Composition for oral administration

A composition and oral technology, applied in the fields of application, food science, plant raw materials, etc., can solve the problem that it is difficult to achieve the content of iso-alpha acids, and achieve the effect of reducing bitterness or astringency

Inactive Publication Date: 2013-09-25
FUJIFILM CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, iso-alpha acids have a distinctive bitter taste that can be accompanied by a strong sense of discomfort when consumed or consumed in necessary amounts
Therefore, it is difficult to realize beverages and foods with high content of iso-alpha acids

Method used

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  • Composition for oral administration
  • Composition for oral administration

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0130] Dosing of Dispersion 1

[0131] 1 g of a 30% by mass iso-alpha acid stock solution (manufactured by Hopsteiner, Iso-Extract 30%) was diluted with 29 g of purified water to obtain a 1% by mass iso-alpha acid aqueous solution. Similarly, 1 g of ferric chloride hexahydrate (manufactured by Wako Pure Chemical Industries, Ltd., hereinafter abbreviated as ferric chloride) was diluted with 99 g of purified water to obtain a 1% by mass aqueous solution of ferric chloride.

[0132] Next, 6.42 g of purified water, 500 μL of a 1% by mass ferric chloride aqueous solution, gelatin (manufactured by Nitta Gelatin Co., Ltd., Collagen Peptide HBC-P20, molecular weight 15,000 to 40,000 ) 75.7 mg, stirred with a stirrer, and 1 mL of the above-mentioned 1 mass % aqueous solution of iso-alpha acid was added at one time to obtain 8 mL of an iron dispersion (iso-alpha acid concentration: 0.13 mass %) (dispersion 1).

Embodiment 2

[0134] Dosing of dispersion 2

[0135] Dispersion 2 was obtained in the same manner as in Example 1, except that the gelatin in Example 1 was changed to gum arabic (manufactured by Colloides Naturels International Co., Ltd., Instant gum AB, molecular weight: 200,000).

Embodiment 3

[0137] Dosing of Dispersion 3

[0138] Dispersion 3 was obtained in the same manner as in Example 1 except that the gelatin in Example 1 was changed to pullulan (manufactured by Hayashibara Biochemical Laboratory Co., Ltd., Japanese Pharmacopoeia pullulan, molecular weight: 70,000).

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Abstract

A composition for oral administration including: a water-insoluble material including a bitter or astringent substance such as an iso-alpha acid, and a polyvalent metal salt such as ferric chloride;and a dispersant such as gelatin, gum arabic, or other water-soluble polymer.

Description

technical field [0001] The present invention relates to compositions for oral use. Background technique [0002] In recent years, research on functional food raw materials focusing on the tertiary function of food has become active. Polyphenols, amino acids, and peptides are representative of such food raw materials. When these food raw materials are processed and used as foods or supplements, the taste, particularly bitterness or astringency of these food raw materials often becomes a problem. Low-molecular-weight physiologically active substances derived from plants generally have a bitter or astringent taste, and it is difficult to take them in a necessary amount even if they are food raw materials with health functions. [0003] Examples of such raw materials include iso-α acids such as isohumulone. Iso-alpha acid, which is an extract of hops, has been confirmed to have various effects such as anti-caries effect, anti-osteoporosis effect, growth inhibitory effect of H...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/22A23L27/00
CPCA61K36/185A23L29/219A23L29/25A23L29/262A23L29/274A23L29/284A23L29/288A23L27/84A23L27/86A23L33/105A23L33/16A61K2300/00
Inventor 辻畑茂朝桥本真一
Owner FUJIFILM CORP
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