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Synergistic diluent for root canal washing fluids and preparation method therefor

A diluent and root canal technology, applied in the medical field, can solve problems such as heavy odor, chemical burns, and patient discomfort

Inactive Publication Date: 2014-03-12
武汉伢典生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, because sodium hypochlorite solution has strong oxidizing properties, it is highly irritating, corrosive and allergic to the oral mucosal tissue. It can cause a burning sensation in the oral mucosal tissue in clinical use, and even produce chemical burns. Therefore, when it is used clinically , a dental rubber dam must be used
In addition, the sodium hypochlorite solution itself has a strong odor (bleach smell), which can cause severe discomfort to patients
(Research Progress of Sodium Hypochlorite as Root Canal Irrigation, Shi Yan, Yang Jian, "International Journal of Stomatology" 2008, 35 (4): 375-378) All these make the clinical application of sodium hypochlorite solution as a dental irrigating solution, highly regarded greatly restrict

Method used

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  • Synergistic diluent for root canal washing fluids and preparation method therefor
  • Synergistic diluent for root canal washing fluids and preparation method therefor
  • Synergistic diluent for root canal washing fluids and preparation method therefor

Examples

Experimental program
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Effect test

Embodiment 1

[0019] Dissolve 150 g of amino acid in 900 ml of distilled water, add 1 g of edible erythrosin to dissolve, and then adjust the pH to 8.6 with 10% (w / v) sodium hydroxide solution. Add 20g of sodium carboxymethylcellulose and stir to dissolve, add distilled water to 1000ml, mix well, and pack in colorless transparent plastic tubes, each filled with 10ml.

Embodiment 2

[0021] Dissolve 0.5 g of amino acid and 20 g of sodium chloride in 700 ml of distilled water, add 0.1 g of edible erythrosin to dissolve, and then adjust the pH value to 12.0 with 10% (w / v) sodium hydroxide solution. Add 20g of hydroxypropylmethylcellulose and stir to dissolve, add distilled water to 1000ml, mix well, and pack in colorless transparent plastic tubes, each filled with 10ml.

Embodiment 3

[0023] Dissolve 15g of amino acid and 5.6g of sodium chloride in 800ml of distilled water, add 0.05g of edible erythrosin to dissolve, adjust the pH value to 11.2 with 10% (w / v) sodium hydroxide solution, add distilled water to 1000ml, mix well Finally, it is packaged in a colorless transparent plastic tube, each filled with 5ml.

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Abstract

The invention relates to the medical technology field, and discloses a synergistic diluent for root canal washing fluids and a preparation method therefor. The synergistic diluents is packaged with a common enclosed container, and used for dilution, toxicity attenuation and synergy of root canal washing fluids in common use ( such as sodium hypochlorite solution, hydrogen peroxide solution and the like). The diluent mainly contains safe synergist amino acids, isoosmotic adjusting agents, gel thickening agents, alkaline pH conditioning agents, food colourings and / or essences and the like. The synergistic diluent can lower the damage of root canal washing fluids to oral mucosae obviously, the toxicity of the root canal washing fluids can be reduced, the peculiar smell of the root canal washing fluids can be eliminated, and the synergistic diluents is suitable for clinical application of dentistry.

Description

technical field [0001] The invention relates to the field of medical technology, and relates to a synergistic diluent for root canal irrigation and a preparation method thereof. Background technique [0002] Bacterial infection is the main pathogenesis of pulp disease and periapical disease, among which Gram anaerobic bacteria are the main pathogenic bacteria, and the detection rate is as high as 98.33%. (Evaluation of the clinical effects of four root canal irrigants, Zhou Yajun, "Journal of Baotou Medical College" 2007, 23(4): 386) Root canal treatment is the most common, effective and perfect treatment for pulp disease and periapical disease Treatment is an important means of preserving teeth. (Clinical analysis of EDTA root canal irrigation combined with micro-ultrasonic root canal technology on the root canal treatment of the elderly posterior teeth, Li Zhaohui, Bu Ling, Yu Bin, "Chinese Modern Doctor", 2010, 48(13): 29-30) in In the process of root canal treatment, t...

Claims

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Application Information

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IPC IPC(8): A61K33/00A61K31/198A61K31/401A61K31/405A61K31/4172A61P1/02
Inventor 岳力群黄安振吴敏
Owner 武汉伢典生物科技有限公司
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