Preparation method of pharmaceutical composition for treating dysostosis multiplex

Abstract

The invention discloses a preparation method of a pharmaceutical composition for treating dysostosis multiplex, which aims to solve the problem of treatment of dysostosis multiplex. The invention is characterized by comprising the following active pharmaceutical ingredients in parts by weight: eria graminifolia Lindl., cotton tree bark, tuckahoe, dried orange peel, Lobed Actinostemma Herb, Trachelospermum jasminoides, kudzu root, Paris polyphylla, retinervus luffae fructus, murraya jasminorage, brown malt and charred rice sprout. The preparation method comprises the following steps: (1) extracting volatile oil from the kudzu root, cotton tree bark and Lobed Actinostemma Herb coarse powder for later use; (2) pulverizing the charred rice sprout into fine powder for later use; (3) extracting the Eria graminifolia Lindl., tuckahoe, dried orange peel, Trachelospermum jasminoides, retinervus luffae fructus, Paris polyphylla, murraya jasminorage and brown malt with water, precipitating with alcohol, and drying to obtain a primary material; and (4) spraying the volatile oil into the primary material, evenly mixing with the charred rice sprout fine powder, passing through a 60-mesh sieve, and encapsulating. The clinical experiment proves that the pharmaceutical composition for treating dysostosis multiplex has the characteristics of good curative effect and high safety, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of a medicinal composition for treating multiple abnormal osteogenesis. Background technique [0002] Dysostosis epiphysealis multiplex (DEM) is a genetic defect in the development of cartilage, characterized by abnormal bone formation in multiple bones, ossification growth disorder in patients, thick and short fingers, and it is more common in men than women. The age of onset is infants and adolescents. The hips, shoulders, and ankles are more common, followed by the knees, wrists, and elbows. The main clinical manifestations are pain in the hip and knee joints, limited mobility, difficulty in walking, and a swinging gait. Multiple dysostosis is characterized by epiphyseal stagnation and abnormal ossification: flattened, fragmented, symmetrical epiphyses, short stature, and early-onset osteoarthritis. Pathologically, the developing epiphyseal o...

AI Technical Summary

Problems solved by technology

Therefore, the treatment of this disease with "consolidating the root and nourishing the essence, nourishing the liver and kidney" is bound to fail to obtain good curative effect.