Traditional Chinese medicine composition for treating hyperandrogenism of polycystic ovary syndrome

A technology for hyperandrogenemia and polycystic ovary, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of hindering the popularization and application of traditional Chinese medicine, difficult "target treatment of traditional Chinese medicine, lack of correspondence, etc., and reduce the Serum testosterone levels, ovulation promotion, hyperandrogen reduction and ovulation induction effects

Active Publication Date: 2014-01-01
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In addition, according to the traditional Chinese medicine theory, due to the lack of theoretical correspondence, the "test indicators" of modern medicine cannot be used as evaluation indicators for the efficacy of traditional Chinese medicine, so it is difficult for Chinese medicine to achieve accurate "target therapy". The popularization and application of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Raw materials: Anemarrhena 30g, Salt Phellodendron 30g, Rehmannia glutinosa 30g, Epimedium 30g, Cuscuta 30g.

[0081] Preparation method: decoct the above-mentioned crude drug with water for 2 times, add 8 times the amount of water each time, and decoct for 1.5 hours each time to obtain a decoction; filter the decoction, combine the two filtrates and concentrate to obtain the described Drugs for the treatment of hyperandrogenism in polycystic ovary syndrome.

Embodiment 2

[0083] Raw materials: Anemarrhena 36g, Salt Phellodendron 36g, Rehmannia glutinosa 30g, Epimedium 24g, Cuscuta 24g.

[0084] Preparation method: use 80% ethanol solution to reflux extract the above-mentioned Epimedium and Cuscuta 2 times, add 6 times the amount to extract for 1 hour each time, filter and combine respectively to obtain alcohol extract and medicinal residue, and set aside respectively; Extract the liquid to recover ethanol and concentrate until there is no alcohol smell to obtain a medicinal water liquid; mix Anemarrhena, Salt Phellodendron, and Rehmannia glutinosa with the above-mentioned medicinal residues and decoct twice with water, adding 8 times the amount of water each time and decocting for 1.5 hours, respectively Filtration and merging to obtain a decoction; the above-mentioned medicinal aqueous solution obtained after alcohol extraction and the decoction obtained by decocting are evenly mixed to obtain the traditional Chinese medicine composition for tr...

Embodiment 3

[0086] Raw materials: Anemarrhena 24g, Salt Phellodendron 24g, Rehmannia glutinosa 36g, Epimedium 30g, Cuscuta 36g.

[0087] Preparation method: extract above-mentioned epimedium and dodder with 8 times the amount of 70% ethanol solution under reflux for 1 hour, filter to obtain ethanol extract and dregs, respectively for later use; recover ethanol from the ethanol extract and concentrate until it has no alcohol smell, to obtain Aqueous solution containing medicine; mix Anemarrhena, Salt Phellodendron, Rehmannia glutinosa with the above-mentioned medicinal dregs, decoct 3 times with water, add 10 times the amount of water each time and decoct for 1 hour, filter and combine separately to obtain a decoction; extract the above-mentioned alcohol The obtained drug-containing aqueous liquid is uniformly mixed with the decoction obtained by decocting to obtain the traditional Chinese medicine composition for treating hyperandrogenism in polycystic ovary syndrome.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperandrogenism of polycystic ovary syndrome, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following bulk drugs in weight part: rhizoma anemarrhenae, salty amboynas of gtd, dried rehmannia root, herba epimedii, semen cuscutae and the like. The traditional Chinese medicine composition has a remarkable effect on treating the hyperandrogenism of polycystic ovary syndrome. The invention further discloses three preparation methods for the traditional Chinese medicine composition at the same time.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating polycystic ovary syndrome hyperandrogenism, and belongs to the field of traditional Chinese medicines. Background technique [0002] Polycystic ovary syndrome is a common reproductive endocrine disorder in women of childbearing age, accounting for 5%-10% of women of childbearing age. The main pathological changes of the disease include chronic anovulation, clinical or biochemical hyperandrogenism, and polycystic ovary. In gynecology, such patients often seek treatment for irregular menstruation, amenorrhea, and infertility. According to statistics, the disease accounts for about 30% of amenorrhea patients, and up to 90% of patients with ovulatory dysfunction infertility. [0003] The etiology, pathophysiology, and clinical manifestations of polycystic ovary syndrome have complex heterogeneity and obvious racial...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P15/08A61P5/28
Inventor 刘新敏
Owner GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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