Anal fistula suppository and preparation method thereof

A technology of biological embolism and anal fistula, applied in medical science, prosthesis and other directions, can solve the problems of affecting the anti-infection ability of products, tissue regeneration ability, destroying three-dimensional structure, product instability, etc. High stability, guaranteed stability and uniformity
CN103272276AActive Publication Date: 2013-09-04BEIJING BIOSIS HEALING BIOLOGICAL TECH
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING BIOSIS HEALING BIOLOGICAL TECH
Publication Date
2013-09-04

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Abstract

The invention provides an anal fistula biological suppository and a preparation method thereof. The anal fistula biological suppository uses small intestine submucosa tissues of inbred line animals without cell and DNA (deoxyribonucleic acid) components as the raw material, completely reserves the extracellular matrix component and structure, and has a micropore structure. The preparation method of the anal fistula biological suppository comprises the following operation steps: determination of animal source, pretreatment and rough cleaning of small intestine tissues, virus inactivation, cell removal, DNA removal treatment, formation, packaging and sterilization. The anal fistula biological suppository prepared by the method uses an inbred line animal as an animal source, and thus, the hereditary features are pure, stable and uniform, thereby radically ensuring the stability and uniformity of different batches of products; and the anal fistula biological suppository has fewer animal source DNA residues, completely reserves the three-dimensional structure of natural ECM, and has the advantages of low immune source property and high infection resistance.
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Description

technical field

[0001] The invention relates to the technical field of animal-derived implantable medical devices, in particular to an anal fistula biological embolus and a preparation method thereof. Background technique

[0002] Anal fistula is a chronic infectious duct with the same perianal skin and rectum / anal canal. It is the inevitable result after the healing of perianal abscess. second. The main method of treatment of anal fistula is surgical treatment. Traditional surgical methods include anal fistula resection, thread therapy, drainage of fistula tract, transanorectal mucosal flap repair and other surgical methods. These surgical treatments all have problems of anal dysfunction and recurrence. Postoperative anal The incidence of incontinence is between 10% and 65%, the recurrence rate of postoperative anal fistula is between 10% and 20%, and the quality of life of patients is very poor. At present, it is believed that both the healing of anal fistula and the ...

Claims

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