation, high detection repetition rate, and good data quality have attracted the attention of various industries. [0003] Traditional liquid manipulation requires a large amount of samples, many steps, and cumbersome, but digital microfluidic devices based on electrowetting-on-dielectric can not only control liquids with independent droplets as units operation, thus greatly increasing the ability of parallel processing and parallel detection of multiple samples; moreover, through the control of the electrodes contained in the device, it is...

Claims

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Application Information

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IPC IPC(8): G01N27/447B82Y15/00
CPCB01L3/00B01L2200/0668G01N27/44791B01D57/02B01L2400/0427B01L2400/0421B01L3/502792G01N27/447B03C5/00
Inventor 吴传勇
Owner 吴传勇
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