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Application of medicine in treatment stent post-operation angiogenesis promoting medicines

A technology for promoting angiogenesis and drugs, applied in the application field, to achieve the effect of improving angiogenesis, low price, and abundant and easy-to-obtain raw materials

Inactive Publication Date: 2013-09-25
太仓市胜舟生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has been found clinically that some patients with coronary heart disease after coronary stenting still suffer from coronary artery stenosis and myocardial ischemia. and prognosis is also very important

Method used

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  • Application of medicine in treatment stent post-operation angiogenesis promoting medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Preparation of Traditional Chinese Medicine (1)

[0011] Take 10 parts of curcuma curcuma, 15 parts of Codonopsis pilosula, and 10 parts of Polygonatum odoratum in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

Embodiment 2

[0013] Preparation of Traditional Chinese Medicine (2)

[0014] Take 8 parts of curcuma curcuma, 13 parts of Codonopsis pilosula, and 8 parts of Polygonatum odoratum, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

Embodiment 3

[0016] Preparation of Traditional Chinese Medicine (3)

[0017] Take 12 parts of turmeric, 17 parts of Codonopsis pilosula, and 12 parts of Polygonatum odoratum, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

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Abstract

The invention relates to an application of a medicine in the preparation of coronary heart disease treatment stent post-operation myocardial ischemia disease medicines. The medicine is prepared by using 8-12 parts by weight of Radix Curcumae Aromaticae, 13-17 parts by weight of Radix Codonopsis and 8-12 parts by weight of Rhizoma Polygonati Odorati. The medicine is prepared through using pure traditional Chinese medicines, has a wide expectant range and has no toxic side effects. The medicine has the advantages of less raw material components, abundant and easily available raw materials, low price, simple preparation technology and suitableness for the popularized use. The above traditional Chinese medicine has the functions of coronary artery expansion, platelet aggregation resistance, thrombosis resistance, blood viscosity reduction, microcirculation improvement, and angiogenesis and endothelial restoration promotion, and has a short treatment course and a substantial effect when the medicine is used for treating myocardial ischemia.

Description

technical field [0001] The invention relates to an application, in particular to an application of a drug in promoting angiogenesis after stent surgery. Background technique [0002] Coronary atherosclerotic heart disease (coronary atherosclerotic heart disease) is referred to as coronary heart disease, which is myocardial damage caused by the imbalance between coronary blood supply and myocardial demand due to functional or organic lesions of the coronary arteries, also known as ischemia. Sexual heart disease (ischemic heart disease). [0003] For the treatment of coronary heart disease, the main principle is to improve the blood supply of coronary arteries and reduce myocardial ischemia and oxygen consumption, while treating and preventing the development of atherosclerosis. Among them, coronary heart disease stenting is one of the surgical treatment methods for coronary heart disease. Its basic principle is to insert a balloon catheter into a narrow blood vessel through ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10A61P7/02
Inventor 夏飞
Owner 太仓市胜舟生物技术有限公司
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